A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity (Q28609427)

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English	A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity	scientific journal article

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scholarly article

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3 February 2017

A regulated interaction of syntaxin 1A with the antidepressant-sensitive norepinephrine transporter establishes catecholamine clearance capacity (English)

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3 February 2017

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12 May 2020

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Uhna Sung

1

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3 February 2017

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12 May 2020

Subramaniam Apparsundaram

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Aurelio Galli

3

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12 May 2020

Valentina Savchenko

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12 May 2020

Sally Schroeter

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12 May 2020

Kristopher M Kahlig

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12 May 2020

Michael W Quick

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12 May 2020

Randy D Blakely

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language of work or name

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publication date

1 March 2003

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3 February 2017

Journal of Neuroscience

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12 May 2020

23

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12 May 2020

1697-1709

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5

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3 February 2017

Europe PubMed Central

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12 May 2020

PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1.

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Multiple G protein-coupled receptors initiate protein kinase C redistribution of GABA transporters in hippocampal neurons.

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter.

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Interaction of syntaxins with the amiloride-sensitive epithelial sodium channel

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https://pubmed.ncbi.nlm.nih.gov/12629174

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Phosphorylation and sequestration of serotonin transporters differentially modulated by psychostimulants

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Localization of the noradrenaline transporter in rat adrenal medulla and PC12 cells: evidence for its association with secretory granules in PC12 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Syntaxin 1 interacts with the L(D) subtype of voltage-gated Ca(2+) channels in pancreatic beta cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Role of norepinephrine in depression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Noradrenergic approaches to antidepressant therapy.

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Neurotoxins affecting neuroexocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Immunolocalization of the cocaine- and antidepressant-sensitive l-norepinephrine transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Mice lacking the norepinephrine transporter are supersensitive to psychostimulants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Biogenic amine transporters: regulation in flux

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Membrane fusion and exocytosis

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https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Close is not enough: SNARE-dependent membrane fusion requires an active mechanism that transduces force to membrane anchors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Mutation of arginine 44 of GAT-1, a (Na(+) + Cl(-))-coupled gamma-aminobutyric acid transporter from rat brain, impairs net flux but not exchange

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Transport rates of GABA transporters: regulation by the N-terminal domain and syntaxin 1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Cocaine and antidepressant-sensitive biogenic amine transporters exist in regulated complexes with protein phosphatase 2A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Ultrastructural localization of the serotonin transporter in superficial and deep layers of the rat prelimbic prefrontal cortex and its spatial relationship to dopamine terminals

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Direct interaction of a brain voltage-gated K+ channel with syntaxin 1A: functional impact on channel gating.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Calcium- and syntaxin 1-mediated trafficking of the neuronal glycine transporter GLYT2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Modulation of prefrontal cortical-striatal circuits: relevance to therapeutic treatments for Tourette syndrome and attention-deficit hyperactivity disorder.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Trafficking-dependent and -independent pathways of neurotransmitter transporter regulation differentially involving p38 mitogen-activated protein kinase revealed in studies of insulin modulation of norepinephrine transport in SK-N-SH cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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PICKing on transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Regulation of the serotonin transporter by interacting proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Chronic and acute regulation of Na+/Cl- -dependent neurotransmitter transporters: drugs, substrates, presynaptic receptors, and signaling systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Serotonin transporter function and pharmacology are sensitive to expression level: evidence for an endogenous regulatory factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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The 25-kDa synaptosome-associated protein (SNAP-25) binds and inhibits delayed rectifier potassium channels in secretory cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determinants within the C-terminus of the human norepinephrine transporter dictate transporter trafficking, stability, and activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Binding and transport in norepinephrine transporters. Real-time, spatially resolved analysis in single cells using a fluorescent substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Effect of psychotropic drugs on the uptake of H3-norepinephrine by tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Myocardial beta-adrenergic desensitization and neuronal norepinephrine uptake function in idiopathic dilated cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Effect of drugs on the uptake and metabolism of H3-norepinephrine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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INHIBITION OF NORADRENALINE UPTAKE BY DRUGS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Cocaine inhibition of ligand binding at dopamine, norepinephrine and serotonin transporters: a structure-activity study

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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inferred from PubMed ID database lookup

Decreased adrenergic neuronal uptake activity in experimental right heart failure. A chamber-specific contributor to beta-adrenoceptor downregulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Role of transmitter uptake mechanisms in synaptic neurotransmission

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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The Uptake, Storage, Release and Metabolism of Noradrenaline in Sympathetic Nerves

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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The catecholamine hypothesis of affective disorders: a review of supporting evidence

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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Nucleus locus ceruleus: new evidence of anatomical and physiological specificity

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

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High-affinity [3H]desipramine binding in the peripheral and central nervous system: a specific site associated with the neuronal uptake of noradrenaline.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Norepinephrine kinetics in essential hypertension. Defective neuronal uptake of norepinephrine in some patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Sodium-dependent norepinephrine-induced currents in norepinephrine-transporter-transfected HEK-293 cells blocked by cocaine and antidepressants

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Manic-depression and the norepinephrine transporter gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Cellular and subcellular localization of syntaxin-like immunoreactivity in the rat striatum and cortex

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The syntaxin family of vesicular transport receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for reduction of norepinephrine uptake sites in the failing human heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of locally applied cocaine, lidocaine, and various uptake blockers on monoamine transmission in the ventral tegmental area of freely moving rats: a microdialysis study on monoamine interrelationships.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

n-Sec1: a neural-specific syntaxin-binding protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional impact of syntaxin on gating of N-type and Q-type calcium channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that syntaxin 1A is involved in storage in the secretory pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoform-specific interaction of the alpha1A subunits of brain Ca2+ channels with the presynaptic proteins syntaxin and SNAP-25

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inability to N-glycosylate the human norepinephrine transporter reduces protein stability, surface trafficking, and transport activity but not ligand recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion binding and permeation at the GABA transporter GAT1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C activation regulates human serotonin transporters in HEK-293 cells via altered cell surface expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a CNS cell line, CAD, in which morphological differentiation is initiated by serum deprivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Varicosities of single sympathetic nerve terminals possess syntaxin zones and different synaptotagmin N-terminus labelling following stimulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced levels of norepinephrine transporters in the locus coeruleus in major depression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological profile of antidepressants and related compounds at human monoamine transporters

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Munc13-1 is a presynaptic phorbol ester receptor that enhances neurotransmitter release

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein kinase C regulates the interaction between a GABA transporter and syntaxin 1A

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patch-clamp and amperometric recordings from norepinephrine transporters: channel activity and voltage-dependent uptake

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute regulation of norepinephrine transport: I. protein kinase C-linked muscarinic receptors influence transport capacity and transporter density in SK-N-SH cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute regulation of norepinephrine transport: II. PKC-modulated surface expression of human norepinephrine transporter proteins.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antidepressant efficacy and tolerability of the selective norepinephrine reuptake inhibitor reboxetine: a review.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12629174

12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.23-05-01697.2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741950&resulttype=core&format=json

12 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741950&resulttype=core&format=json

12 May 2020

2 references

3 February 2017

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6741950&resulttype=core&format=json

12 May 2020

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