Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48 (Q28594252)

Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1

GOA release 2020-03-11

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GOA release 2020-03-11

author name string

K. Hirano

1

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31 January 2017

S. G. Young

2

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31 January 2017

R. V. Farese

3

1 reference

31 January 2017

J. Ng

4

1 reference

31 January 2017

E. Sande

5

1 reference

31 January 2017

C. Warburton

6

1 reference

31 January 2017

L. M. Powell-Braxton

7

1 reference

31 January 2017

N. O. Davidson

Journal of Biological Chemistry

8

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31 January 2017

language of work or name

English

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publication date

26 April 1996

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31 January 2017

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31 January 2017

271

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31 January 2017

9887–9890

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31 January 2017

17

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31 January 2017

Recent progress in understanding apolipoprotein B.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Apolipoprotein B messenger RNA editing is developmentally regulated in pig small intestine: nucleotide comparison of apolipoprotein B editing regions in five species

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Mutagenesis of the human apolipoprotein B gene in a yeast artificial chromosome reveals the site of attachment for apolipoprotein(a)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Site-specific mutagenesis demonstrates that cysteine 4326 of apolipoprotein B is required for covalent linkage with apolipoprotein (a) in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Molecular cloning of an apolipoprotein B messenger RNA editing protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Alternative mRNA splicing and differential promoter utilization determine tissue-specific expression of the apolipoprotein B mRNA-editing protein (Apobec1) gene in mice. Structure and evolution of Apobec1 and related nucleoside/nucleotide deaminases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Apolipoprotein B mRNA editing is associated with UV crosslinking of proteins to the editing site

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887

Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.271.17.9887