Src oncogene at 64B Dmel_CG7524 (Q29812475)

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Protein found in Drosophila melanogaster

CG7524 gene product from transcript CG7524-RJ
Src proto oncogene sequence
Src64B-PK
CG7524-PJ
CG7524-PI
CG7524-PC
mRNA-like ncRNA in embryogenesis 5
Src64B-PB
Src64B
CG7524-PK
CG7524-PD
Src64B-PI
Src64B-PJ
CG7524-PE
Src64B-PC
CG7524-PB
CG7524-PH
Src64B-PE
Src64B-PH
Src oncogene at 64B
CG7524-PF
Src64B-PF
Src64B-PD

Language	Label	Description	Also known as
English	Src oncogene at 64B Dmel_CG7524	Protein found in Drosophila melanogaster	CG7524 gene product from transcript CG7524-RJ Src proto oncogene sequence Src64B-PK CG7524-PJ CG7524-PI CG7524-PC mRNA-like ncRNA in embryogenesis 5 Src64B-PB Src64B CG7524-PK CG7524-PD Src64B-PI Src64B-PJ CG7524-PE Src64B-PC CG7524-PB CG7524-PH Src64B-PE Src64B-PH Src oncogene at 64B CG7524-PF Src64B-PF Src64B-PD

Statements

1 reference

25 May 2022

UniProt protein ID

SH3-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

Protein kinase-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

SH2 domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

Serine-threonine/tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH2 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

SH3 domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase, catalytic domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Tyrosine-protein kinase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

protein kinase activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

non-membrane spanning protein tyrosine kinase activity

determination method

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

8 April 2019

Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

determination method

2 references

kinase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

transferase activity

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

determination method

1 reference

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

extrinsic component of cytoplasmic side of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

germline ring canal

determination method

1 reference

8 April 2019

Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

biological process

protein phosphorylation

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

transmembrane receptor protein tyrosine kinase signaling pathway

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

germarium-derived egg chamber formation

determination method

1 reference

8 April 2019

Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

ovarian nurse cell to oocyte transport

determination method

1 reference

8 April 2019

Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

cellularization

determination method

1 reference

8 April 2019

src64 and tec29 are required for microfilament contraction during Drosophila cellularization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

determination method

1 reference

8 April 2019

Src inhibits midline axon crossing independent of Frazzled/Deleted in Colorectal Carcinoma (DCC) receptor tyrosine phosphorylation.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

open tracheal system development

determination method

1 reference

8 April 2019

Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

salivary gland morphogenesis

determination method

1 reference

8 April 2019

Different Wnt signals act through the Frizzled and RYK receptors during Drosophila salivary gland migration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

long-term memory

determination method

1 reference

8 April 2019

The long-term memory trace formed in the Drosophila α/β mushroom body neurons is abolished in long-term memory mutants

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

regulation of actin polymerization or depolymerization

determination method

1 reference

8 April 2019

Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

female germline ring canal formation, actin assembly

determination method

1 reference

8 April 2019

Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

female germline ring canal stabilization

determination method

1 reference

8 April 2019

Src64 is required for ovarian ring canal morphogenesis during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

phosphorylation

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

mushroom body development

determination method

1 reference

8 April 2019

Gain‐of‐function screen identifies a role of the Src64 oncogene in Drosophila mushroom body development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

peptidyl-tyrosine phosphorylation

determination method

1 reference

8 April 2019

Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

actin cytoskeleton organization

determination method

1 reference

8 April 2019

Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

parallel actin filament bundle assembly

determination method

1 reference

8 April 2019

Drosophila Kelch regulates actin organization via Src64-dependent tyrosine phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

cell differentiation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

germarium-derived female germ-line cyst encapsulation

determination method

1 reference

8 April 2019

Csk differentially regulates Src64 during distinct morphological events in Drosophila germ cells.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

oocyte karyosome formation

determination method

1 reference

8 April 2019

Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

ovarian fusome organization

determination method

1 reference

8 April 2019

Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

adherens junction organization

determination method

1 reference

8 April 2019

Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

filtration diaphragm assembly

determination method

1 reference

8 April 2019

Src64B phosphorylates Dumbfounded and regulates slit diaphragm dynamics: Drosophila as a model to study nephropathies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

peptidyl-tyrosine autophosphorylation

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

positive regulation of epidermal growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

positive regulation of fibroblast growth factor receptor signaling pathway

determination method

1 reference

8 April 2019

A novel conserved phosphotyrosine motif in the Drosophila fibroblast growth factor signaling adaptor Dof with a redundant role in signal transmission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

positive regulation of sevenless signaling pathway

determination method

1 reference

8 April 2019

Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

negative regulation of synaptic assembly at neuromuscular junction

determination method

1 reference

8 April 2019

Fak56 functions downstream of integrin alphaPS3betanu and suppresses MAPK activation in neuromuscular junction growth

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

regulation of synaptic plasticity

determination method

1 reference

8 April 2019

C-terminal Src Kinase Gates Homeostatic Synaptic Plasticity and Regulates Fasciclin II Expression at the Drosophila Neuromuscular Junction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

determination method

1 reference

8 April 2019

Src64 is involved in fusome development and karyosome formation during Drosophila oogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

epithelial cell-cell adhesion

determination method

1 reference

8 April 2019

Dual function of Src in the maintenance of adherens junctions during tracheal epithelial morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

positive regulation of torso signaling pathway

determination method

1 reference

8 April 2019

Raf activation is regulated by tyrosine 510 phosphorylation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P00528

determination method

tyrosine-protein kinase, active site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

serine-threonine/tyrosine-protein kinase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

tyrosine-protein kinase, catalytic domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

protein kinase domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

protein kinase, ATP binding site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P00528

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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