Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae (Q28652128)

Stephanie L Begg

1

0 references

Rafael Couñago

Rafael M Couñago

4

0 references

Bart Eijkelkamp

Bart A Eijkelkamp

2

0 references

Cheryl-lynn Y Ong

Cheryl-Lynn Y Ong

7

0 references

Megan J Maher

Megan J Maher

6

0 references

Christopher A McDevitt

Christopher A McDevitt

12

0 references

Megan L O'Mara

Megan L O'Mara

10

0 references

Alastair G McEwan

Alastair G McEwan

8

0 references

author name string

Zhenyao Luo

3

0 references

Jacqueline R Morey

5

0 references

James C Paton

Creative Commons Attribution 4.0 International

11

0 references

language of work or name

English

0 references

publication date

3 March 2015

0 references

published in

Nature Communications

0 references

volume

6

0 references

page(s)

6418

0 references

copyright license

start time

3 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

A new structural paradigm in copper resistance in Streptococcus pneumoniae

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

A Molecular Mechanism for Bacterial Susceptibility to Zinc

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Features and development of Coot

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Mechanisms of cadmium carcinogenesis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

AdcAII, a new pneumococcal Zn-binding protein homologous with ABC transporters: biochemical and structural analysis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Structure and metal exchange in the cadmium carbonic anhydrase of marine diatoms

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Iterative model building, structure refinement and density modification with the PHENIX AutoBuild wizard

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Inference of macromolecular assemblies from crystalline state

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Solving structures of protein complexes by molecular replacement with Phaser

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

UCSF Chimera--a visualization system for exploratory research and analysis

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

The crystal structure of pneumococcal surface antigen PsaA reveals a metal-binding site and a novel structure for a putative ABC-type binding protein

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

The novel transcriptional regulator SczA mediates protection against Zn2+ stress by activation of the Zn2+-resistance gene czcD in Streptococcus pneumoniae

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Extracellular zinc competitively inhibits manganese uptake and compromises oxidative stress management in Streptococcus pneumoniae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Physical characterization of the manganese-sensing pneumococcal surface antigen repressor from Streptococcus pneumoniae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Analysis of mutants disrupted in bacillithiol metabolism in Staphylococcus aureus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

In situ determination of manganese(II) speciation in Deinococcus radiodurans by high magnetic field EPR: detection of high levels of Mn(II) bound to proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Streptococcus pneumoniae uses glutathione to defend against oxidative stress and metal ion toxicity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Metal site occupancy and allosteric switching in bacterial metal sensor proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

The metalloregulatory zinc site in Streptococcus pneumoniae AdcR, a zinc-activated MarR family repressor

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Central role of manganese in regulation of stress responses, physiology, and metabolism in Streptococcus pneumoniae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

WIWS: a protein structure bioinformatics Web service collection

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Cadmium stress: an oxidative challenge.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Role of the manganese efflux system mntE for signalling and pathogenesis in Streptococcus pneumoniae

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Glutathione and transition-metal homeostasis in Escherichia coli

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Biochemistry: a cadmium enzyme from a marine diatom

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Molecular analysis of the psa permease complex of Streptococcus pneumoniae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Virulence of Streptococcus pneumoniae: PsaA mutants are hypersensitive to oxidative stress

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Role of manganese-containing superoxide dismutase in oxidative stress and virulence of Streptococcus pneumoniae.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

CzcD is a heavy metal ion transporter involved in regulation of heavy metal resistance in Ralstonia sp. strain CH34

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Cloning and expression of cadD, a new cadmium resistance gene of Staphylococcus aureus.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

The adc locus, which affects competence for genetic transformation in Streptococcus pneumoniae, encodes an ABC transporter with a putative lipoprotein homologous to a family of streptococcal adhesins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Competence and virulence of Streptococcus pneumoniae: Adc and PsaA mutants exhibit a requirement for Zn and Mn resulting from inactivation of putative ABC metal permeases

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Manganese acquisition by Lactobacillus plantarum.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Quantitative assessment of worldwide contamination of air, water and soils by trace metals

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

Ultrasensitivity and heavy-metal selectivity of the allosterically modulated MerR transcription complex

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4366526

637. The stability of transition-metal complexes

3 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Structure of Escherichia coli aminopeptidase P in complex with the inhibitor apstatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Putative copper- and zinc-binding motifs in Streptococcus pneumoniae identified by immobilized metal affinity chromatography and mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Metal ions in biological catalysis: from enzyme databases to general principles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Role of cysteinyl residues in sensing Pb(II), Cd(II), and Zn(II) by the plasmid pI258 CadC repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Bacillithiol is a major buffer of the labile zinc pool in Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Cadmium and cobalt substitution for zinc in a marine diatom

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

Effect of the cyanide-producing bacterium Chromobacterium violaceum on ultraflat Au surfaces

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

An Antimicrobial Role for Zinc in Innate Immune Defense Against Group A Streptococcus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7418

A PerR-regulated metal transporter (PmtA) is an interface between oxidative stress and metal homeostasis in Streptococcus pyogenes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25731976

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glutathione: a key component of the cytoplasmic labile iron pool

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25731976