Head involution defective Dmel_CG5123 (Q29816984)

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Protein found in Drosophila melanogaster

hid-PB
head involuted
wrinkler
CG5123-PA
head involution defective 1
head-involution defective
CG5123 gene product from transcript CG5123-RA
head involution defective
hid-PA
CG5123-PB
head involution defect
head involuted defective
wrinkled
hid
head-involution-defective

Language	Label	Description	Also known as
English	Head involution defective Dmel_CG5123	Protein found in Drosophila melanogaster	hid-PB head involuted wrinkler CG5123-PA head involution defective 1 head-involution defective CG5123 gene product from transcript CG5123-RA head involution defective hid-PA CG5123-PB head involution defect head involuted defective wrinkled hid head-involution-defective

Statements

1 reference

25 May 2022

UniProt protein ID

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

protein binding

determination method

6 references

8 April 2019

The DIAP1 RING finger mediates ubiquitination of Dronc and is indispensable for regulating apoptosis.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Induction of apoptosis by Drosophila reaper, hid and grim through inhibition of IAP function

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Molecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitination

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

ubiquitin protein ligase binding

determination method

1 reference

8 April 2019

Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

BIR domain binding

determination method

1 reference

8 April 2019

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

determination method

1 reference

8 April 2019

The proapoptotic function of Drosophila Hid is conserved in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

biological process

instar larval or pupal development

determination method

1 reference

8 April 2019

Embryonic head involution and rotation of male terminalia require the Drosophila locus head involution defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

apoptotic process

determination method

4 references

8 April 2019

Apoptosis. The little devil of death.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Drosophila IAP antagonists form multimeric complexes to promote cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

open tracheal system development

determination method

1 reference

8 April 2019

Tracheal branch repopulation precedes induction of the Drosophila dorsal air sac primordium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

sex differentiation

determination method

1 reference

8 April 2019

Sex-specific apoptosis regulates sexual dimorphism in the Drosophila embryonic gonad.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

head involution

determination method

1 reference

8 April 2019

Embryonic head involution and rotation of male terminalia require the Drosophila locus head involution defective

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

intrinsic apoptotic signaling pathway in response to DNA damage

determination method

1 reference

8 April 2019

E2F and p53 induce apoptosis independently during Drosophila development but intersect in the context of DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

cellular response to starvation

determination method

1 reference

8 April 2019

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

response to red light

determination method

1 reference

8 April 2019

Novel features of cryptochrome-mediated photoreception in the brain circadian clock of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

programmed cell death

determination method

5 references

8 April 2019

Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Death to flies: Drosophila as a model system to study programmed cell death

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Genetic dissection of trophic interactions in the larval optic neuropil of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Cooperative functions of the reaper and head involution defective genes in the programmed cell death of Drosophila central nervous system midline cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of macroautophagy

determination method

1 reference

8 April 2019

Effector caspase Dcp-1 and IAP protein Bruce regulate starvation-induced autophagy during Drosophila melanogaster oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

salivary gland cell autophagic cell death

determination method

ecdysone-mediated induction of salivary gland cell autophagic cell death

determination method

1 reference

8 April 2019

A steroid-triggered transcriptional hierarchy controls salivary gland cell death during Drosophila metamorphosis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

larval midgut cell programmed cell death

determination method

1 reference

8 April 2019

A balance between the diap1 death inhibitor and reaper and hid death inducers controls steroid-triggered cell death in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of apoptotic process

determination method

3 references

8 April 2019

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

Regulation of apoptosis of rbf mutant cells during Drosophila development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

entrainment of circadian clock by photoperiod

determination method

1 reference

8 April 2019

Novel features of cryptochrome-mediated photoreception in the brain circadian clock of Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

8 April 2019

Systematic in vivo RNAi analysis of putative components of the Drosophila cell death machinery.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

regulation of organ growth

determination method

1 reference

8 April 2019

Drosophila myc regulates organ size by inducing cell competition.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

compound eye retinal cell programmed cell death

determination method

1 reference

8 April 2019

Cell proliferation, survival, and death in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

regulation of retinal cell programmed cell death

determination method

1 reference

8 April 2019

Patterning the fly eye: the role of apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

antennal morphogenesis

determination method

1 reference

8 April 2019

Role of programmed cell death in patterning the Drosophila antennal arista.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

dendrite morphogenesis

determination method

1 reference

8 April 2019

Local caspase activity directs engulfment of dendrites during pruning.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

cellular response to gamma radiation

determination method

1 reference

8 April 2019

Drosophila UTX coordinates with p53 to regulate ku80 expression in response to DNA damage.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

apoptotic signaling pathway

determination method

4 references

8 April 2019

Ras promotes cell survival in Drosophila by downregulating hid expression.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

The head involution defective gene of Drosophila melanogaster functions in programmed cell death.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

8 April 2019

The proapoptotic function of Drosophila Hid is conserved in mammalian cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of cellular response to X-ray

determination method

1 reference

8 April 2019

Drosophila melanogaster MNK/Chk2 and p53 regulate multiple DNA repair and apoptotic pathways following DNA damage

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of cysteine-type endopeptidase activity

determination method

1 reference

8 April 2019

The Drosophila caspase inhibitor DIAP1 is essential for cell survival and is negatively regulated by HID.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

determination method

1 reference

8 April 2019

Molecular mechanisms of DrICE inhibition by DIAP1 and removal of inhibition by Reaper, Hid and Grim.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

positive regulation of apoptotic process involved in development

determination method

1 reference

8 April 2019

Drosophila activated Cdc42 kinase has an anti-apoptotic function

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q24106

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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