death related ced-3/Nedd2-like caspase Dmel_CG7486 (Q29813244)

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Protein found in Drosophila melanogaster

death caspase-2
Ced-3-like/Nedd2-like protein
CG7486-PF
drosophila caspase
caspase
Dredd-PE
Dredd
CG7486-PD
CG7486-PG
CG7486-PE
death related ced-3/Nedd2-like protein
death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein
Dredd-PF
CG7486 gene product from transcript CG7486-RD
Dredd-PG
Dredd-PD
death related ced-3/Nedd2-like caspase

Language	Label	Description	Also known as
English	death related ced-3/Nedd2-like caspase Dmel_CG7486	Protein found in Drosophila melanogaster	death caspase-2 Ced-3-like/Nedd2-like protein CG7486-PF drosophila caspase caspase Dredd-PE Dredd CG7486-PD CG7486-PG CG7486-PE death related ced-3/Nedd2-like protein death-related ced-3/neural precursor cell expressed developmentally downregulated 2 (NEDD2)-like protein Dredd-PF CG7486 gene product from transcript CG7486-RD Dredd-PG Dredd-PD death related ced-3/Nedd2-like caspase

Statements

1 reference

25 May 2022

UniProt protein ID

caspase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IRY7

Peptidase C14, caspase non-catalytic subunit p10, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase C14, p20 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Peptidase C14A, caspase catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

endopeptidase activity

determination method

1 reference

1 January 2018

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

cysteine-type endopeptidase activity

determination method

7 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Patterning the fly eye: the role of apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

A comparison of programmed cell death between species

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

The fly caspases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Death to flies: Drosophila as a model system to study programmed cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

An emerging blueprint for apoptosis in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

protein binding

determination method

3 references

1 January 2018

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

dFADD, a novel death domain-containing adapter protein for the Drosophila caspase DREDD.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

peptidase activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

cysteine-type endopeptidase activator activity involved in apoptotic process

determination method

1 reference

1 January 2018

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

hydrolase activity

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

cysteine-type endopeptidase activity involved in execution phase of apoptosis

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

biological process

positive regulation of defense response to virus by host

determination method

1 reference

1 January 2018

A Novel System for the Launch of Alphavirus RNA Synthesis Reveals a Role for the Imd Pathway in Arthropod Antiviral Response

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

immune system process

determination method

1 reference

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

apoptotic process

determination method

7 references

1 January 2018

The evolution and genetics of innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Death to flies: Drosophila as a model system to study programmed cell death

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

The fly caspases

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Apoptosis-an introduction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

activation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

defense response

determination method

1 reference

1 January 2018

Interactions between the cellular and humoral immune responses in Drosophila.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria

determination method

sperm individualization

determination method

1 reference

1 January 2018

Multiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualization

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

protein processing

determination method

1 reference

1 January 2018

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

negative regulation of programmed cell death

determination method

1 reference

1 January 2018

Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

positive regulation of innate immune response

determination method

1 reference

1 January 2018

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

peripheral nervous system neuron development

determination method

1 reference

1 January 2018

NF-kappaB/Rel-mediated regulation of the neural fate in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

defense response to Gram-negative bacterium

determination method

7 references

1 January 2018

The immune response of Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Genetic analysis of Drosophila melanogaster susceptibility to intestinal Vibrio cholerae infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Ubiquitylation of the initiator caspase DREDD is required for innate immune signalling.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Genome-wide RNAi screen identifies genes involved in intestinal pathogenic bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

The Drosophila protein mustard tailors the innate immune response activated by the immune deficiency pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

peptidoglycan recognition protein signaling pathway

determination method

3 references

1 January 2018

A Spätzle-processing enzyme required for toll signaling activation in Drosophila innate immunity

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

The Drosophila caspase Dredd is required to resist gram-negative bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

1 January 2018

Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

execution phase of apoptosis

determination method

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8IRY7&geneProductId=UniProtKB:Q8IRY7

determination method

Peptidase C14, caspase non-catalytic subunit p10

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IRY7

Peptidase C14A, caspase catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IRY7

Peptidase C14, p20 domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q8IRY7

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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