The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways (Q28594395)

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English	The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways	scientific journal article

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scholarly article

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31 January 2017

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways (English)

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31 January 2017

toll-like receptor

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Mitogen-activated protein kinase-activated protein kinase 3

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GOA release 2020-03-11

MAP kinase-activated protein kinase 2

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GOA release 2020-03-11

Ribosomal protein S6 kinase polypeptide 3

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GOA release 2020-03-11

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based on heuristic

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Matthias Gaestel

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object named as

Matthias Gaestel

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object named as

Rossana Zaru

1

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object named as

Colin Watts

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Natalia Ronkina

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object named as

Natalia Ronkina

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31 January 2017

author name string

J. Simon C. Arthur

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31 January 2017

language of work or name

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publication date

1 November 2007

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31 January 2017

Nature Immunology

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31 January 2017

8

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31 January 2017

1227–1235

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31 January 2017

11

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31 January 2017

Evidence for two catalytically active kinase domains in pp90rsk

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https://api.crossref.org/works/10.1038%2FNI1517

21 January 2018

Antigen presentation and T cell stimulation by dendritic cells

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7 January 2021

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Dendritic cells in a mature age.

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7 January 2021

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Cell biology of antigen processing in vitro and in vivo

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7 January 2021

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Mobilization of MHC class I molecules from late endosomes to the cell surface following activation of CD34-derived human Langerhans cells.

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7 January 2021

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Dendritic cell maturation triggers retrograde MHC class II transport from lysosomes to the plasma membrane.

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7 January 2021

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Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

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7 January 2021

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Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination

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7 January 2021

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Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination

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7 January 2021

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Regulation of phagosome maturation by signals from toll-like receptors.

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Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

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7 January 2021

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Transient aggregation of ubiquitinated proteins during dendritic cell maturation

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7 January 2021

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How Toll-like receptors signal: what we know and what we don't know

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7 January 2021

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RSK and MSK in MAP kinase signalling

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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MAPKAP kinases - MKs - two's company, three's a crowd

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7 January 2021

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ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions

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7 January 2021

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Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

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7 January 2021

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A phosphoserine-regulated docking site in the protein kinase RSK2 that recruits and activates PDK1.

1 reference

https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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Functional characterization of human RSK4, a new 90-kDa ribosomal S6 kinase, reveals constitutive activation in most cell types.

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

based on heuristic

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MSK1 activity is controlled by multiple phosphorylation sites.

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

1 reference

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7 January 2021

based on heuristic

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MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels

1 reference

https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

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7 January 2021

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MSK2 and MSK1 mediate the mitogen- and stress-induced phosphorylation of histone H3 and HMG-14

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase

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7 January 2021

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Mnk2 and Mnk1 are essential for constitutive and inducible phosphorylation of eukaryotic initiation factor 4E but not for cell growth or development

1 reference

https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo.

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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The mitogen-activated protein kinase (MAPK)-activated protein kinases MK2 and MK3 cooperate in stimulation of tumor necrosis factor biosynthesis and stabilization of p38 MAPK.

1 reference

https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

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https://api.crossref.org/works/10.1038%2FNI1517

7 January 2021

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90-kDa ribosomal S6 kinase is phosphorylated and activated by 3-phosphoinositide-dependent protein kinase-1.

1 reference

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7 January 2021

based on heuristic

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Altered extracellular signal-regulated kinase signaling and glycogen metabolism in skeletal muscle from p90 ribosomal S6 kinase 2 knockout mice

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7 January 2021

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Structural bioinformatics-based design of selective, irreversible kinase inhibitors

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7 January 2021

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BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo

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7 January 2021

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Attenuation of proteasome-induced proteolysis in skeletal muscle by {beta}-hydroxy-{beta}-methylbutyrate in cancer-induced muscle loss

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7 January 2021

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Identification of serine 380 as the major site of autophosphorylation of Xenopus pp90rsk

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7 January 2021

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p38 map kinase substrate specificity differs greatly for protein and peptide substrates

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7 January 2021

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Distinct cellular functions of MK2.

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7 January 2021

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The protein kinase complement of the human genome

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Mechanism of activation of protein kinase B by insulin and IGF-1

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p38 Kinase-dependent MAPKAPK-2 activation functions as 3-phosphoinositide-dependent kinase-2 for Akt in human neutrophils

1 reference

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7 January 2021

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Hsp27 regulates Akt activation and polymorphonuclear leukocyte apoptosis by scaffolding MK2 to Akt signal complex

1 reference

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7 January 2021

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A clickable inhibitor reveals context-dependent autoactivation of p90 RSK

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7 January 2021

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Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses.

1 reference

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7 January 2021

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EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

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The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1

1 reference

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7 January 2021

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p90(RSK) is a serum-stimulated Na+/H+ exchanger isoform-1 kinase. Regulatory phosphorylation of serine 703 of Na+/H+ exchanger isoform-1

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7 January 2021

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Distinct endocytotic pathways in epidermal growth factor-stimulated human carcinoma A431 cells

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Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products

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Ribosomal S6 kinase (RSK) regulates phosphorylation of filamin A on an important regulatory site

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7 January 2021

based on heuristic

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MSK1 and MSK2 are required for the mitogen- and stress-induced phosphorylation of CREB and ATF1 in fibroblasts

1 reference

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7 January 2021

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Differential regulation of T-cell growth by IL-2 and IL-15

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[29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf

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7 January 2021

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31 January 2017

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31 January 2017

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