KLF6 induces apoptosis in prostate cancer cells through up-regulation of ATF3 (Q28771723)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

1 reference

Xiangwei Huang

1

1 reference

14 February 2017

Xia Li

series ordinal

2

1 reference

14 February 2017

Bin Guo

series ordinal

3

1 reference

14 February 2017

language of work or name

English

0 references

publication date

31 October 2008

1 reference

14 February 2017

1 reference

14 February 2017

283

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14 February 2017

29795–29801

1 reference

14 February 2017

44

1 reference

14 February 2017

Stress response gene ATF3 is a target of c-myc in serum-induced cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Identification of ATF-3, caveolin-1, DLC-1, and NM23-H2 as putative antitumorigenic, progesterone-regulated genes for ovarian cancer cells by gene profiling

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Gene expression profiling predicts clinical outcome of prostate cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Deletion, mutation, and loss of expression of KLF6 in human prostate cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

KLF6, a candidate tumor suppressor gene mutated in prostate cancer

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

PUMA induces the rapid apoptosis of colorectal cancer cells

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Analysis of ATF3, a transcription factor induced by physiological stresses and modulated by gadd153/Chop10

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

The tumor metastasis suppressor gene Drg-1 down-regulates the expression of activating transcription factor 3 in prostate cancer.

16 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Hypoxia: targeting the tumour

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

The expression of transcription factor activating transcription factor 3 in the human prostate and its regulation by androgen in prostate cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Regulation of Kruppel-like factor 6 tumor suppressor activity by acetylation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Tumor hypoxia: causative factors, compensatory mechanisms, and cellular response

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Frequent inactivation of the tumor suppressor Kruppel-like factor 6 (KLF6) in hepatocellular carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Role for activating transcription factor 3 in stress-induced beta-cell apoptosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Krüppel-like factor 6 is frequently down-regulated and induces apoptosis in non-small cell lung cancer cells.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

The molecular biology and nomenclature of the activating transcription factor/cAMP responsive element binding family of transcription factors: activating transcription factor proteins and homeostasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

The roles of ATF3 in glucose homeostasis. A transgenic mouse model with liver dysfunction and defects in endocrine pancreas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Dual regulation of proliferation and apoptosis: c-myc in bitransgenic murine mammary tumor models

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

ATF3 and stress responses.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

ATF3 gene. Genomic organization, promoter, and regulation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2573052

Cyclin-dependent kinase inhibition by the KLF6 tumor suppressor protein through interaction with cyclin D1.

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

Involvement of transcriptional repressor ATF3 in acceleration of caspase protease activation during DNA damaging agent-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

A potential dichotomous role of ATF3, an adaptive-response gene, in cancer development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

Kruppel-like factor 6 (KLF6) affects the promoter activity of the alpha1-proteinase inhibitor gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

A Germline DNA Polymorphism Enhances Alternative Splicing of theKLF6Tumor Suppressor Gene and Is Associated with Increased Prostate Cancer Risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M802515200

In vivo regulation of p21 by the Kruppel-like factor 6 tumor-suppressor gene in mouse liver and human hepatocellular carcinoma

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18755691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Allelic loss on chromosome 10 in prostate adenocarcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18755691

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18755691