Vav2 is an activator of Cdc42, Rac1, and RhoA (Q28610652)

2

1 reference

3 February 2017

B. Liu

3

1 reference

3 February 2017

K. D. Ritola

4

1 reference

3 February 2017

D. Chiang

5

1 reference

3 February 2017

S. L. Campbell

6

1 reference

3 February 2017

K. Burridge

7

1 reference

3 February 2017

C. J. Der

Journal of Biological Chemistry

8

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3 February 2017

language of work or name

English

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publication date

7 April 2000

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3 February 2017

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3 February 2017

275

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3 February 2017

14

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3 February 2017

10141–10149

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3 February 2017

The Dbl family of oncogenes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Rho effectors and reorganization of actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Rho family proteins and Ras transformation: the RHOad less traveled gets congested.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Selective activation of the JNK signaling cascade and c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of the JNK/SAPK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Activation of the nuclear factor-kappaB by Rho, CDC42, and Rac-1 proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Transforming potential of Dbl family proteins correlates with transcription from the cyclin D1 promoter but not with activation of Jun NH2-terminal kinase, p38/Mpk2, serum response factor, or c-Jun

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Expression cloning of lsc, a novel oncogene with structural similarities to the Dbl family of guanine nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

The faciogenital dysplasia gene product FGD1 functions as a Cdc42Hs-specific guanine-nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Lck regulates Vav activation of members of the Rho family of GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Faciogenital dysplasia protein (FGD1) and Vav, two related proteins required for normal embryonic development, are upstream regulators of Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Phosphorylation-dependent and constitutive activation of Rho proteins by wild-type and oncogenic Vav-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Expression cloning of lfc, a novel oncogene with structural similarities to guanine nucleotide exchange factors and to the regulatory region of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

CDC42 and FGD1 cause distinct signaling and transforming activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Identification of VAV2 on 9q34 and its exclusion as the tuberous sclerosis gene TSC1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Loss of the amino-terminal helix-loop-helix domain of the vav proto-oncogene activates its transforming potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Involvement of NH(2)-terminal sequences in the negative regulation of Vav signaling and transforming activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Association between GTPase activators for Rho and Ras families.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Biological assays for Ras transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Transcriptional activation analysis of oncogene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Ras-mediated transcription activation: analysis by transient cotransfection assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

JNK is involved in signal integration during costimulation of T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Purification of recombinant Rho/Rac/G25K from Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Investigation of the GTP-binding/GTPase cycle of Cdc42Hs using fluorescence spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Molecular cloning of cDNAs encoding the GAP-associated protein p190: implications for a signaling pathway from ras to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

Matrix-dependent Tiam1/Rac signaling in epithelial cells promotes either cell-cell adhesion or cell migration and is regulated by phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141

A novel regulator of p21-activated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.14.10141