A reappraisal of the mechanism by which plant sterols promote neutral sterol loss in mice (Q28743016)

1

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Folkert Kuipers

2

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Yuguang Lin

3

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Elke A Trautwein

Creative Commons Attribution 4.0 International

4

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language of work or name

English

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publication date

2011

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published in

PLOS One

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volume

6

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issue

6

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page(s)

e21576

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copyright license

start time

30 June 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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ABCG5 and ABCG8 require MDR2 for secretion of cholesterol into bile

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A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

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Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol

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Hepatobiliary cholesterol transport is not impaired in Abca1-null mice lacking HDL

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Biliary sterol secretion is not required for macrophage reverse cholesterol transport

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Transintestinal cholesterol efflux

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Peroxisome proliferator-activated receptor delta activation leads to increased transintestinal cholesterol efflux

20 June 2018

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Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol

20 June 2018

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ABCA1 plays no role in the centripetal movement of cholesterol from peripheral tissues to the liver and intestine in the mouse

20 June 2018

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Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

20 June 2018

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Targeted depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss

20 June 2018

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Compared with Acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol

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Disruption of Abcg5 and Abcg8 in mice reveals their crucial role in biliary cholesterol secretion

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Induction of intestinal ATP-binding cassette transporters by a phytosterol-derived liver X receptor agonist

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Increased intestinal ABCA1 expression contributes to the decrease in cholesterol absorption after plant stanol consumption

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Plant sterols and stanols: effects on mixed micellar composition and LXR (target gene) activation

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Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

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Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.

21 January 2018

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Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe

21 January 2018

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ATP-binding cassette transporter A1 (ABCA1) affects total body sterol metabolism.

21 January 2018

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Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.

21 January 2018

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Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

21 January 2018

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Regulation of direct transintestinal cholesterol excretion in mice

21 January 2018

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Differential intestinal mucosal protein expression in hypercholesterolemic mice fed a phytosterol-enriched diet

21 January 2018

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Plant stanols dose-dependently decrease LDL-cholesterol concentrations, but not cholesterol-standardized fat-soluble antioxidant concentrations, at intakes up to 9 g/d

21 January 2018

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12 December 2020

Origins of neutral sterols in human feces studied by stable isotope labeling (D and 13C). Existence of an external secretion of cholesterol

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12 December 2020

Effect of micellar beta-sitosterol on cholesterol metabolism in CaCo-2 cells

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12 December 2020

Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter

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12 December 2020

Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice

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12 December 2020

10.1371/JOURNAL.PONE.0021576

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