S-adenosylmethionine synthesis: molecular mechanisms and clinical implications (Q28646532)

1

1 reference

3 February 2017

L. Alvarez

2

1 reference

3 February 2017

P. Ortiz

3

1 reference

3 February 2017

M. A. Pajares

Pharmacology & Therapeutics

4

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3 February 2017

1 January 1997

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3 February 2017

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3 February 2017

73

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3 February 2017

3

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3 February 2017

265–280

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3 February 2017

Analysis of the 5' non-coding region of rat liver S-adenosylmethionine synthetase mRNA and comparison of the Mr deduced from the cDNA sequence and the purified enzyme

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Characterization of a full-length cDNA encoding human liver S-adenosylmethionine synthetase: tissue-specific gene expression and mRNA levels in hepatopathies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Expression of rat liver S-adenosylmethionine synthetase in Escherichia coli results in two active oligomeric forms

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effects of prolonged ethanol feeding on methionine metabolism in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosylmethionine prevents total parenteral nutrition-induced cholestasis in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Biochemical studies on the enzymatic deficiencies in hereditary tyrosinemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Distinct phenotypes generated by overexpression and suppression of S-adenosyl-L-methionine synthetase reveal developmental patterns of gene silencing in tobacco

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosylmethionine protects against acetaminophen hepatotoxicity in two mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Systemic glutathione deficiency in symptom-free HIV-seropositive individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Conversion of rat liver S-adenosyl-L-methionine synthetase from high-Mr form to low-Mr form by LiBr

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Purification and comparison of two forms of S-adenosyl-L-methionine synthetase from rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Specific loss of the high-molecular-weight form of S-adenosyl-L-methionine synthetase in human liver cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Biological Methylation: Selected Aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Cerebrospinal fluid S-adenosylmethionine (SAMe) and glutathione concentrations in HIV infection Effect of parenteral treatment with SAMe

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Transsulfuration in mammals: fetal and early development of methionine-activating enzyme and its relation to hormonal influences

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Abnormal metabolism of S-adenosyl-L-methionine in hypoxic rat liver. Similarities to its abnormal metabolism in alcoholic cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Hyperhomocysteinemia: an independent risk factor for vascular disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Methionine transamination in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Inactivation and dissociation of S-adenosylmethionine synthetase by modification of sulfhydryl groups and its possible occurrence in cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosylmethionine treatment prevents carbon tetrachloride-induced S-adenosylmethionine synthetase inactivation and attenuates liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Study of the rat liver S-adenosylmethionine synthetase active site with 8-azido ATP.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Chromosomal localization and catalytic properties of the recombinant alpha subunit of human lymphocyte methionine adenosyltransferase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Transcription factor interactions: selectors of positive or negative regulation from a single DNA element.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Glutathione in Parkinson's disease: a link between oxidative stress and mitochondrial damage?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Decreased blood levels of ethanol and acetaldehyde by S-adenosyl-L-methionine in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosyl-L-methionine protection against alpha-naphthylisothiocyanate-induced cholestasis in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Evidence that S-adenosylmethionine and N-acetylcysteine reduce injury from sequential cold and warm ischemia in the isolated perfused rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Low concentrations of acid-soluble thiol (cysteine) in the blood plasma of HIV-1-infected patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effect of the variations of S-adenosyl-L-methionine liver content on fat accumulation and ethanol metabolism in ethanol-intoxicated rats

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Methionine metabolism in mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Inactivation of betaine-homocysteine methyltransferase by adenosylmethionine and adenosylethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Activation of cystathionine synthase by adenosylmethionine and adenosylethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Abnormal methionine adenosyltransferase in hypermethioninemia

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The Minimal Gene Complement of Mycoplasma genitalium

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Methionine adenosyltransferase deficiency: new enzymatic defect associated with hypermethioninemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Hypermethioninemia associated with methionine adenosyltransferase deficiency: Clinical, morphologic, and biochemical observations on four patients

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Glucocorticoid Regulation of Hepatic S-Adenosylmethionine Synthetase Gene Expression

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Reciprocal gamma-glutamyl transferase and cystathionase activity in guinea pig, rat and human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Fractionation of methionine adenosyltransferase isozymes (rat liver)

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Isolation of a cDNA encoding the rat liver S-adenosylmethionine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Immunohistochemical analysis of rat S-adenosylmethionine synthetase isozymes in developmental liver.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Evidence of brain methyltransferase inhibition and early brain involvement in HIV-positive patients

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Rate of Disappearance From Plasma of Intravenously Administered Methionine in Patients With Liver Damage

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Methionine adenosyltransferase: structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Antigenic conservation of primary structural regions of S-adenosylmethionine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Separation of rat liver methionine adenosyltransferase isozymes by hydrophobic chromatography

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Feedback inhibition of methylene-tetrahydrofolate reductase in rat liver by S-adenosylmethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Mammalian methylenetetrahydrofolate reductase. Partial purification, properties, and inhibition by S-adenosylmethionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

In vivo spin-trapping of trichloromethyl radicals formed from CCl4

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

EFFECTS OF PROLONGED ETHANOL INTAKE: PRODUCTION OF FATTY LIVER DESPITE ADEQUATE DIETS.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosyl-L-methionine attenuates alcohol-induced liver injury in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Hepatic Phosphatidylethanolamine Methyltransferase Activity Is Decreased by Ethanol and Increased by Phosphatidylcholine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Phosphatidylcholine protects against fibrosis and cirrhosis in the baboon

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

COUP-TF acts as a competitive repressor for estrogen receptor-mediated activation of the mouse lactoferrin gene

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Regulatory properties of adenosine triphosphate-l-methionine S-adenosyltransferase of rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Defective methionine metabolism in cirrhosis: relation to severity of liver disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosyl-L-methionine synthetase and phospholipid methyltransferase are inhibited in human cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

What is the function of phospholipid N-methylation?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The alpha-form of S-adenosylmethionine synthetase isozymes from liver is principally functional

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

1 reference

7 January 2021

Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Folate-deficiency-induced homocysteinaemia in rats: disruption of S-adenosylmethionine's co-ordinate regulation of homocysteine metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Site-directed mutagenesis of rat liver S-adenosylmethionine synthetase. Identification of a cysteine residue critical for the oligomeric state

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Labile methyl balances for normal humans on various dietary regimens

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Labile methyl group balances in the human: The role of sarcosine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Labile methyl groups and the promotion of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Multiple species of mammalian S-adenosylmethionine synthetase. Partial purification and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effect of S-adenosyl-L-methionine on thioacetamide-induced liver damage in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The role of cysteine-150 in the structure and activity of rat liver S-adenosyl-L-methionine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

How is rat liver S-adenosylmethionine synthetase regulated?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Protein kinase C phosphorylation of rat liver S-adenosylmethionine synthetase: dissociation and production of an active monomer

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effects of Diet and Other Factors on Methionine Adenosyltransferase Levels in Rat Liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

S-adenosyl-L-methionine a counter to lead intoxication?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Inhibition by ethanol of rat liver plasma membrane (Na+,K+)ATPase: protective effect of S-adenosyl-L-methionine, L-methionine, and N-acetylcysteine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Intracellular glutathione in human hepatocytes incubated with S-adenosyl-L-methionine and GSH-depleting drugs

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

DNA Methylation and Gene Function

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Increased sensitivity to oxidative injury in chinese hamster ovary cells stably transfected with rat liver S-adenosylmethionine synthetase cDNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Novel Escherichia coli K-12 mutants impaired in S-adenosylmethionine synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The fluidity of liver plasma membranes from patients with different types of liver injury

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Pathogenesis of subacute combined degeneration: a result of methyl group deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Association between Plasma Homocysteine Concentrations and Extracranial Carotid-Artery Stenosis

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Mechanisms of liver-specific gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Free-radical mechanisms in tissue injury

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Glutathione deficiency and human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Protective role of S-adenosyl-L-methionine on liver injury induced by D-galactosamine in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Protective role of S-adenosyl-l-methionine against acetaminophen induced mortality and hepatotoxicity in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Fractionation and kinetic properties of rat liver and kidney methionine adenosyltransferase isozymes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Synthesis of S-adenosylmethionine synthetase isozymes from rat and mouse livers. Immunochemical studies

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Central-nervous-system methyl-group metabolism in children with neurological complications of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Association of demyelination with deficiency of cerebrospinal-fluid S-adenosylmethionine in inborn errors of methyl-transfer pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Crystal structure of S-adenosylmethionine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The synthesis of the two S-adenosyl-methionine synthetases is differently regulated in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

SAM2 encodes the second methionine S-adenosyl transferase in Saccharomyces cerevisiae: physiology and regulation of both enzymes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effect of exogenous S-adenosyl-l-methionine on phosphatidylcholine synthesis by isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The effect of ethanol on one-carbon metabolism: Increased methionine catabolism and lipotrope methyl-group wastage

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

HNF1, a homeoprotein member of the hepatic transcription regulatory network

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Ethionine-induced changes in the activities of S-adenosylmethionine synthetase isozymes from rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Molecular mechanisms of an inborn error of methionine pathway. Methionine adenosyltransferase deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Effects of oral S-adenosyl-L-methionine on hepatic glutathione in patients with liver disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Impairment of bile secretion induced by exhaustive exercise in the rat. Protective effects of S-adenosyl-L-methionine

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Methylation deficiency causes vitamin B12-associated neuropathy in the pig.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Is methionine transaminated in skeletal muscle?

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

Gene regulation in rodent hepatocytes during development, differentiation and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

The protective effect of tinoridine against carbon tetrachloride hepatotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0163-7258%2896%2900197-0

7 January 2021

10.1016/S0163-7258(96)00197-0

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1066549

1066549

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference