The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats (Q28579415)

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English	The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats	scientific journal article

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scholarly article

1 reference

31 January 2017

The cannabinoid receptor-1 antagonist rimonabant inhibits platelet activation and reduces pro-inflammatory chemokines and leukocytes in Zucker rats (English)

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31 January 2017

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cannabinoid receptor

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white blood cell

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based on heuristic

inferred from title

author name string

A. Schäfer

1

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31 January 2017

J. Pfrang

2

1 reference

31 January 2017

J. Neumüller

3

1 reference

31 January 2017

S. Fiedler

4

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31 January 2017

G. Ertl

5

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31 January 2017

J. Bauersachs

6

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31 January 2017

language of work or name

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publication date

1 July 2008

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31 January 2017

British Journal of Pharmacology

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31 January 2017

154

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31 January 2017

1047–1054

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31 January 2017

5

1 reference

31 January 2017

Long term pharmacotherapy for obesity and overweight: updated meta-analysis.

1 reference

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17 March 2017

Effects of Bariatric Surgery on Mortality in Swedish Obese Subjects

1 reference

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17 March 2017

Prevalence of overweight and obesity in the United States, 1999-2004

1 reference

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17 March 2017

Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesion

1 reference

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Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor

1 reference

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17 March 2017

Inflammation, atherosclerosis, and coronary artery disease

1 reference

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7 April 2017

Inflammation in atherosclerosis

1 reference

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Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction

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Endocannabinoids and related N-acylethanolamines in the control of appetite and energy metabolism: emergence of new molecular players

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29 September 2017

CB2-receptor stimulation attenuates TNF-alpha-induced human endothelial cell activation, transendothelial migration of monocytes, and monocyte-endothelial adhesion

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29 September 2017

Effect of rimonabant, a cannabinoid-1 receptor blocker, on weight and cardiometabolic risk factors in overweight or obese patients: RIO-North America: a randomized controlled trial

1 reference

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29 September 2017

Chemokines as potential therapeutic targets in atherosclerosis

1 reference

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29 September 2017

Platelets in inflammation and atherogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

29 September 2017

Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

29 September 2017

Platelets and chemokines in atherosclerosis: partners in crime

1 reference

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29 September 2017

Rimonabant--a selective CB1 antagonist

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

29 September 2017

Mechanisms of leukocyte recruitment to atherosclerotic lesions: future prospects

1 reference

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29 September 2017

Role of cannabinoid receptors in inhibiting macrophage costimulatory activity

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29 September 2017

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

1 reference

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29 September 2017

Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury

1 reference

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29 September 2017

Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

29 September 2017

Acarbose treatment and the risk of cardiovascular disease and hypertension in patients with impaired glucose tolerance: the STOP-NIDDM trial

1 reference

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3 June 2018

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

3 June 2018

RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.

1 reference

https://api.crossref.org/works/10.1038%2FBJP.2008.158

21 January 2018

Blockade of cannabinoid CB1 receptors improves renal function, metabolic profile, and increased survival of obese Zucker rats

1 reference

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27 November 2018

Chemokine fractalkine mediates leukocyte recruitment to inflammatory endothelial cells in flowing whole blood: a critical role for P-selectin expressed on activated platelets.

1 reference

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27 November 2018

Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary: The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

27 November 2018

Effects of rimonabant on metabolic risk factors in overweight patients with dyslipidemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

27 November 2018

Long-term cardiovascular consequences of obesity: 20-year follow-up of more than 15 000 middle-aged men and women (the Renfrew–Paisley study)

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2451057

27 November 2018

The anti-obesity effect of rimonabant is associated with an improved serum lipid profile

1 reference

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27 November 2018

Reduced vascular NO bioavailability in diabetes increases platelet activation in vivo

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Rapid regulation of platelet activation in vivo by nitric oxide

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Antagonism of RANTES receptors reduces atherosclerotic plaque formation in mice

1 reference

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Enhanced in vivo platelet adhesion in vasodilator-stimulated phosphoprotein (VASP)-deficient mice

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Inhibition of platelet activation in congestive heart failure by aldosterone receptor antagonism and ACE inhibition.

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Endothelium-dependent and -independent relaxation and VASP serines 157/239 phosphorylation by cyclic nucleotide-elevating vasodilators in rat aorta.

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Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

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Efficacy and tolerability of rimonabant in overweight or obese patients with type 2 diabetes: a randomised controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble guanylyl cyclase activation with HMR1766 attenuates platelet activation in diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved endothelial function and reduced platelet activation by chronic HMG-CoA-reductase inhibition with rosuvastatin in rats with streptozotocin-induced diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased platelet activation in young Zucker rats with impaired glucose tolerance is improved by acarbose

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial dysfunction, impaired endogenous platelet inhibition and platelet activation in diabetes and atherosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18469848

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/BJP.2008.158

1 reference

31 January 2017

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31 January 2017

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