Bloom syndrome protein homolog CELE_T04A11.6 (Q29792853)

P-loop containing nucleoside triphosphate hydrolase

1 reference

Winged helix-like DNA-binding domain superfamily

1 reference

Winged helix DNA-binding domain superfamily

1 reference

HRDC-like superfamily

1 reference

Helicase superfamily 1/2, ATP-binding domain, protein family

1 reference

ATP-dependent DNA helicase RecQ, zinc-binding domain, protein family

1 reference

Helicase, C-terminal domain, protein family

1 reference

DEAD/DEAH box helicase

1 reference

HRDC domain, protein family

1 reference

RQC domain, protein family

1 reference

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

found in taxon

Caenorhabditis elegans

1 reference

5 December 2018

1 reference

5 December 2018

2 references

1 reference

1 January 2018

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

2 references

ATP-dependent activity, acting on DNA

1 reference

1 January 2018

Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

four-way junction helicase activity

IDA

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Coaction of DNA topoisomerase IIIalpha and a RecQ homologue during the germ-line mitosis in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

3'-5' DNA helicase activity

IPI

1 reference

1 January 2018

Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

four-way junction DNA binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

single-stranded DNA binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

ATP-dependent DNA/DNA annealing activity

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

protein homodimerization activity

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

forked DNA-dependent helicase activity

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

telomeric D-loop binding

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

8-hydroxy-2'-deoxyguanosine DNA binding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

intracellular anatomical structure

cell component

1 reference

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

DNA damage checkpoint signaling

biological process

1 reference

1 January 2018

Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Coaction of DNA topoisomerase IIIalpha and a RecQ homologue during the germ-line mitosis in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

resolution of meiotic recombination intermediates

1 reference

16 July 2018

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

double-strand break repair via homologous recombination

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

2 references

1 reference

16 July 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

cellular response to DNA damage stimulus

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

Coaction of DNA topoisomerase IIIalpha and a RecQ homologue during the germ-line mitosis in Caenorhabditis elegans.

chromosome segregation

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

reciprocal meiotic recombination

1 reference

1 January 2018

Multiple genetic pathways involving the Caenorhabditis elegans Bloom's syndrome genes him-6, rad-51, and top-3 are needed to maintain genome stability in the germ line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

determination of adult lifespan

IMP

1 reference

1 January 2018

Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

16 July 2018

Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

IMP

1 reference

16 July 2018

The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

1 reference

16 July 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

negative regulation of apoptotic process

1 reference

16 July 2018

Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

Coaction of DNA topoisomerase IIIalpha and a RecQ homologue during the germ-line mitosis in Caenorhabditis elegans.

chromosome organization

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

meiotic chromosome separation

1 reference

16 July 2018

Tests for parental imprinting in the nematode Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Coaction of DNA topoisomerase IIIalpha and a RecQ homologue during the germ-line mitosis in Caenorhabditis elegans.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

resolution of recombination intermediates

1 reference

16 July 2018

Characterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediates

http://www.ebi.ac.uk/QuickGO/annotations?protein=O18017&geneProductId=UniProtKB:O18017

regulation of cyclin-dependent protein serine/threonine kinase activity

IMP

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

resolution of meiotic recombination intermediates

DNA synthesis involved in DNA repair

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

double-strand break repair via nonhomologous end joining

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

mitotic G2 DNA damage checkpoint signaling

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

meiotic DNA double-strand break processing involved in reciprocal meiotic recombination

replication fork processing

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

G-quadruplex DNA unwinding

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

double-strand break repair via synthesis-dependent strand annealing

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

positive regulation of transcription, DNA-templated

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

negative regulation of mitotic recombination

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

protein complex oligomerization

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

protein homooligomerization

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

negative regulation of cell division

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

telomeric D-loop disassembly

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

cellular response to ionizing radiation

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

cellular response to hydroxyurea

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

regulation of DNA-dependent DNA replication

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

negative regulation of double-strand break repair via single-strand annealing

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

positive regulation of double-strand break repair via homologous recombination

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O18017

1 reference

DEAD/DEAH box helicase domain

1 reference

DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site

1 reference

Helicase superfamily 1/2, ATP-binding domain

1 reference

RQC domain

1 reference

HRDC domain

1 reference

ATP-dependent DNA helicase RecQ, zinc-binding domain

1 reference