Matrix metalloproteinase 2 Dmel_CG1794 (Q29819298)

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Protein found in Drosophila melanogaster

CG1794 gene product from transcript CG1794-RB
matrix metalloprotease 2
matrix metalloproteinase-2
matrix metalloproteinase 2
matrix metalloproteinase
CG1794-PC
Mmp2-PD
matrix metalloprotinase 2
CG1794-PB
Mmp2-PC
Mmp2-PB
Mmp2
CG1794-PD

Language	Label	Description	Also known as
English	Matrix metalloproteinase 2 Dmel_CG1794	Protein found in Drosophila melanogaster	CG1794 gene product from transcript CG1794-RB matrix metalloprotease 2 matrix metalloproteinase-2 matrix metalloproteinase 2 matrix metalloproteinase CG1794-PC Mmp2-PD matrix metalloprotinase 2 CG1794-PB Mmp2-PC Mmp2-PB Mmp2 CG1794-PD

Statements

1 reference

25 May 2022

UniProt protein ID

Hemopexin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Metallopeptidase, catalytic domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

PGBD-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Peptidase M10A, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Hemopexin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase, metallopeptidase family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase M10, metallopeptidase family

1 reference

based on heuristic

inferred from protein domain or family

Peptidoglycan binding-like, protein family

1 reference

based on heuristic

inferred from protein domain or family

Hemopexin-like repeats, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

endopeptidase activity

determination method

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

peptidase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

zinc ion binding

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

hydrolase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

metalloendopeptidase activity

determination method

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

8 April 2019

Structural and enzymatic characterization of Drosophila Dm2-MMP, a membrane-bound matrix metalloproteinase with tissue-specific expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

external side of plasma membrane

determination method

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

integral component of membrane

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

determination method

1 reference

8 April 2019

Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

extracellular matrix

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

extracellular space

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

biological process

activation of innate immune response

determination method

1 reference

8 April 2019

Cleavage of PGRP-LC receptor in the Drosophila IMD pathway in response to live bacterial infection in S2 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

embryonic heart tube formation

determination method

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

cardioblast migration to the midline involved in heart rudiment formation

determination method

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

determination method

2 references

substrate-dependent cell migration

determination method

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

ventral cord development

determination method

1 reference

8 April 2019

Glia ECM interactions are required to shape the Drosophila nervous system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

open tracheal system development

determination method

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

tracheal outgrowth, open tracheal system

determination method

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

adult fat body development

determination method

1 reference

8 April 2019

Mmp1 and Mmp2 cooperatively induce Drosophila fat body cell dissociation with distinct roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

imaginal disc eversion

determination method

1 reference

8 April 2019

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

motor neuron axon guidance

determination method

1 reference

8 April 2019

Matrix metalloproteinases promote motor axon fasciculation in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

protein processing

determination method

1 reference

8 April 2019

Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

determination method

1 reference

8 April 2019

Matrix metalloproteinase 2 is required for ovulation and corpus luteum formation in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

basement membrane disassembly

determination method

1 reference

8 April 2019

Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

tracheal pit formation in open tracheal system

determination method

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

negative regulation of fibroblast growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

determination method

1 reference

8 April 2019

A secreted MMP is required for reepithelialization during wound healing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

cell-cell junction organization

determination method

1 reference

8 April 2019

Mmp1 and Mmp2 cooperatively induce Drosophila fat body cell dissociation with distinct roles

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

lateral inhibition

determination method

1 reference

8 April 2019

Spatial restriction of FGF signaling by a matrix metalloprotease controls branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

imaginal disc fusion, thorax closure

determination method

1 reference

8 April 2019

JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

basement membrane organization

determination method

1 reference

8 April 2019

Regulation of Drosophila matrix metalloprotease Mmp2 is essential for wing imaginal disc:trachea association and air sac tubulogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

negative regulation of canonical Wnt signaling pathway

determination method

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

fasciculation of motor neuron axon

determination method

1 reference

8 April 2019

Matrix metalloproteinases promote motor axon fasciculation in the Drosophila embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

negative regulation of extracellular matrix assembly

determination method

1 reference

8 April 2019

Matrix Metalloproteinases are required for membrane motility and lumenogenesis during Drosophila heart development.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

negative regulation of stem cell proliferation

determination method

1 reference

8 April 2019

A matrix metalloproteinase mediates long-distance attenuation of stem cell proliferation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

extracellular matrix organization

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

collagen catabolic process

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8MPP3

determination method

Peptidase M10A, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Peptidase, metallopeptidase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Hemopexin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Peptidase M10, metallopeptidase

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Hemopexin-like repeats

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Peptidoglycan binding-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8MPP3

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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