TNF-receptor-associated factor 6 Dmel_CG10961 (Q29809838)

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Protein found in Drosophila melanogaster

EP325
CG10961-PA
CG10961 gene product from transcript CG10961-RA
tumor necrosis factor receptor 2
TNF-receptor-associated factor 2
Traf6-PA
Traf6
TNF-receptor-associated factor 6

Language	Label	Description	Also known as
English	TNF-receptor-associated factor 6 Dmel_CG10961	Protein found in Drosophila melanogaster	EP325 CG10961-PA CG10961 gene product from transcript CG10961-RA tumor necrosis factor receptor 2 TNF-receptor-associated factor 2 Traf6-PA Traf6 TNF-receptor-associated factor 6

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

Zinc finger, RING/FYVE/PHD-type

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

TNF receptor-associated factor 6

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9W3I9

MATH/TRAF domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, protein family

1 reference

based on heuristic

inferred from protein domain or family

TNF receptor-associated factor 6, MATH domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Zinc finger, RING-type, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Drosophila melanogaster

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

tumor necrosis factor receptor binding

determination method

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method

protein binding

determination method

3 references

8 April 2019

Evolution of TNF signaling mechanisms: JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

8 April 2019

The Drosophila TNF receptor Grindelwald couples loss of cell polarity and neoplastic growth.

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

8 April 2019

ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

zinc ion binding

determination method

1 reference

8 April 2019

Comprehensively surveying structure and function of RING domains from Drosophila melanogaster

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

metal ion binding

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

ubiquitin-protein transferase activity

determination method

biological process

protein polyubiquitination

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

determination method

1 reference

8 April 2019

Roles of the JNK signaling pathway in Drosophila morphogenesis.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

Toll signaling pathway

determination method

1 reference

7 November 2018

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9W3I9&geneProductId=UniProtKB:Q9W3I9

determination method

determination method

1 reference

8 April 2019

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

positive regulation of autophagy

determination method

1 reference

8 April 2019

Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

protein ubiquitination

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

stress-activated protein kinase signaling cascade

determination method

1 reference

8 April 2019

Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

innate immune response

determination method

1 reference

8 April 2019

Discrete Functions of TRAF1 and TRAF2 in Drosophila melanogaster Mediated by c-Jun N-Terminal Kinase and NF-κB-Dependent Signaling Pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

regulation of defense response to virus

determination method

1 reference

8 April 2019

Antiviral autophagy restrictsRift Valley fever virus infection and is conserved from flies to mammals

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

defense response to Gram-negative bacterium

determination method

1 reference

8 April 2019

The Drosophila inhibitor of apoptosis protein DIAP2 functions in innate immunity and is essential to resist gram-negative bacterial infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

positive regulation of NF-kappaB transcription factor activity

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

protein K63-linked ubiquitination

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9W3I9

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

1 reference

ensembl Release 106

Ensembl protein ID

Sitelinks

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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