An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo (Q28593933)

31 January 2017

title

An intrinsic mechanism predisposes Foxp3-expressing regulatory T cells to Th2 conversion in vivo (English)

1 reference

31 January 2017

1 reference

GOA release 2020-03-11

3

Richard A. Flavell

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31 January 2017

Yunqi Wang

1

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31 January 2017

Abdallah Souabni

series ordinal

2

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31 January 2017

Yisong Y. Wan

series ordinal

4

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31 January 2017

language of work or name

English

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publication date

15 November 2010

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31 January 2017

published in

Journal of Immunology

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31 January 2017

volume

185

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31 January 2017

issue

10

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31 January 2017

page(s)

5983–5992

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The transcription factors T-bet and GATA-3 control alternative pathways of T-cell differentiation through a shared set of target genes

31 January 2017

cites work

1 reference

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Control of regulatory T cell development by the transcription factor Foxp3

17 March 2017

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17 March 2017

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17 March 2017

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17 March 2017

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7 April 2017

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7 April 2017

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The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

7 April 2017

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Runx-CBFbeta complexes control expression of the transcription factor Foxp3 in regulatory T cells

29 September 2017

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Instability of the transcription factor Foxp3 leads to the generation of pathogenic memory T cells in vivo

29 September 2017

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29 September 2017

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29 September 2017

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STAT6 Inhibits TGF-beta1-mediated Foxp3 induction through direct binding to the Foxp3 promoter, which is reverted by retinoic acid receptor

29 September 2017

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GATA3-driven Th2 responses inhibit TGF-beta1-induced FOXP3 expression and the formation of regulatory T cells.

29 September 2017

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Foxp3 in control of the regulatory T cell lineage

29 September 2017

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Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

29 September 2017

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Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease

29 September 2017

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Identifying Foxp3-expressing suppressor T cells with a bicistronic reporter

29 September 2017

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Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

29 September 2017

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29 September 2017

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Stat6-deficient mice develop airway hyperresponsiveness and peribronchial fibrosis during chronic fungal asthma.

29 September 2017

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29 September 2017

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Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells

29 September 2017

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Ectopic expression of activated Stat6 induces the expression of Th2-specific cytokines and transcription factors in developing Th1 cells

29 September 2017

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Stat6 is required for mediating responses to IL-4 and for development of Th2 cells.

3 June 2018

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Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells

20 June 2018

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Decreased FOXP3 protein expression in patients with asthma

27 November 2018

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Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches.

27 November 2018

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A LAT mutation that inhibits T cell development yet induces lymphoproliferation

27 November 2018

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A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.

27 November 2018

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Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter

27 November 2018

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Stat6-independent GATA-3 autoactivation directs IL-4-independent Th2 development and commitment.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974034

Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20944002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Foxp3-dependent programme of regulatory T-cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20944002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20944002

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.4049/JIMMUNOL.1001255

1 reference

31 January 2017

0 references

1 reference