Transglutaminase 2 (Q29523710)

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mammalian protein found in Rattus norvegicus

tissue-type transglutaminase
Tgm2
glutamine gamma-glutamyltransferase 2
protein-glutamine gamma-glutamyltransferase 2
transglutaminase 2, C polypeptide

Language	Label	Description	Also known as
English	Transglutaminase 2	mammalian protein found in Rattus norvegicus	tissue-type transglutaminase Tgm2 glutamine gamma-glutamyltransferase 2 protein-glutamine gamma-glutamyltransferase 2 transglutaminase 2, C polypeptide

Statements

1 reference

10 February 2021

UniProt protein ID

Transglutaminase-like superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Protein-glutamine gamma-glutamyltransferase, animal

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Transglutaminase, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Immunoglobulin E-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Papain-like cysteine peptidase superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q6P6R6

Transglutaminase, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transglutaminase-like family

1 reference

based on heuristic

inferred from protein domain or family

Transglutaminase, C-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Transglutaminase, active site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

10 February 2021

UniProt protein ID

1 reference

10 February 2021

UniProt protein ID

molecular function

protein-glutamine gamma-glutamyltransferase activity

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

protein binding

determination method

1 reference

9 May 2019

A novel follicle-stimulating hormone-induced G alpha h/phospholipase C-delta1 signaling pathway mediating rat sertoli cell Ca2+-influx

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

determination method

1 reference

9 May 2019

Functional coupling of rat myometrial alpha 1-adrenergic receptors to Gh alpha/tissue transglutaminase 2 during pregnancy

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

determination method

1 reference

9 May 2019

Mitochondrial aconitase is a transglutaminase 2 substrate: transglutamination is a probable mechanism contributing to high-molecular-weight aggregates of aconitase and loss of aconitase activity in Huntington disease brain

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

protein domain specific binding

determination method

1 reference

9 May 2019

Modulation of intracellular Ca(2+) via alpha(1B)-adrenoreceptor signaling molecules, G alpha(h) (transglutaminase II) and phospholipase C-delta 1

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

metal ion binding

determination method

1 reference

9 May 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

determination method

1 reference

14 February 2019

Mitochondrial aconitase is a transglutaminase 2 substrate: transglutamination is a probable mechanism contributing to high-molecular-weight aggregates of aconitase and loss of aconitase activity in Huntington disease brain

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

plasma membrane

determination method

1 reference

9 May 2019

Functional coupling of rat myometrial alpha 1-adrenergic receptors to Gh alpha/tissue transglutaminase 2 during pregnancy

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

determination method

2 references

biological process

blood vessel remodeling

determination method

1 reference

9 May 2019

Small artery remodeling depends on tissue-type transglutaminase

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

peptide cross-linking

determination method

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine

determination method

1 reference

9 May 2019

Mitochondrial aconitase is a transglutaminase 2 substrate: transglutamination is a probable mechanism contributing to high-molecular-weight aggregates of aconitase and loss of aconitase activity in Huntington disease brain

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

positive regulation of apoptotic process

determination method

1 reference

9 May 2019

Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

positive regulation of I-kappaB kinase/NF-kappaB signaling

determination method

1 reference

9 May 2019

Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

positive regulation of smooth muscle cell proliferation

determination method

1 reference

9 May 2019

Functional coupling of rat myometrial alpha 1-adrenergic receptors to Gh alpha/tissue transglutaminase 2 during pregnancy

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

positive regulation of inflammatory response

determination method

1 reference

9 May 2019

Transglutaminase 2 induces nuclear factor-kappaB activation via a novel pathway in BV-2 microglia

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

protein homooligomerization

determination method

positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway

determination method

1 reference

9 May 2019

Modulation of intracellular Ca(2+) via alpha(1B)-adrenoreceptor signaling molecules, G alpha(h) (transglutaminase II) and phospholipase C-delta 1

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q6P6R6

determination method

Identifiers

RefSeq protein ID

1 reference

7 March 2021

1 reference

7 March 2021

1 reference

7 March 2021

UniProt protein ID

1 reference

10 February 2021

UniProt protein ID

Sitelinks

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Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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