Discs large 1 Dmel_CG1725 (Q29810201)

L27 domain superfamily

1 reference

PDZ superfamily

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Disks large 1-like

1 reference

L27 domain, protein family

1 reference

Guanylate kinase-like domain, protein family

1 reference

PDZ domain, protein family

1 reference

L27-1, protein family

1 reference

SH3 domain, protein family

1 reference

Guanylate kinase/L-type calcium channel beta subunit, protein family

1 reference

Guanylate kinase, conserved site, protein family

1 reference

epidermal growth factor receptor binding

found in taxon

Drosophila melanogaster

1 reference

25 May 2022

1 reference

25 May 2022

1 reference

8 April 2019

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

protein binding

3 references

8 April 2019

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Intrinsic disorder in the C-terminal domain of the Shaker voltage-activated K+ channel modulates its interaction with scaffold proteins

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

ionotropic glutamate receptor binding

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

plasma membrane

Discs-Large and Strabismus are functionally linked to plasma membrane formation

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

8 April 2019

A genome-wide resource for the analysis of protein localisation in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

HDA

8 April 2019

Subcellular localisations of the CPTI collection of YFP-tagged proteins in Drosophila embryos.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

HDA

septate junction

Role of the Crumbs complex in the regulation of junction formation in Drosophila and mammalian epithelial cells

8 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

8 April 2019

Genetic studies define MAGUK proteins as regulators of epithelial cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Epithelial Cell Polarity and Cell Junctions inDrosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

8 April 2019

Gliotactin and Discs large form a protein complex at the tricellular junction of polarized epithelial cells in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

smooth septate junction

1 reference

8 April 2019

A novel protein complex, Mesh-Ssk, is required for septate junction formation in the Drosophila midgut.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

ionotropic glutamate receptor complex

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

apicolateral plasma membrane

1 reference

8 April 2019

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

presynaptic membrane

1 reference

8 April 2019

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

neuron projection

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

terminal bouton

1 reference

8 April 2019

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

perinuclear region of cytoplasm

1 reference

8 April 2019

Temporal and spatial expression of Drosophila DLGS97 during neural development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

type I terminal bouton

1 reference

8 April 2019

Fragile X mental retardation protein regulates trans-synaptic signaling inDrosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

type Ib terminal bouton

1 reference

8 April 2019

The translational repressor Pumilio regulates presynaptic morphology and controls postsynaptic accumulation of translation factor eIF-4E.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

tricellular tight junction

1 reference

8 April 2019

Gliotactin and Discs large form a protein complex at the tricellular junction of polarized epithelial cells in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

subsynaptic reticulum

1 reference

8 April 2019

Neurexin, Neuroligin and Wishful Thinking coordinate synaptic cytoarchitecture and growth at neuromuscular junctions.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

postsynaptic density membrane

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

negative regulation of transcription by RNA polymerase II

biological process

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

establishment of mitotic spindle orientation

1 reference

8 April 2019

Canoe binds RanGTP to promote PinsTPR/Mud-mediated spindle orientation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

cell fate specification

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

morphogenesis of a polarized epithelium

1 reference

8 April 2019

Apicobasal polarization: epithelial form and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

morphogenesis of an epithelium

1 reference

14 January 2019

Epithelial Cell Polarity and Cell Junctions inDrosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31007&geneProductId=UniProtKB:P31007

cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

signal transduction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

chemical synaptic transmission

Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Quantal size and variation determined by vesicle size in normal and mutant Drosophila glutamatergic synapses.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

multicellular organism development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

pole plasm protein localization

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

dorsal closure

1 reference

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

mating behavior

1 reference

8 April 2019

DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

male courtship behavior

1 reference

8 April 2019

DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

protein localization

1 reference

8 April 2019

Recruitment of scribble to the synaptic scaffolding complex requires GUK-holder, a novel DLG binding protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

regulation of Notch signaling pathway

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

morphogenesis of follicular epithelium

1 reference

8 April 2019

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

establishment or maintenance of polarity of follicular epithelium

1 reference

8 April 2019

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

morphogenesis of larval imaginal disc epithelium

1 reference

8 April 2019

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

8 April 2019

ovarian follicle cell development

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

regulation of border follicle cell delamination

1 reference

8 April 2019

Integration of epithelial patterning and morphogenesis in Drosophila ovarian follicle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

anterior/posterior axis specification, follicular epithelium

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

regulation of epidermal growth factor receptor signaling pathway

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

regulation of cell population proliferation

1 reference

8 April 2019

Genetic studies define MAGUK proteins as regulators of epithelial cell polarity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

gravitaxis

1 reference

8 April 2019

Gravitaxis in Drosophila melanogaster: a forward genetic screen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

receptor clustering

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

establishment or maintenance of neuroblast polarity

1 reference

14 January 2019

Epithelial Cell Polarity and Cell Junctions inDrosophila

http://www.ebi.ac.uk/QuickGO/annotations?protein=P31007&geneProductId=UniProtKB:P31007

locomotor rhythm

1 reference

8 April 2019

DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

negative regulation of imaginal disc growth

1 reference

8 April 2019

Yorkie and JNK Control Tumorigenesis in Drosophila Cells with Cytokinesis Failure.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

positive regulation of synaptic assembly at neuromuscular junction

1 reference

8 April 2019

Syndapin promotes formation of a postsynaptic membrane system in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

GMP metabolic process

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

regulation of receptor signaling pathway via JAK-STAT

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

GDP metabolic process

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

positive phototaxis

1 reference

8 April 2019

DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

behavioral response to ethanol

1 reference

8 April 2019

DlgS97/SAP97, a neuronal isoform of discs large, regulates ethanol tolerance

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

synaptic assembly at neuromuscular junction

1 reference

8 April 2019

PAR-1 kinase phosphorylates Dlg and regulates its postsynaptic targeting at the Drosophila neuromuscular junction.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

establishment of spindle orientation

1 reference

8 April 2019

Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

cell fate commitment involved in pattern specification

1 reference

8 April 2019

Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

receptor localization to synapse

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

cell-cell adhesion

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31007

1 reference

SH3 domain

1 reference

PDZ domain

1 reference

Guanylate kinase-like domain

1 reference

Guanylate kinase/L-type calcium channel beta subunit

1 reference

L27 domain

1 reference

Guanylate kinase, conserved site

1 reference