Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death (Q28579471)

2

1 reference

31 January 2017

Derek Timm

3

1 reference

31 January 2017

Kai Mao

4

1 reference

31 January 2017

Xianmin Xu

5

1 reference

31 January 2017

Qiangrong Liang

Journal of Biological Chemistry

6

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 January 2010

1 reference

31 January 2017

1 reference

31 January 2017

285

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31 January 2017

793–804

1 reference

31 January 2017

1

1 reference

31 January 2017

GATA-1 associates with and inhibits p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Diminished GATA4 protein levels contribute to hyperglycemia-induced cardiomyocyte injury

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Autophagy and signaling: their role in cell survival and cell death

17 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

17 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

LC3 conjugation system in mammalian autophagy

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Tissue-specific GATA factors are transcriptional effectors of the small GTPase RhoA

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The transcription factor GATA4 is activated by extracellular signal-regulated kinase 1- and 2-mediated phosphorylation of serine 105 in cardiomyocytes

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The role of autophagy during the early neonatal starvation period

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Autophagy: from phenomenology to molecular understanding in less than a decade

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

How to interpret LC3 immunoblotting

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Autophagy in cell death: an innocent convict?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

FoxO transcription factors promote autophagy in cardiomyocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Control of autophagy initiation by phosphoinositide 3-phosphatase Jumpy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

ERKs/p53 signal transduction pathway is involved in doxorubicin-induced apoptosis in H9c2 cells and cardiomyocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Autophagy is an adaptive response in desmin-related cardiomyopathy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Inducing autophagy harmlessly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

To be or not to be, the level of autophagy is the question: dual roles of autophagy in the survival response to starvation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Regulation of macroautophagy by mTOR and Beclin 1 complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Cardiac autophagy is a maladaptive response to hemodynamic stress

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Signalling and autophagy regulation in health, aging and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The pleiotropic role of autophagy: from protein metabolism to bactericide.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

A novel transgenic mouse model reveals deregulation of the ubiquitin-proteasome system in the heart by doxorubicin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Autophagy in chronically ischemic myocardium.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Methods for monitoring autophagy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Essential role of GATA-4 in cell survival and drug-induced cardiotoxicity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Antioxidants and cancer therapy: a systematic review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Congestive heart failure in patients treated with doxorubicin: a retrospective analysis of three trials

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The zinc finger-containing transcription factors GATA-4, -5, and -6. Ubiquitously expressed regulators of tissue-specific gene expression.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The protective role of manganese superoxide dismutase against adriamycin-induced acute cardiac toxicity in transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Cytoprotective agents for anthracyclines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

GATA4 inhibits expression of the tryptophan oxygenase gene by binding to the TATA box in fetal hepatocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Depletion of adenine nucleotide translocator protein in heart mitochondria from doxorubicin-treated rats--relevance for mitochondrial dysfunction

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

The transcription factors GATA4 and GATA6 regulate cardiomyocyte hypertrophy in vitro and in vivo.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

A randomized controlled trial assessing the prevention of doxorubicin cardiomyopathy by N-acetylcysteine

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Oxidative and non-oxidative mechanisms in the inactivation of cardiac mitochondrial electron transport chain components by doxorubicin.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Apoptosis in adriamycin cardiomyopathy and its modulation by probucol

3 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Preventive effect of erythropoietin on cardiac dysfunction in doxorubicin-induced cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Adriamycin-induced autophagic cardiomyocyte death plays a pathogenic role in a rat model of heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Divergent Signaling Pathways Converge on GATA4 to Regulate Cardiac Hypertrophic Gene Expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Cardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte Viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Thyroid hormone activates Akt and prevents serum starvation-induced cell death in neonatal rat cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Doxorubicin cardiac dysfunction: effects on calcium regulatory proteins, sarcoplasmic reticulum, and triiodothyronine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Life and death partners: apoptosis, autophagy and the cross-talk between them

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.070037

Attenuation of doxorubicin chronic toxicity in metallothionein-overexpressing transgenic mouse heart

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804228

Suppression of doxorubicin cardiotoxicity by overexpression of catalase in the heart of transgenic mice

27 November 2018

1 reference

12 December 2020

Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cells

1 reference

12 December 2020

Diphtheria toxin-induced autophagic cardiomyocyte death plays a pathogenic role in mouse model of heart failure

1 reference

12 December 2020

Anthracyclines induce calpain-dependent titin proteolysis and necrosis in cardiomyocytes

1 reference

12 December 2020

Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosis

1 reference

12 December 2020

Doxorubicin-induced cardiomyopathy

1 reference

12 December 2020

Clinical and pharmacologic investigation of the effects of alpha-tocopherol on adriamycin cardiotoxicity

1 reference

12 December 2020

Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo

1 reference

12 December 2020

Anthracycline-induced cardiomyopathy is manifested in decreased protein synthesis, impaired intracellular regeneration, and non-necrotic death of cardiomyocytes

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M109.070037

1 reference

2468506

2468506

1 reference

1 reference

1 reference