Lactose digestion and the evolutionary genetics of lactase persistence (Q29039068)

27 March 2017

Mark G. Thomas

4

0 references

author name string

Catherine J. E. Ingram

1

1 reference

27 March 2017

Charlotte A. Mulcare

2

1 reference

27 March 2017

Yuval Itan

3

1 reference

27 March 2017

Dallas M. Swallow

5

1 reference

27 March 2017

publication date

26 November 2008

1 reference

27 March 2017

1 reference

27 March 2017

volume

124

1 reference

27 March 2017

page(s)

579-591

1 reference

27 March 2017

issue

6

1 reference

https://scigraph.springernature.com/pub.10.1007/s00439-008-0593-6

27 March 2017

exact match

0 references

cites work

Cow's milk allergy: a complex disorder

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

The bioavailability of dietary calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

Expression of lactase-phlorizin hydrolase in sheep is regulated at the RNA level

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

Lactose absorption in patients with ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

Regulation of lactase-phlorizin hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-008-0593-6

Mosaic regulation of lactase in human adult-type hypolactasia

21 January 2018

1 reference

12 December 2020

Impact of O-glycosylation on the function of human intestinal lactase-phlorizin hydrolase. Characterization of glycoforms varying in enzyme activity and localization of O-glycoside addition

1 reference

12 December 2020

Expression and intracellular transport of microvillus membrane hydrolases in human intestinal epithelial cells

1 reference

12 December 2020

A randomized trial of Lactobacillus acidophilus BG2FO4 to treat lactose intolerance

1 reference

12 December 2020

Transport, function, and sorting of lactase-phlorizin hydrolase in Madin-Darby canine kidney cells.

1 reference

12 December 2020

Transcriptional regulation of pig lactase-phlorizin hydrolase: involvement of HNF-1 and FREACs

1 reference

12 December 2020

T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro

1 reference

12 December 2020

Gene-culture coevolution between cattle milk protein genes and human lactase genes

1 reference

12 December 2020

Positive natural selection in the human lineage

1 reference

12 December 2020

Primary lactase deficiency and past malarial endemicity in Sardinia.

1 reference

12 December 2020

The lactase persistence/non-persistence polymorphism is controlled by a cis-acting element.

1 reference

12 December 2020

Systemic lactose intolerance: a new perspective on an old problem

1 reference

12 December 2020

Lactose nutrition and natural selection.

1 reference

12 December 2020

The T allele of a single-nucleotide polymorphism 13.9 kb upstream of the lactase gene (LCT) (C-13.9kbT) does not predict or cause the lactase-persistence phenotype in Africans

1 reference

12 December 2020

Improved clinical tolerance to chronic lactose ingestion in subjects with lactose intolerance: a placebo effect?

1 reference

12 December 2020

Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development

1 reference

12 December 2020

Gene-dosage effect on intestinal lactase activity demonstrated in vivo

1 reference

12 December 2020

GATA family transcription factors activate lactase gene promoter in intestinal Caco-2 cells

1 reference

12 December 2020

Folding of human intestinal lactase-phlorizin hydrolase

1 reference

12 December 2020

Genetic aetiology of lactose intolerance

1 reference

12 December 2020

Lactase polymorphism in adult British natives: estimating allele frequencies by enzyme assays in autopsy samples.

1 reference

12 December 2020

Lactase persistence DNA variant enhances lactase promoter activity in vitro: functional role as a cis regulatory element

1 reference

12 December 2020

The causal element for the lactase persistence/non-persistence polymorphism is located in a 1 Mb region of linkage disequilibrium in Europeans.

1 reference

12 December 2020

Mosaic pattern of lactase expression by villous enterocytes in human adult-type hypolactasia

1 reference

12 December 2020

The prosequence of human lactase-phlorizin hydrolase modulates the folding of the mature enzyme

1 reference

12 December 2020

Control of lactase in human adult-type hypolactasia and in weaning rabbits and rats

1 reference

12 December 2020

Differential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.

1 reference

12 December 2020

Genetic predisposition for adult lactose intolerance and relation to diet, bone density, and bone fractures.

1 reference

12 December 2020

The geographic hypothesis and lactose malabsorption. A weighing of the evidence

1 reference

12 December 2020

Identification of a variant associated with adult-type hypolactasia

1 reference

12 December 2020

The genetic variant of lactase persistence C (−13910) T as a risk factor for type I and II diabetes in the Finnish population

1 reference

12 December 2020

Lactase haplotype frequencies in Caucasians: association with the lactase persistence/non-persistence polymorphism

1 reference

12 December 2020

1 kb of the lactase-phlorizin hydrolase promoter directs post-weaning decline and small intestinal-specific expression in transgenic mice

1 reference

12 December 2020

Lactase gene promoter fragments mediate differential spatial and temporal expression patterns in transgenic mice.

1 reference

12 December 2020

Lactose intolerance-a confusing clinical diagnosis

1 reference

12 December 2020

Fecal hydrogen production and consumption measurements. Response to daily lactose ingestion by lactose maldigesters

1 reference

12 December 2020

Regulation of Intestine-specific Spatiotemporal Expression by the Rat Lactase Promoter

1 reference

12 December 2020

Interaction between the homeodomain proteins Cdx2 and HNF1alpha mediates expression of the lactase-phlorizin hydrolase gene

1 reference

12 December 2020

A study of lactose absorption capacity in twins

1 reference

12 December 2020

Coordinate expression of lactase-phlorizin hydrolase mRNA and enzyme levels in rat intestine during development

1 reference

12 December 2020

Genetic signatures of strong recent positive selection at the lactase gene

1 reference

12 December 2020

Did malaria select for primary adult lactase deficiency?

1 reference

12 December 2020

Distribution of the lactase phenotypes in the population of the Democratic Republic of the Sudan

1 reference

12 December 2020

Milk, milk products and lactose intake and ovarian cancer risk: a meta-analysis of epidemiological studies

1 reference

12 December 2020

The homeodomain protein Cdx2 regulates lactase gene promoter activity during enterocyte differentiation

1 reference

12 December 2020

Regulation of intestinal lactase in adult hypolactasia

1 reference

12 December 2020

Clinical picture of hypolactasia and lactose intolerance.

1 reference

12 December 2020

Hepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivo

1 reference

12 December 2020

Darwin's illness revealed

1 reference

12 December 2020

Common polymorphism in a highly variable region upstream of the human lactase gene affects DNA-protein interactions

1 reference

12 December 2020

INTESTINAL LACTASE DEFICIENCY AND LACTOSE INTOLERANCE IN ADULTS. PRELIMINARY REPORT

1 reference

12 December 2020

High intestinal lactase concentrations in adult Arbs in Saudi Arabia.

1 reference

12 December 2020

Independent introduction of two lactase-persistence alleles into human populations reflects different history of adaptation to milk culture

1 reference

12 December 2020

Biogenesis of intestinal lactase-phlorizin hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes

1 reference

12 December 2020

DNA test for hypolactasia premature.

1 reference

12 December 2020

The acceptability of milk and milk products in populations with a high prevalence of lactose intolerance

1 reference

12 December 2020

Hydrogen breath testing versus LCT genotyping for the diagnosis of lactose intolerance: a matter of age?

1 reference

12 December 2020

Lactase haplotype diversity in the Old World

1 reference

12 December 2020

DNA polymorphisms in the lactase gene. Linkage disequilibrium across the 70-kb region

1 reference

12 December 2020

A genetic test which can be used to diagnose adult-type hypolactasia in children

1 reference

12 December 2020

A stochastic model of gene-culture coevolution suggested by the "culture historical hypothesis" for the evolution of adult lactose absorption in humans

1 reference

12 December 2020

Genetically defined adult-type hypolactasia and self-reported lactose intolerance as risk factors of osteoporosis in Finnish postmenopausal women

1 reference

12 December 2020

Lactase persistence/non-persistence variants, C/T_13910 and G/A_22018, as a diagnostic tool for lactose intolerance in IBS patients

1 reference

12 December 2020

Maturation of human intestinal lactase-phlorizin hydrolase: generation of the brush border form of the enzyme involves at least two proteolytic cleavage steps

1 reference

12 December 2020

A novel polymorphism associated with lactose tolerance in Africa: multiple causes for lactase persistence?

1 reference

12 December 2020

Lactose tolerance in adult Jordanian Arabs

1 reference

12 December 2020

Molecular basis of lactase levels in adult humans

1 reference

12 December 2020

The T/G 13915 variant upstream of the lactase gene (LCT) is the founder allele of lactase persistence in an urban Saudi population

1 reference

12 December 2020

Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine

1 reference

12 December 2020

Structure of the chromosomal gene and cDNAs coding for lactase-phlorizin hydrolase in humans with adult-type hypolactasia or persistence of lactase

1 reference

12 December 2020

ISOLATED INTESTINAL LACTASE DEFICIENCY IN THE ADULT

1 reference

12 December 2020

Evaluation of a novel reverse-hybridization StripAssay for typing DNA variants useful in diagnosis of adult-type hypolactasia

1 reference

12 December 2020

Primary adult lactose intolerance and the milking habit: a problem in biologic and cultural interrelations. II. A culture historical hypothesis

1 reference

12 December 2020

An upstream polymorphism associated with lactase persistence has increased enhancer activity

1 reference

12 December 2020

High prevalence of lactose absorbers in Northern Sardinian patients with type 1 and type 2 diabetes mellitus

1 reference

12 December 2020

Tolerance to the daily ingestion of two cups of milk by individuals claiming lactose intolerance

1 reference

12 December 2020

Genetic variant of lactase-persistent C/T-13910 is associated with bone fractures in very old age.

1 reference

12 December 2020

Evidence of still-ongoing convergence evolution of the lactase persistence T-13910 alleles in humans

1 reference

12 December 2020

Absence of the lactase-persistence-associated allele in early Neolithic Europeans

1 reference

12 December 2020

Prospective Comparison of Indirect Methods for Detecting Lactase Deficiency

1 reference

12 December 2020

Convergent adaptation of human lactase persistence in Africa and Europe

1 reference

12 December 2020

Colonic adaptation to daily lactose feeding in lactose maldigesters reduces lactose intolerance

1 reference

12 December 2020

Pitfalls in LightCycler diagnosis of the single-nucleotide polymorphism 13.9 kb upstream of the lactase gene that is associated with adult-type hypolactasia.

1 reference

12 December 2020

The biosynthetic basis of adult lactase deficiency

1 reference

12 December 2020

The International HapMap Project

1 reference

12 December 2020

The inheritance of selective adult-type lactose malabsorption

1 reference

12 December 2020

Complex regulation of the lactase-phlorizin hydrolase promoter by GATA-4.

1 reference

12 December 2020

A novel proximal -13914G>A base replacement in the vicinity of the common-13910T/C lactase gene variation results in an atypical LightCycler melting curve in testing with the MutaREAL Lactase test.

1 reference

12 December 2020

A comparison of calcium, vitamin D, or both for nutritional rickets in Nigerian children.

1 reference

12 December 2020

Evaluation of a new DNA test compared with the lactose hydrogen breath test for the diagnosis of lactase non-persistence

1 reference

12 December 2020

Beja and Nilotes: nomadic pastoralist groups in the Sudan with opposite distributions of the adult lactase phenotypes

1 reference

12 December 2020

Phylogenetic analysis of the evolution of lactose digestion in adults.

1 reference

12 December 2020

Microsatellite variation and evolution of human lactase persistence

1 reference

12 December 2020

10.1007/S00439-008-0593-6

Identifiers

DOI

2 references

27 March 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

3952235

1015747323

0 references

3952235

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference