16,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors (Q28580598)

31 January 2017

title

16,16-Dimethyl prostaglandin E2 inhibits indomethacin-induced small intestinal lesions through EP3 and EP4 receptors (English)

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regulation of small intestine smooth muscle contraction

31 January 2017

main subject

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small intestine smooth muscle contraction

GO:1904347

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positive regulation of small intestine smooth muscle contraction

GO:1990770

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negative regulation of small intestine smooth muscle contraction

GO:1904349

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negative regulation of nitric oxide metabolic process

GO:1904348

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positive regulation of nitric oxide metabolic process

GO:1904406

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16,16-dimethylprostaglandin E2

GO:1904407

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ChEBI release 2020-05-28

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Tomonori Kunikata

1

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31 January 2017

Akiko Tanaka

2

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31 January 2017

Tohru Miyazawa

3

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31 January 2017

Shinichi Kato

4

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31 January 2017

Koji Takeuchi

5

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31 January 2017

publication date

1 April 2002

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Digestive Diseases and Sciences

31 January 2017

published in

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31 January 2017

volume

47

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31 January 2017

issue

4

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31 January 2017

page(s)

894–904

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Alternative splicing of C-terminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity

31 January 2017

cites work

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Differential distribution of nitric oxide synthase between cell fractions isolated from the rat gastric mucosa

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Roles of enterobacteria, nitric oxide and neutrophil in pathogenesis of indomethacin-induced small intestinal lesions in rats

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Enteropooling assay: a test for diarrhea produced by prostaglandins

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The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach

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Prostaglandin E(2) stimulates rat and human colonic mucin exocytosis via the EP(4) receptor

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Resistance of germfree rats to indomethacin-induced intestinal lesions

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Correlation of quantitative changes of gastric mucosal glycoproteins with aspirin-induced gastric damage in rats

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Gastrointestinal ulcer formation in rabbits immunized with prostaglandin E2

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Prostanoid stimulation of anion secretion in guinea-pig gastric and ileal mucosa is mediated by different receptors

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Temporal relationship between cyclooxygenase inhibition, as measured by prostacyclin biosynthesis, and the gastrointestinal damage induced by indomethacin in the rat

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Nonsteroidal anti-inflammatory drug enteropathy in rats: role of permeability, bacteria, and enterohepatic circulation

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Nitric oxide, superoxide radicals and mast cells in pathogenesis of indomethacin-induced small intestinal lesions in rats

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Mechanisms of acute and chronic intestinal inflammation induced by indomethacin

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12 December 2020

Prostaglandin E inhibits indomethacin-induced gastric lesions through EP-1 receptors

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Roles of prostaglandin E-receptor subtypes in gastric and duodenal bicarbonate secretion in rats.

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Indometacin-induced gastrointestinal lesions in relation to tissue concentration, food intake and bacterial invasion in the rat

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Early histological features of small intestinal injury induced by indomethacin

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Presence of prostaglandin EP4 receptor gene expression in a rat gastric mucosal cell line

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Failure of parturition in mice lacking the prostaglandin F receptor

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Measurement of Cutaneous Inflammation: Estimation of Neutrophil Content with an Enzyme Marker

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A gastric housekeeping Cl- channel activated via prostaglandin EP3 receptor-mediated Ca2+/nitric oxide/cGMP pathway.

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Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo

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Effect of ecabet disodium, a novel locally-acting antiulcer drug, on epithelial restitution following injury by hypertonic NaCl in bullfrog stomach in vitro

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12 December 2020

Protective effect of lafutidine against indomethacin-induced intestinal ulceration in rats: relation to capsaicin-sensitive sensory neurons

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12 December 2020

Indomethacin-induced intestinal inflammation

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12 December 2020

Induction of nitric oxide synthase and microvascular injury in the rat jejunum provoked by indomethacin

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12 December 2020

Nonsteroidal antiinflammatory drug-induced intestinal inflammation in humans

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12 December 2020

Prostaglandin E(2)-activated housekeeping Cl(-) channels in the basolateral membrane of rat gastric parietal cells

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12 December 2020

Impaired duodenal bicarbonate secretion and mucosal integrity in mice lacking prostaglandin E-receptor subtype EP(3)

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12 December 2020

The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat.

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12 December 2020

Protection by aspirin of indomethacin-induced small intestinal damage in rats: mediation by salicylic acid

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12 December 2020

Impaired febrile response in mice lacking the prostaglandin E receptor subtype EP3

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12 December 2020

Vascular anatomy defines sites of indomethacin induced jejunal ulceration along the mesenteric margin

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12 December 2020