Hypoxia-inducible factor 1 CELE_F38A6.3 (Q29800119)

Myc-type, basic helix-loop-helix (bHLH) domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

PAS fold family

1 reference

based on heuristic

inferred from protein domain or family

PAS domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

10 April 2019

1 reference

10 April 2019

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

4 references

1 January 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

protein dimerization activity

IPI

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EGD2&geneProductId=UniProtKB:G5EGD2

16 July 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EGD2&geneProductId=UniProtKB:G5EGD2

16 July 2018

Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EGD2&geneProductId=UniProtKB:G5EGD2

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

Hydrogen sulfide increases hypoxia-inducible factor-1 activity independently of von Hippel-Lindau tumor suppressor-1 in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

phosphorelay signal transduction system

IBA

biological process

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

5 references

1 January 2018

CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

Dephosphorylation of cell cycle-regulated proteins correlates with anoxia-induced suspended animation in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 January 2018

CYSL-1 interacts with the O2-sensing hydroxylase EGL-9 to promote H2S-modulated hypoxia-induced behavioral plasticity in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

transcription, DNA-templated

IGI

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EGD2&geneProductId=UniProtKB:G5EGD2

regulation of transcription, DNA-templated

IEA

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

transcription by RNA polymerase II

IEA

1 reference

1 January 2018

A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

determination of adult lifespan

IEA

1 reference

1 January 2018

HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 reference

1 January 2018

HIF-1 is required for heat acclimation in the nematode Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

negative regulation of apoptotic process

1 reference

1 January 2018

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

positive regulation of transcription by RNA polymerase II

1 reference

16 July 2018

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=G5EGD2&geneProductId=UniProtKB:G5EGD2

Axotomy-induced HIF-serotonin signalling axis promotes axon regeneration in C. elegans

response to axon injury

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

cellular response to caloric restriction

1 reference

1 January 2018

HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

regulation of transcription by RNA polymerase II

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:G5EGD2

1 reference

Myc-type, basic helix-loop-helix (bHLH) domain

1 reference

stated in

PAS domain

1 reference

stated in