Nicastrin Dmel_CG7012 (Q29812214)

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Protein found in Drosophila melanogaster

CG7012-PC
CG7012-PD
dNicastrin
nicastrin
agoraphobic
Nct-PA
CG7012-PE
CG7012-PA
Nct-PE
CG7012 gene product from transcript CG7012-RC
Nct-PC
Nct
Nct-PD

Language	Label	Description	Also known as
English	Nicastrin Dmel_CG7012	Protein found in Drosophila melanogaster	CG7012-PC CG7012-PD dNicastrin nicastrin agoraphobic Nct-PA CG7012-PE CG7012-PA Nct-PE CG7012 gene product from transcript CG7012-RC Nct-PC Nct Nct-PD

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9VC27

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

endopeptidase activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

determination method

1 reference

8 April 2019

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

plasma membrane

determination method

1 reference

1 January 2018

Mapping organelle proteins and protein complexes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

recycling endosome

determination method

1 reference

8 April 2019

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

gamma-secretase complex

determination method

1 reference

8 April 2019

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

plasma membrane

determination method

1 reference

8 April 2019

Mapping organelle proteins and protein complexes in Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

biological process

membrane protein ectodomain proteolysis

determination method

1 reference

14 January 2019

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

cytoskeleton organization

determination method

1 reference

14 January 2019

Drosophila nicastrin is essential for the intramembranous cleavage of notch

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

Notch signaling pathway

determination method

4 references

14 January 2019

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

14 January 2019

Drosophila nicastrin is essential for the intramembranous cleavage of notch

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

14 January 2019

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

14 January 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

photoreceptor cell morphogenesis

determination method

1 reference

14 January 2019

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

regulation of compound eye photoreceptor development

determination method

1 reference

8 April 2019

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

R8 cell development

determination method

1 reference

14 January 2019

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VC27&geneProductId=UniProtKB:Q9VC27

determination method

Notch receptor processing

determination method

5 references

8 April 2019

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Drosophila nicastrin is essential for the intramembranous cleavage of notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

Notch signaling pathway

determination method

8 references

8 April 2019

Epsin-Dependent Ligand Endocytosis Activates Notch by Force.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Nicastrin is required for Presenilin-mediated transmembrane cleavage in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Nicastrin controls aspects of photoreceptor neuron specification and differentiation in the Drosophila eye.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Drosophila nicastrin is essential for the intramembranous cleavage of notch

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

Nicastrin is required for gamma-secretase cleavage of the Drosophila Notch receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

Notch receptor processing, ligand-dependent

determination method

1 reference

8 April 2019

In vivo reconstitution of gamma-secretase in Drosophila results in substrate specificity.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VC27

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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