Roughoid Dmel_CG1214 (Q29819759)

Protein found in Drosophila melanogaster

roughoid/rhomboid-3
CG1214 gene product from transcript CG1214-RA
ru
roughoid
rhomboid
rhomboid3
CG1214-PA
ru-PA
rhomboid 3
Rhomboid-3

Language	Label	Description	Also known as
English	Roughoid Dmel_CG1214	Protein found in Drosophila melanogaster	roughoid/rhomboid-3 CG1214 gene product from transcript CG1214-RA ru roughoid rhomboid rhomboid3 CG1214-PA ru-PA rhomboid 3 Rhomboid-3

Statements

1 reference

25 May 2022

Rhomboid-like superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W0F8

Peptidase S54, rhomboid, metazoan

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W0F8

Peptidase S54, rhomboid domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IEA

serine-type endopeptidase activity

5 references

9 May 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

9 May 2019

Rhomboid cleaves Star to regulate the levels of secreted Spitz

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

9 May 2019

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IBA

serine-type endopeptidase activity

4 references

8 April 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

8 April 2019

Rhomboid cleaves Star to regulate the levels of secreted Spitz

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

8 April 2019

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

cell component

endoplasmic reticulum

1 reference

9 May 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

integral component of plasma membrane

1 reference

9 May 2019

A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IEA

integral component of membrane

1 reference

9 May 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

integral component of Golgi membrane

1 reference

9 May 2019

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

late endosome membrane

1 reference

9 May 2019

Rhomboid cleaves Star to regulate the levels of secreted Spitz

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

biological process

compound eye morphogenesis

1 reference

9 May 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IMP

compound eye photoreceptor fate commitment

1 reference

9 May 2019

A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

1 reference

9 May 2019

Affecting Rhomboid-3 function causes a dilated heart in adult Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IMP

epithelial cell migration, open tracheal system

1 reference

9 May 2019

Rhomboid 3 orchestrates Slit-independent repulsion of tracheal branches at the CNS midline

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IMP

leg disc proximal/distal pattern formation

1 reference

9 May 2019

Developmental biology: signalling legacies.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W0F8&geneProductId=UniProtKB:Q9W0F8

determination method

IBA

compound eye cone cell fate commitment

1 reference

9 May 2019

A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IMP

adult chitin-containing cuticle pigmentation

1 reference

16 July 2018

Genetic Architecture of Abdominal Pigmentation in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W0F8&geneProductId=UniProtKB:Q9W0F8

determination method

IMP

positive regulation of protein secretion

1 reference

9 May 2019

Polarized secretion of Drosophila EGFR ligand from photoreceptor neurons is controlled by ER localization of the ligand-processing machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

1 reference

9 May 2019

A family of Rhomboid intramembrane proteases activates all Drosophila membrane-tethered EGF ligands

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W0F8

determination method

IDA

has part(s)

Peptidase S54, rhomboid domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9W0F8

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Roughoid Dmel_CG1214 (Q29819759)

Statements

Identifiers

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Roughoid Dmel_CG1214 (Q29819759)

Statements

Identifiers

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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