Mitogen-activated protein kinase pmk-1 CELE_B0218.3 (Q29795543)

mitogen-activated protein (MAP) kinase p38-like

1 reference

Protein kinase domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Mitogen-activated protein (MAP) kinase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

Protein kinase, ATP binding site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

IEA

protein kinase activity

3 references

1 January 2018

1 January 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

4 references

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

16 July 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

16 July 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

2 references

transcription factor binding

1 reference

1 January 2018

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

5 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

GOA

curator

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

16 July 2018

A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

A conserved PMK-1/p38 MAPK is required in caenorhabditis elegans tissue-specific immune response to Yersinia pestis infection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

SEK-1 MAPKK mediates Ca2+ signaling to determine neuronal asymmetric development in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

response to reactive oxygen species

IGI

1 reference

1 January 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

IEP

response to superoxide

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

positive regulation of antimicrobial peptide production

IEP

1 reference

1 January 2018

The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

protein phosphorylation

3 references

1 January 2018

1 January 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

response to osmotic stress

1 reference

1 January 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

A Caenorhabditis elegans JNK signal transduction pathway regulates coordinated movement via type-D GABAergic motor neurons

hyperosmotic response

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

determination of adult lifespan

IGI

1 reference

1 January 2018

Distinct innate immune responses to infection and wounding in the C. elegans epidermis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway

programmed cell death

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

peptidyl-serine phosphorylation

IEA

behavioral response to nicotine

1 reference

1 January 2018

Twitchin kinase interacts with MAPKAP kinase 2 in Caenorhabditis elegans striated muscle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

intracellular signal transduction

1 reference

16 July 2018

Isolation and characterization of pmk-(1-3): three p38 homologs in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q17446&geneProductId=UniProtKB:Q17446

Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway

innate immune response

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

1 January 2018

Distinct innate immune responses to infection and wounding in the C. elegans epidermis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

positive regulation of transcription by RNA polymerase II

1 reference

1 January 2018

Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

defense response to Gram-negative bacterium

1 reference

1 January 2018

Conditioning protects C. elegans from lethal effects of enteropathogenic E. coli by activating genes that regulate lifespan and innate immunity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins.

response to nematicide

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

regulation of defense response to fungus

1 reference

1 January 2018

The pseudokinase NIPI-4 is a novel regulator of antimicrobial peptide gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

positive regulation of protein localization to nucleus

1 reference

1 January 2018

The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

positive regulation of defense response to bacterium

1 reference

1 January 2018

An age-dependent reversal in the protective capacities of JNK signaling shortens Caenorhabditis elegans lifespan

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

negative regulation of neuron death

IGI

1 reference

1 January 2018

Dysregulated LRRK2 signaling in response to endoplasmic reticulum stress leads to dopaminergic neuron degeneration in C. elegans

GOA

curator

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

regulation of gene expression

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

cellular response to organic substance

IBA

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q17446

mitogen-activated protein (MAP) kinase, conserved site

IBA

has part(s)

1 reference

protein kinase, ATP binding site

1 reference

protein kinase domain

1 reference