Stochasticity in gene expression: from theories to phenotypes (Q29617360)

Europe PubMed Central

title

Stochasticity in gene expression: from theories to phenotypes (English)

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30 April 2017

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Kaern M

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30 April 2017

Elston TC

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2

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30 April 2017

Blake WJ

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30 April 2017

Collins JJ

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30 April 2017

language of work or name

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30 April 2017

publication date

June 2005

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30 April 2017

published in

Nature Reviews Genetics

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30 April 2017

volume

6

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page(s)

451-64

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30 April 2017

issue

6

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Stochastic focusing: fluctuation-enhanced sensitivity of intracellular regulation

30 April 2017

cites work

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Intrinsic noise in gene regulatory networks

1 May 2017

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Regulation of noise in the expression of a single gene

1 May 2017

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Intrinsic and extrinsic contributions to stochasticity in gene expression

1 May 2017

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Noise in eukaryotic gene expression

1 May 2017

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Control of stochasticity in eukaryotic gene expression

1 May 2017

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Cell signaling can direct either binary or graded transcriptional responses

1 May 2017

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Gene regulation at the single-cell level

1 May 2017

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Stochastic gene expression in a single cell

1 May 2017

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Engineering stability in gene networks by autoregulation

1 May 2017

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Positive feedback in eukaryotic gene networks: cell differentiation by graded to binary response conversion

1 May 2017

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Bacterial persistence as a phenotypic switch

1 May 2017

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Maintenance of stable heterochromatin domains by dynamic HP1 binding

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Modulation of heterochromatin protein 1 dynamics in primary Mammalian cells

1 May 2017

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

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Construction of a genetic toggle switch in Escherichia coli

1 May 2017

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A synthetic oscillatory network of transcriptional regulators

1 May 2017

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Robustness in simple biochemical networks

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Robustness in bacterial chemotaxis

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Network biology: understanding the cell's functional organization

1 May 2017

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Biological robustness

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ENZYME INDUCTION AS AN ALL-OR-NONE PHENOMENON

1 May 2017

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An outline of the pattern of bacterial generation times

31 March 2020

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Polyribosomes and unstable messenger RNA: a stochastic model of protein synthesis

31 March 2020

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Distribution of suboptimally induces -D-galactosidase in Escherichia coli. The enzyme content of individual cells.

31 March 2020

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Non-genetic individuality: chance in the single cell

31 March 2020

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Stochastic model of linear, continuous protein synthesis in bacterial populations

31 March 2020

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A model for the statistical fluctuations of protein numbers in a microbial population

31 March 2020

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A unified theory of gene expression

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A stochastic model for gene induction.

31 March 2020

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Induction mechanism of a single gene molecule: stochastic or deterministic?

31 March 2020

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Markovian Modeling of Gene-Product Synthesis

31 March 2020

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Stochastic mechanisms in gene expression

31 March 2020

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Mechanistic modeling of prokaryotic mRNA decay

31 March 2020

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Investigating autocatalytic gene expression systems through mechanistic modeling

31 March 2020

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Noise-based switches and amplifiers for gene expression

31 March 2020

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Circadian clocks limited by noise

31 March 2020

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Stochasticity in transcriptional regulation: origins, consequences, and mathematical representations

31 March 2020

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The effect of transcription and translation initiation frequencies on the stochastic fluctuations in prokaryotic gene expression.

31 March 2020

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Noise in a minimal regulatory network: plasmid copy number control

31 March 2020

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Robustness of circadian rhythms with respect to molecular noise

31 March 2020

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Fifteen minutes of fim: control of type 1 pili expression in E. coli

31 March 2020

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Attenuation of noise in ultrasensitive signaling cascades

31 March 2020

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Mechanisms of noise-resistance in genetic oscillators

31 March 2020

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On the relation between fluctuation and response in biological systems

31 March 2020

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Stochastic gene expression as a many-body problem

31 March 2020

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Frequency domain analysis of noise in autoregulated gene circuits.

31 March 2020

1 reference

Fluctuating reaction rates and their application to problems of gene expression.

31 March 2020

1 reference

Summing up the noise in gene networks

31 March 2020

1 reference

Fluctuations in transcription factor binding can explain the graded and binary responses observed in inducible gene expression

31 March 2020

1 reference

Frequency domain chemical Langevin analysis of stochasticity in gene transcriptional regulation.

31 March 2020

1 reference

Intrinsic and external noise in an auto-regulatory genetic network.

31 March 2020

1 reference

Multivariate analysis of noise in genetic regulatory networks.

31 March 2020

1 reference

Control of internal and external noise in genetic regulatory networks

31 March 2020

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Graded and binary responses in stochastic gene expression

31 March 2020

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Noise-reduction through interaction in gene expression and biochemical reaction processes.

31 March 2020

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Efficient attenuation of stochasticity in gene expression through post-transcriptional control.

31 March 2020

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Noisy signal amplification in ultrasensitive signal transduction

31 March 2020

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Sampling Rare Switching Events in Biochemical Networks

31 March 2020

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Optimal path to epigenetic switching.

31 March 2020

1 reference

Stochastic simulation of the mammalian circadian clock

31 March 2020

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Morphogen gradient from a noisy source

31 March 2020

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Stochastic gene expression during cell differentiation: order from disorder?

31 March 2020

1 reference

Transcription of individual genes in eukaryotic cells occurs randomly and infrequently

31 March 2020

1 reference

Notch signalling in development: on equivalence groups and asymmetric developmental potential

31 March 2020

1 reference

Stochastic, stage-specific mechanisms account for the variegation of a human globin transgene

31 March 2020

1 reference

Independent regulation of the two Pax5 alleles during B-cell development.

31 March 2020

1 reference

p53-dependent transcription can exhibit both on/off and graded response after genotoxic stress

31 March 2020

1 reference

Ultrasensitivity and noise propagation in a synthetic transcriptional cascade.

31 March 2020

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Noise propagation in gene networks

31 March 2020

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Prediction and measurement of an autoregulatory genetic module

31 March 2020

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Comparison of classical and autogenous systems of regulation in inducible operons

31 March 2020

1 reference

Control, exploitation and tolerance of intracellular noise

31 March 2020

1 reference

Oscillatory expression of Hes1, p53, and NF-kappaB driven by transcriptional time delays.

31 March 2020

1 reference

Generation of oscillations by the p53-Mdm2 feedback loop: a theoretical and experimental study

31 March 2020

1 reference

Dynamics of the p53-Mdm2 feedback loop in individual cells

31 March 2020

1 reference

Periodic notch inhibition by lunatic fringe underlies the chick segmentation clock.

31 March 2020

1 reference

The segmentation clock: converting embryonic time into spatial pattern

31 March 2020

1 reference

Autoinhibition with transcriptional delay: a simple mechanism for the zebrafish somitogenesis oscillator.

31 March 2020

1 reference

A Notch feeling of somite segmentation and beyond

31 March 2020

1 reference

The consequences of imperfect mixing in autocatalytic chemical and biological systems

31 March 2020

1 reference

Multistability in the lactose utilization network of Escherichia coli

31 March 2020

1 reference

Enhancement of cellular memory by reducing stochastic transitions

31 March 2020

1 reference

Noise minimization in eukaryotic gene expression

31 March 2020

1 reference

It's a noisy business! Genetic regulation at the nanomolar scale

31 March 2020

1 reference

Programmed death in bacteria

31 March 2020

1 reference

Stress and the single cell: intrapopulation diversity is a mechanism to ensure survival upon exposure to stress

31 March 2020

1 reference

Stochastic gene expression in fluctuating environments

31 March 2020

1 reference

Stress and how bacteria cope with death and survival.

31 March 2020

1 reference

Stochastic processes influence stationary-phase decisions in Bacillus subtilis

31 March 2020

1 reference

Microbiology. Noninherited resistance to antibiotics

31 March 2020

1 reference

The initiation of hepatocyte-specific gene expression within embryonic hepatocytes is a stochastic event

31 March 2020

1 reference

Evolution of cell lineage

31 March 2020

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Evidence that hematopoiesis may be a stochastic process in vivo

31 March 2020

1 reference

A Darwinian theory for the origin of cellular differentiation.

31 March 2020

1 reference

How the mouse got its spots.

31 March 2020

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The origin of hematopoietic cell type diversity

31 March 2020

1 reference

Refinement of gene expression patterns in the early Xenopus embryo

31 March 2020

1 reference

Self-organization vs Watchmaker: stochastic gene expression and cell differentiation

31 March 2020

1 reference

Modeling embryogenesis and cancer: an approach based on an equilibrium between the autostabilization of stochastic gene expression and the interdependence of cells for proliferation.

31 March 2020

1 reference

Polymerase chain reaction-aided genomic sequencing of an X chromosome-linked CpG island: methylation patterns suggest clonal inheritance, CpG site autonomy, and an explanation of activity state stability

31 March 2020

1 reference

DNA methylation density influences the stability of an epigenetic imprint and Dnmt3a/b-independent de novo methylation.

31 March 2020

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Fluctuation of chromatin unfolding associated with variation in the level of gene expression

31 March 2020

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Insulator dynamics and the setting of chromatin domains.

31 March 2020

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Illegitimate transcription: transcription of any gene in any cell type

31 March 2020

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Gene number, noise reduction and biological complexity

31 March 2020

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Gene number, methylation and biological complexity.

31 March 2020

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Modulation of a transcription factor counteracts heterochromatic gene silencing in Drosophila.

31 March 2020

1 reference

Transcription factor dosage affects changes in higher order chromatin structure associated with activation of a heterochromatic gene

31 March 2020

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Transcription factor haploinsufficiency: when half a loaf is not enough

31 March 2020

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Modeling stochastic gene expression: implications for haploinsufficiency

31 March 2020

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A genetic switch in pancreatic beta-cells: implications for differentiation and haploinsufficiency.

31 March 2020

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Increased noise as an effect of haploinsufficiency of the tumor-suppressor gene neurofibromatosis type 1 in vitro

31 March 2020

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Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation

31 March 2020

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Simultaneously monitoring gene expression kinetics and genetic noise in single cells by optical well arrays.

31 March 2020

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The future is noisy: the role of spatial fluctuations in genetic switching

31 March 2020

1 reference

High local protein concentrations at promoters: strategies in prokaryotic and eukaryotic cells

31 March 2020

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Epigenes: design and construction of new hereditary units

31 March 2020

1 reference

An engineered epigenetic transgene switch in mammalian cells

31 March 2020

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Programmable cells: interfacing natural and engineered gene networks

31 March 2020

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Development of genetic circuitry exhibiting toggle switch or oscillatory behavior in Escherichia coli

31 March 2020

1 reference

Constructive effects of fluctuations in genetic and biochemical regulatory systems.

31 March 2020

1 reference

Programmed population control by cell-cell communication and regulated killing.

31 March 2020

1 reference

Noise in gene expression as the source of non-genetic individuality in the chemotactic response of Escherichia coli.

31 March 2020

1 reference

From molecular noise to behavioural variability in a single bacterium.

31 March 2020

1 reference

Robustness of cellular functions

31 March 2020

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Noise, delays, robustness, canalization and all that

31 March 2020

1 reference

Robust control in bacterial regulatory circuits

31 March 2020

1 reference

Response of complex networks to stimuli

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15883588

31 March 2020

Identifiers

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1042111

1014958319

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1042111

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=15883588

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017