Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue (Q28833485)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26869437%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue (English)

1 reference

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7 March 2020

1 reference

1 reference

1

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7 March 2020

Takeo Nakanishi

6

1 reference

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7 March 2020

author name string

Jing Sun

2

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7 March 2020

Yasuhiro Tsume

3

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7 March 2020

Hao Xu

4

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7 March 2020

Tomoka Gose

5

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7 March 2020

Ikumi Tamai

7

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7 March 2020

John Hilfinger

8

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7 March 2020

Elke Lipka

9

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7 March 2020

Gordon L Amidon

10

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7 March 2020

language of work or name

English

0 references

publication date

1 February 2016

1 reference

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Journal of Pharmaceutical Sciences

7 March 2020

published in

1 reference

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7 March 2020

volume

105

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7 March 2020

page(s)

925-934

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7 March 2020

issue

2

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Molecular Basis of Prodrug Activation by Human Valacyclovirase, an -Amino Acid Ester Hydrolase

7 March 2020

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3 June 2018

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3 June 2018

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Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza

3 June 2018

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Enhancing the intestinal membrane permeability of zanamivir: a carrier mediated prodrug approach

3 June 2018

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Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir

3 June 2018

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Enabling the intestinal absorption of highly polar antiviral agents: ion-pair facilitated membrane permeation of zanamivir heptyl ester and guanidino oseltamivir

3 June 2018

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Enhancing the intestinal absorption of molecules containing the polar guanidino functionality: a double-targeted prodrug approach

3 June 2018

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Chemical and enzymatic stability of amino acid prodrugs containing methoxy, ethoxy and propylene glycol linkers

3 June 2018

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Vaccine production capacity for seasonal and pandemic (H1N1) 2009 influenza

3 June 2018

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Developing new antiviral agents for influenza treatment: what does the future hold?

3 June 2018

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Synthesis and anti-influenza activities of carboxyl alkoxyalkyl esters of 4-guanidino-Neu5Ac2en (zanamivir).

3 June 2018

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Treatment of respiratory virus infections

3 June 2018

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Identification of a human valacyclovirase: biphenyl hydrolase-like protein as valacyclovir hydrolase

3 June 2018

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Transport of valganciclovir, a ganciclovir prodrug, via peptide transporters PEPT1 and PEPT2.

3 June 2018

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Clinical pharmacokinetics of the prodrug oseltamivir and its active metabolite Ro 64-0802.

3 June 2018

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Direct evidence for peptide transporter (PepT1)-mediated uptake of a nonpeptide prodrug, valacyclovir.

3 June 2018

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3 June 2018

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3 June 2018

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Increasing oral absorption of polar neuraminidase inhibitors: a prodrug transporter approach applied to oseltamivir analogue

3 June 2018

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The intestinal absorption of a prodrug of the mGlu2/3 receptor agonist LY354740 is mediated by PEPT1: in situ rat intestinal perfusion studies

26 November 2018

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26 November 2018

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26 November 2018

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Crossref

https://api.crossref.org/works/10.1016%2FJ.XPHS.2015.11.036

Comparison of human duodenum and Caco-2 gene expression profiles for 12,000 gene sequences tags and correlation with permeability of 26 drugs

7 January 2021

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Crossref

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10.1016/J.XPHS.2015.11.036

7 January 2021

Identifiers

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release_gbuwa2somfbvbnofngbz2stwwy

7 March 2020

Fatcat ID

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7 March 2020

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