Death-promoting deoxyribonuclease CELE_K12H4.8 (Q29796816)

PAZ domain superfamily

1 reference

Ribonuclease III, endonuclease domain superfamily

1 reference

P-loop containing nucleoside triphosphate hydrolase

1 reference

Dicer dimerisation domain superfamily

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

Dicer dimerisation domain, protein family

1 reference

Double-stranded RNA-binding domain, protein family

1 reference

Helicase/UvrB, N-terminal domain, protein family

1 reference

Ribonuclease III domain, protein family

1 reference

PAZ domain, protein family

1 reference

found in taxon

Caenorhabditis elegans

1 reference

25 May 2022

1 reference

25 May 2022

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

DNA binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

RNA binding

helicase activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

nuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

endonuclease activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

ribonuclease III activity

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

3 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

16 July 2018

16 July 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

deoxyribonuclease I activity

1 reference

16 July 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

protein binding

3 references

1 January 2018

Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Functional proteomics reveals the biochemical niche of C. elegans DCR-1 in multiple small-RNA-mediated pathways

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

endoribonuclease activity, producing 5'-phosphomonoesters

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

metal ion binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

ribonuclease III activity

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

4 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

1 January 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

cell component

nucleus

1 reference

16 July 2018

A requirement for ERK-dependent Dicer phosphorylation in coordinating oocyte-to-embryo transition in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

cytoplasm

1 reference

16 July 2018

A requirement for ERK-dependent Dicer phosphorylation in coordinating oocyte-to-embryo transition in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

RISC complex

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

biological process

reproduction

1 reference

1 January 2018

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

DNA catabolic process, endonucleolytic

1 reference

1 January 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

nematode larval development

1 reference

1 January 2018

Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

apoptotic DNA fragmentation

IGI

1 reference

16 July 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

IGI

RNA processing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

RNA catabolic process

1 reference

1 January 2018

Caspase-dependent conversion of Dicer ribonuclease into a death-promoting deoxyribonuclease.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

apoptotic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

olfactory learning

1 reference

1 January 2018

Endogenous nuclear RNAi mediates behavioral adaptation to odor.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

rRNA catabolic process

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

production of siRNA involved in RNA interference

2 references

16 July 2018

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

16 July 2018

Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=P34529&geneProductId=UniProtKB:P34529

gene silencing

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

1 January 2018

gonad morphogenesis

1 reference

1 January 2018

A role for the RNase III enzyme DCR-1 in RNA interference and germ line development in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

regulation of development, heterochronic

1 reference

1 January 2018

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

RNA phosphodiester bond hydrolysis

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

RNA phosphodiester bond hydrolysis, endonucleolytic

1 reference

1 January 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

positive regulation of primary miRNA processing

1 reference

1 January 2018

Processing of primary microRNAs by the Microprocessor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

production of siRNA involved in RNA interference

Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

pre-miRNA processing

Processing of primary microRNAs by the Microprocessor complex

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P34529

1 reference

PAZ domain

1 reference

Helicase/UvrB, N-terminal

1 reference

Dicer dimerisation domain

1 reference

Helicase superfamily 1/2, ATP-binding domain

1 reference

Ribonuclease III domain

1 reference

Double-stranded RNA-binding domain

1 reference