Thrombospondin 1 (Q29517729)

Concanavalin A-like lectin/glucanase domain superfamily

1 reference

Thrombospondin type-1 (TSP1) repeat superfamily

1 reference

thrombospondin-1

1 reference

Thrombospondin, C-terminal domain, protein family

1 reference

Laminin G domain, protein family

1 reference

VWFC domain, protein family

1 reference

EGF-like calcium-binding domain, protein family

1 reference

EGF-like domain, protein family

1 reference

Thrombospondin, type 3-like repeat, protein family

1 reference

EGF-like, conserved site, protein family

1 reference

Thrombospondin type-1 (TSP1) repeat, protein family

1 reference

Thrombospondin, type 3 repeat, protein family

1 reference

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

1 reference

25 May 2022

1 reference

25 May 2022

2 references

1 reference

14 February 2019

transforming growth factor beta binding

IEA

2 references

14 February 2019

Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

14 February 2019

Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

extracellular matrix binding

IDA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

3 references

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

1 January 2018

Purinergic signaling induces thrombospondin-1 expression in astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

1 reference

14 February 2019

Purinergic signaling induces thrombospondin-1 expression in astrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

platelet alpha granule

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

collagen-containing extracellular matrix

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

response to mechanical stimulus

IEA

1 reference

14 February 2019

Capillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

negative regulation of angiogenesis

IMP

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

14 February 2019

Capillary sprout endothelial cells exhibit a CD36 low phenotype: regulation by shear stress and vascular endothelial growth factor-induced mechanism for attenuating anti-proliferative thrombospondin-1 signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

positive regulation of transforming growth factor beta receptor signaling pathway

1 reference

1 January 2018

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q71SA3&geneProductId=UniProtKB:Q71SA3

positive regulation of transforming growth factor beta1 production

1 reference

14 February 2019

Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36

GOA

curator

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

Androgens repress the expression of the angiogenesis inhibitor thrombospondin-1 in normal and neoplastic prostate

IDA

response to testosterone

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

cellular response to tumor necrosis factor

IEP

1 reference

14 February 2019

Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

cellular response to growth factor stimulus

IEP

1 reference

14 February 2019

Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

positive regulation of transforming growth factor beta production

IEP

1 reference

14 February 2019

A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q71SA3

IMP

inflammatory response

1 reference

14 February 2019

Thrombospondin type-1 (TSP1) repeat

IEA

has part(s)

1 reference

EGF-like calcium-binding domain

1 reference

Thrombospondin, C-terminal

1 reference

Thrombospondin, type 3-like repeat

1 reference

EGF-like domain

1 reference

Thrombospondin, type 3 repeat

1 reference

EGF-like, conserved site

1 reference

VWFC domain

1 reference

Laminin G domain

1 reference