Transient receptor potential Dmel_CG7875 (Q29811942)

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Protein found in Drosophila melanogaster

CG7875-PB
trp
transient photreceptor potential
trp-PB
transient receptor potential
trp-PA
Cosens-Manning mutant
transient receptor potential protein
CG7875-PA
INAD localization-B
CG7875 gene product from transcript CG7875-RA

Language	Label	Description	Also known as
English	Transient receptor potential Dmel_CG7875	Protein found in Drosophila melanogaster	CG7875-PB trp transient photreceptor potential trp-PB transient receptor potential trp-PA Cosens-Manning mutant transient receptor potential protein CG7875-PA INAD localization-B CG7875 gene product from transcript CG7875-RA

Statements

1 reference

25 May 2022

UniProt protein ID

transient receptor potential channel, canonical

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19334

Ankyrin repeat-containing domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P19334

transient receptor potential channel

1 reference

Transporter Classification Database ID

2 October 2019

based on heuristic

hierarchical database ID heuristic

Ion transport domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat-containing domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Ankyrin repeat, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

ion channel activity

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

calcium channel activity

determination method

7 references

8 April 2019

The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

protein binding

determination method

6 references

8 April 2019

Regulation of the TRP Ca2+ channel by INAD in Drosophila photoreceptors

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

TRPgamma, a drosophila TRP-related subunit, forms a regulated cation channel with TRPL.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

An Exquisitely Specific PDZ/Target Recognition Revealed by the Structure of INAD PDZ3 in Complex with TRP Channel Tail

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

The INAD scaffold is a dynamic, redox-regulated modulator of signaling in the Drosophila eye

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Drosophila TRP channels require a protein with a distinctive motif encoded by the inaF locus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

calmodulin binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

light-activated ion channel activity

determination method

1 reference

8 April 2019

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

identical protein binding

determination method

1 reference

8 April 2019

Drosophila TRP and TRPL are assembled as homomultimeric channels in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

protein homodimerization activity

determination method

1 reference

8 April 2019

Coassembly of TRP and TRPL produces a distinct store-operated conductance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

protein heterodimerization activity

determination method

1 reference

8 April 2019

Coassembly of TRP and TRPL produces a distinct store-operated conductance

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

store-operated calcium channel activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

inositol 1,4,5 trisphosphate binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

integral component of plasma membrane

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

determination method

2 references

inaD signaling complex

determination method

determination method

4 references

8 April 2019

Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Novel mechanism of massive photoreceptor degeneration caused by mutations in the trp gene of Drosophila.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Dissecting independent channel and scaffolding roles of the Drosophila transient receptor potential channel

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Light-regulated subcellular translocation of Drosophila TRPL channels induces long-term adaptation and modifies the light-induced current.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

cation channel complex

determination method

1 reference

16 July 2018

Coassembly of TRP and TRPL produces a distinct store-operated conductance

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19334&geneProductId=UniProtKB:P19334

determination method

rhabdomere microvillus membrane

determination method

1 reference

8 April 2019

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

biological process

retina homeostasis

determination method

1 reference

8 April 2019

PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

calcium ion transport

determination method

3 references

8 April 2019

The TRP family of cation channels: probing and advancing the concepts on receptor-activated calcium entry.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

The trp gene is essential for a light-activated Ca2+ channel in Drosophila photoreceptors.

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

manganese ion transport

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

mitochondrion organization

determination method

1 reference

8 April 2019

PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

visual perception

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

phototransduction

determination method

1 reference

8 April 2019

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

phototransduction, visible light

determination method

1 reference

8 April 2019

The Drosophila light-activated conductance is composed of the two channels TRP and TRPL.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

sensory perception of sound

determination method

1 reference

8 April 2019

Drosophila auditory organ genes and genetic hearing defects

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

sensory perception of smell

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

protein localization

determination method

1 reference

8 April 2019

TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

olfactory learning

determination method

1 reference

8 April 2019

TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

light-induced release of internally sequestered calcium ion

determination method

1 reference

8 April 2019

TRP and calcium stores in Drosophila phototransduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

response to stimulus

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

detection of light stimulus involved in visual perception

determination method

1 reference

8 April 2019

Proper function of the Drosophila trp gene product during pupal development is important for normal visual transduction in the adult

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

detection of light stimulus involved in sensory perception

determination method

1 reference

8 April 2019

Scaffolding protein INAD regulates deactivation of vision by promoting phosphorylation of transient receptor potential by eye protein kinase C in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

regulation of cytosolic calcium ion concentration

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

transmembrane transport

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

calcium ion transmembrane transport

determination method

4 references

16 July 2018

Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19334&geneProductId=UniProtKB:P19334

determination method

16 July 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19334&geneProductId=UniProtKB:P19334

determination method

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19334&geneProductId=UniProtKB:P19334

determination method

16 July 2018

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P19334&geneProductId=UniProtKB:P19334

determination method

cellular response to anoxia

determination method

1 reference

8 April 2019

Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

inorganic cation transmembrane transport

determination method

1 reference

8 April 2019

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

calcium ion transmembrane transport

determination method

5 references

8 April 2019

Metabolic stress reversibly activates the Drosophila light-sensitive channels TRP and TRPL in vivo.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P19334

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Transporter Classification Database ID

2 references

Transporter Classification database

13 March 2020

Transporter Classification database

29 April 2020

Sitelinks

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Wikisource(0 entries)

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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