DDK dependent regulation of TOP2A at centromeres revealed by a chemical genetics approach (Q28822095)

1

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10 June 2020

Michael D Rainey

5

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10 June 2020

Angela Bachi

7

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10 June 2020

Corrado Santocanale

8

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10 June 2020

author name string

Guan-Nan Wang

2

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10 June 2020

Jennifer Fitzgerald

3

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10 June 2020

Huong Quachthithu

4

1 reference

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10 June 2020

Angela Cattaneo

6

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10 June 2020

language of work or name

English

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publication date

14 October 2016

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published in

Nucleic Acids Research

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10 June 2020

volume

44

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10 June 2020

issue

18

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10 June 2020

page(s)

8786-8798

1 reference

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Creative Commons Attribution-NonCommercial 4.0 International

10 June 2020

copyright license

start time

11 November 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

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Crystal structure of human CDC7 kinase in complex with its activator DBF4

16 March 2017

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16 March 2017

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Saccharomyces cerevisiae Dbf4 Has Unique Fold Necessary for Interaction with Rad53 Kinase

16 March 2017

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DNA topoisomerases and their poisoning by anticancer and antibacterial drugs

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Topoisomerase IIalpha controls the decatenation checkpoint

16 March 2017

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Dbf4-dependent CDC7 kinase links DNA replication to the segregation of homologous chromosomes in meiosis I.

16 March 2017

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Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombination

16 March 2017

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The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen

16 March 2017

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Identification of Mcm2 phosphorylation sites by S-phase-regulating kinases

16 March 2017

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Dual role of the Cdc7-regulatory protein Dbf4 during yeast meiosis.

16 March 2017

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A statistical model for identifying proteins by tandem mass spectrometry

16 March 2017

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An N-terminal domain of Dbf4p mediates interaction with both origin recognition complex (ORC) and Rad53p and can deregulate late origin firing

16 March 2017

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Empirical statistical model to estimate the accuracy of peptide identifications made by MS/MS and database search

16 March 2017

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Drf1, a novel regulatory subunit for human Cdc7 kinase

16 March 2017

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Mammalian Cdc7-Dbf4 protein kinase complex is essential for initiation of DNA replication

16 March 2017

1 reference

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A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells

16 March 2017

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Identification and characterization of a human protein kinase related to budding yeast Cdc7p

16 March 2017

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A chemical switch for inhibitor-sensitive alleles of any protein kinase

16 March 2017

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Cdc7-Dbf4 is a gene-specific regulator of meiotic transcription in yeast

7 April 2017

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Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeast

9 May 2017

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TOPBP1 recruits TOP2A to ultra-fine anaphase bridges to aid in their resolution

9 May 2017

1 reference

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Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome

3 June 2018

1 reference

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Temporospatial coordination of meiotic DNA replication and recombination via DDK recruitment to replisomes.

3 June 2018

1 reference

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DNA replication and oncogene-induced replicative stress

3 June 2018

1 reference

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Activation of the prereplication complex is blocked by mimosine through reactive oxygen species-activated ataxia telangiectasia mutated (ATM) protein without DNA damage

3 June 2018

1 reference

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Causes and consequences of replication stress

3 June 2018

1 reference

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ATR-Chk1-APC/CCdh1-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

3 June 2018

1 reference

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Cdc7-dependent and -independent phosphorylation of Claspin in the induction of the DNA replication checkpoint

3 June 2018

1 reference

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Inhibition of DNA damage-induced apoptosis through Cdc7-mediated stabilization of Tob.

3 June 2018

1 reference

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Control over DNA replication in time and space

3 June 2018

1 reference

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Labeling and identification of direct kinase substrates

3 June 2018

1 reference

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Bloom's syndrome and PICH helicases cooperate with topoisomerase IIα in centromere disjunction before anaphase

3 June 2018

1 reference

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Dbf4 is direct downstream target of ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related (ATR) protein to regulate intra-S-phase checkpoint

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Hsk1- and SCF(Pof3)-dependent proteolysis of S. pombe Ams2 ensures histone homeostasis and centromere function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Histone H3 Thr 45 phosphorylation is a replication-associated post-translational modification in S. cerevisiae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Strategies for the identification of kinase substrates using analog-sensitive kinases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Cdc7 kinase - a new target for drug development.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

DNA topoisomerase II and its growing repertoire of biological functions.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Cdc7-Drf1 kinase links chromosome cohesion to the initiation of DNA replication in Xenopus egg extracts.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Covalent capture of kinase-specific phosphopeptides reveals Cdk1-cyclin B substrates.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Cell cycle regulation of DNA replication.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Using chemical genetics and ATP analogues to dissect protein kinase function

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

A semisynthetic epitope for kinase substrates.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Phosphorylation of MCM4 by Cdc7 kinase facilitates its interaction with Cdc45 on the chromatin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Cdc7-Dbf4 phosphorylates MCM proteins via a docking site-mediated mechanism to promote S phase progression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Bio-orthogonal affinity purification of direct kinase substrates

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Etoposide: discovery and medicinal chemistry

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Human topoisomerase IIalpha: targeting to subchromosomal sites of activity during interphase and mitosis.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

The spatio-temporal organization of DNA replication sites is identical in primary, immortalized and transformed mammalian cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Rapid exchange of mammalian topoisomerase II alpha at kinetochores and chromosome arms in mitosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Chemical genetic approaches for the elucidation of signaling pathways

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Replication timing of DNA sequences associated with human centromeres and telomeres

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Rapid generation of chromosome-specific alphoid DNA probes using the polymerase chain reaction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Cdc7 is an active kinase in human cancer cells undergoing replication stress.

3 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW626

Cdc7 kinase mediates Claspin phosphorylation in DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW626

Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW626

Bipartite binding of a kinase activator activates Cdc7-related kinase essential for S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW626

In vivo dual cross-linking for identification of indirect DNA-associated proteins by chromatin immunoprecipitation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKW626

A combined approach for the localization and tandem affinity purification of protein complexes from metazoans.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5062981

Production of large numbers of mitotic mammalian cells by use of the reversible microtubule inhibitor Nocodazole

26 November 2018

1 reference

12 December 2020

Identification and characterization of human cdc7 nuclear retention and export sequences in the context of chromatin binding

1 reference

12 December 2020

Mimosine arrests the cell cycle prior to the onset of DNA replication by preventing the binding of human Ctf4/And-1 to chromatin via Hif-1α activation in HeLa cells

1 reference

12 December 2020

Hsk1-Dfp1 is required for heterochromatin-mediated cohesion at centromeres

1 reference

12 December 2020

Physiological regulation of eukaryotic topoisomerase II

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKW626

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27407105%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27407105%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

PubMed publication ID

27407105

2 references