Origin of the genetic code: a testable hypothesis based on tRNA structure, sequence, and kinetic proofreading (Q28776301)

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18 February 2023

1

J J Hopfield

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author name string

J. J. Hopfield

series ordinal

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A279919

full work available at URL

18 February 2023

language of work or name

English

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publication date

September 1978

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https://europepmc.org/articles/PMC336109

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A279919

https://europepmc.org/articles/PMC336109?pdf=render

18 February 2023

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A279919

https://pnas.org/doi/pdf/10.1073/pnas.75.9.4334

18 February 2023

1 reference

Crossref

DOI

10.1073/PNAS.75.9.4334

https://api.crossref.org/works/10.1073/PNAS.75.9.4334

Proceedings of the National Academy of Sciences of the United States of America

18 February 2023

published in

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volume

75

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page(s)

4334-8

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issue

9

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cites work

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Kinetic Proofreading: A New Mechanism for Reducing Errors in Biosynthetic Processes Requiring High Specificity

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The origin of the genetic code

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Evolution of the genetic apparatus

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The fundamental nature of the genetic code: prebiotic interactions between polynucleotides and polyamino acids or their derivatives

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The molecular basis for the genetic code

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Rearrangement of the secondary structure of the secondary structure of tryptophan sRNA in Escherichia coli

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The General Structure of Transfer RNA Molecules

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Structure of yeast phenylalanine tRNA at 3 Å resolution

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The mechanism of aminoacylation of transfer RNA.

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A speculation on the origin of protein synthesis

3 June 2018

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A cybernetic approach to the origin of the genetic coding mechanism. I. Methodological principles

3 June 2018

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Cell-free systems of polypeptide biosynthesis and approaches to the evolution of translation apparatus

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Codon-dependent rearrangement of the three-dimensional structure of phenylalanine tRNA, exposing the T-psi-C-G sequence for binding to the 50S ribosomal subunit

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The rates of evolution in some ribosomal components

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Is there a physical chemical basis for the present genetic code?

3 June 2018

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12 December 2020

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Molecular Mechanics of Translation : a Reciprocating Ratchet Mechanism

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The modification of nucleosides and nucleotides. X. Evidence for the important role of inosine residue in codon recognition of yeast alanine tRNA

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The Kinetics of Renaturation of 5-S RNA from Escherichia coli in the Presence of Mg2+ Ions

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Possibilities for the evolution of the genetic code from a preceding form

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Experimental investigation on the origin of the genetic code

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Models for the evolution of codon assignments

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Template-directed synthesis with adenosine-5'-phosphorimidazolide

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A speculation on the origin of the genetic code

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Triplet Nucleotide–Amino-acid Pairing; a Stereo-chemical Basis for the Division between Protein and Non-protein Amino-acids

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Stereochemical Relationship Between Coding Triplets and Amino-Acids

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