Leukocyte-antigen-related-like Dmel_CG10443 (Q29813125)

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Protein found in Drosophila melanogaster

Lar-PF
CG10443-PB
Leukocyte-antigen-related-like
Lar-PH
CG10443-PI
Lar-PG
leukocyte- antigen-related-like
CG10443-PH
Lar-PD
Lar-PB
Lar-PA
Lar-PI
bypass
LAR receptor tyrosine phosphatase
CG10443-PA
CG10443-PD
CG10443-PF
Lar
CG10443-PG
CG10443 gene product from transcript CG10443-RI

Language	Label	Description	Also known as
English	Leukocyte-antigen-related-like Dmel_CG10443	Protein found in Drosophila melanogaster	Lar-PF CG10443-PB Leukocyte-antigen-related-like Lar-PH CG10443-PI Lar-PG leukocyte- antigen-related-like CG10443-PH Lar-PD Lar-PB Lar-PA Lar-PI bypass LAR receptor tyrosine phosphatase CG10443-PA CG10443-PD CG10443-PF Lar CG10443-PG CG10443 gene product from transcript CG10443-RI

Statements

1 reference

25 May 2022

UniProt protein ID

Fibronectin type III superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Protein-tyrosine phosphatase-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Immunoglobulin I-set, protein family

1 reference

based on heuristic

inferred from protein domain or family

Fibronectin type III, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine specific protein phosphatases domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

PTP type protein phosphatase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein-tyrosine phosphatase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

phosphoprotein phosphatase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

protein tyrosine phosphatase activity

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

8 April 2019

Modulation of catalytic activity in multi-domain protein tyrosine phosphatases

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

transmembrane receptor protein tyrosine phosphatase activity

determination method

1 reference

9 May 2019

A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

protein binding

determination method

3 references

9 May 2019

Liprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

The tyrosine kinase Abl and its substrate enabled collaborate with the receptor phosphatase Dlar to control motor axon guidance

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Drosophila liprin-alpha and the receptor phosphatase Dlar control synapse morphogenesis

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

heparin binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

hydrolase activity

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

phosphatase activity

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

protein tyrosine phosphatase activity

determination method

4 references

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Modulation of catalytic activity in multi-domain protein tyrosine phosphatases

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

The cytoplasmic adaptor protein Caskin mediates Lar signal transduction during Drosophila motor axon guidance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

basal plasma membrane

determination method

1 reference

9 May 2019

Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

integral component of membrane

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

Redundancy and compensation in axon guidance: genetic analysis of the Drosophila Ptp10D/Ptp4E receptor tyrosine phosphatase subfamily

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

cell leading edge

determination method

1 reference

9 May 2019

Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

biological process

protein dephosphorylation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

spermatogenesis

determination method

1 reference

9 May 2019

Identification of seven genes essential for male fertility through a genome-wide association study of non-obstructive azoospermia and RNA interference-mediated large-scale functional screening in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

5 references

9 May 2019

The Trio family of guanine-nucleotide-exchange factors: regulators of axon guidance.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Systematic identification of genes that regulate neuronal wiring in the Drosophila visual system

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Complex interactions amongst N-cadherin, DLAR, and Liprin-alpha regulate Drosophila photoreceptor axon targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

axon target recognition

determination method

1 reference

9 May 2019

Three Drosophila liprins interact to control synapse formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

motor neuron axon guidance

determination method

3 references

8 April 2019

The heparan sulfate proteoglycan syndecan is an in vivo ligand for the Drosophila LAR receptor tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

8 April 2019

The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

8 April 2019

Complex genetic interactions among four receptor tyrosine phosphatases regulate axon guidance in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

photoreceptor cell morphogenesis

determination method

1 reference

9 May 2019

Liprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

dephosphorylation

determination method

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

retinal ganglion cell axon guidance

determination method

1 reference

9 May 2019

Liprin-alpha is required for photoreceptor target selection in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

peptidyl-tyrosine dephosphorylation

determination method

1 reference

9 May 2019

A family of receptor-linked protein tyrosine phosphatases in humans and Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

R7 cell development

determination method

3 references

9 May 2019

Liprin-alpha has LAR-independent functions in R7 photoreceptor axon targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Local N-cadherin interactions mediate distinct steps in the targeting of lamina neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

Functions of the ectodomain and cytoplasmic tyrosine phosphatase domains of receptor protein tyrosine phosphatase Dlar in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

determination method

1 reference

9 May 2019

Complex interactions amongst N-cadherin, DLAR, and Liprin-alpha regulate Drosophila photoreceptor axon targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

regulation of axon extension involved in axon guidance

determination method

1 reference

9 May 2019

Complex interactions amongst N-cadherin, DLAR, and Liprin-alpha regulate Drosophila photoreceptor axon targeting

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

synaptic assembly at neuromuscular junction

determination method

1 reference

9 May 2019

The receptor protein tyrosine phosphatase LAR promotes R7 photoreceptor axon targeting by a phosphatase-independent signaling mechanism.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

positive regulation of filopodium assembly

determination method

1 reference

9 May 2019

Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

centripetally migrating follicle cell migration

determination method

1 reference

9 May 2019

Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

positive regulation of plasma membrane bounded cell projection assembly

determination method

1 reference

9 May 2019

Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

negative regulation of homophilic cell adhesion

determination method

1 reference

9 May 2019

Visual circuit assembly requires fine tuning of the novel Ig transmembrane protein Borderless.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

motor neuron axon guidance

determination method

4 references

9 May 2019

The heparan sulfate proteoglycan syndecan is an in vivo ligand for the Drosophila LAR receptor tyrosine phosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

The transmembrane tyrosine phosphatase DLAR controls motor axon guidance in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Complex genetic interactions among four receptor tyrosine phosphatases regulate axon guidance in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

9 May 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P16621

determination method

PTP type protein phosphatase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

immunoglobulin I-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

fibronectin type III

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

immunoglobulin subtype 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Protein-tyrosine phosphatase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Tyrosine specific protein phosphatases domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Protein-tyrosine phosphatase, catalytic

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

immunoglobulin subtype

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

immunoglobulin-like domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P16621

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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