Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells (Q28577298)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10964954%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10964954%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

0 references

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1 reference

S Lev

3

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author name string

D Tian

series ordinal

1

1 reference

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9 November 2019

V Litvak

series ordinal

2

1 reference

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9 November 2019

language of work or name

English

0 references

publication date

1 September 2000

2 references

31 January 2017

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9 November 2019

published in

Journal of Neuroscience

2 references

31 January 2017

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9 November 2019

volume

20

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31 January 2017

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9 November 2019

page(s)

6478-6487

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9 November 2019

issue

17

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31 January 2017

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GM-CSF promotes proliferation of human fetal and adult microglia in primary cultures

9 November 2019

cites work

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Chemokines induce migration and changes in actin polymerization in adult rat brain microglia and a human fetal microglial cell line in vitro

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The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathways

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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Identification of a new Pyk2 isoform implicated in chemokine and antigen receptor signaling.

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The effects of dextromethorphan on kainic acid-induced seizures in the rat

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Activation of Pyk2 by stress signals and coupling with JNK signaling pathway

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Reversible middle cerebral artery occlusion without craniectomy in rats

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Microglia: a sensor for pathological events in the CNS

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Identification of microglial signal transduction pathways mediating a neurotoxic response to amyloidogenic fragments of beta-amyloid and prion proteins

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Immunocytochemical localization of CR3 complement receptors with OX-42 in amoeboid microglia in postnatal rats

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Colony-stimulating factors as promoters of ameboid microglia

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Characterization of microglia and macrophages in the central nervous system of rats: definition of the differential expression of molecules using standard and novel monoclonal antibodies in normal CNS and in four models of parenchymal reaction.

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Proline-rich tyrosine kinase-2 activation by beta 1 integrin fibronectin receptor cross-linking and association with paxillin in human natural killer cells

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12 December 2020

Reactive microglia in cerebral ischaemia: an early mediator of tissue damage?

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12 December 2020

Beta-chemokine receptor CCR5 signals via the novel tyrosine kinase RAFTK

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12 December 2020

Neuroprotective interaction effects of NMDA and AMPA receptor antagonists in an in vitro model of cerebral ischemia.

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12 December 2020

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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12 December 2020

Phosphotyrosine antibodies specifically label ameboid microglia in vitro and ramified microglia in vivo.

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12 December 2020

FAK and PYK2/CAKbeta in the nervous system: a link between neuronal activity, plasticity and survival?

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12 December 2020

T cell receptor engagement induces tyrosine phosphorylation of FAK and Pyk2 and their association with Lck.

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12 December 2020

Activation of a novel calcium-dependent protein-tyrosine kinase. Correlation with c-Jun N-terminal kinase but not mitogen-activated protein kinase activation

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12 December 2020

Signal transduction through MAP kinase cascades

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12 December 2020

Heterogeneity of the microglial response in photochemically induced focal ischemia of the rat cerebral cortex.

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12 December 2020

Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

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12 December 2020

Induction of apoptosis signal regulating kinase 1 (ASK1) after spinal cord injury in rats: possible involvement of ASK1-JNK and -p38 pathways in neuronal apoptosis

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12 December 2020

The p38 signal transduction pathway: activation and function

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12 December 2020

Prevention of neuronal apoptosis by phorbol ester-induced activation of protein kinase C: blockade of p38 mitogen-activated protein kinase

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12 December 2020

Cytosolic Ca2+ changes during in vitro ischemia in rat hippocampal slices: major roles for glutamate and Na+-dependent Ca2+ release from mitochondria.

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12 December 2020

Spreading depression induces expression of calcium-independent protein kinase C subspecies in ischaemia-sensitive cortical layers: regulation by N-methyl-D-aspartate receptors and glucocorticoids.

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12 December 2020

Signaling through focal adhesion kinase

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12 December 2020

Depolarization and neurotransmitters increase neuronal protein tyrosine phosphorylation.

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12 December 2020

From receptors to stress-activated MAP kinases

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12 December 2020

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12 December 2020

Protein tyrosine kinase Pyk2 mediates the Jak-dependent activation of MAPK and Stat1 in IFN-gamma, but not IFN-alpha, signaling

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12 December 2020

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

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12 December 2020

Activation of p38 mitogen-activated protein kinase by PYK2/related adhesion focal tyrosine kinase-dependent mechanism

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12 December 2020

Microglial tyrosine phosphorylation systems in normal and degenerating brain.

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12 December 2020

Integrin signalling and tyrosine phosphorylation: just the FAKs?

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12 December 2020

Rat middle cerebral artery occlusion using an intraluminal thread technique

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12 December 2020

Activation of p38MAPK in microglia after ischemia.

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12 December 2020

FAK+ and PYK2/CAKbeta, two related tyrosine kinases highly expressed in the central nervous system: similarities and differences in the expression pattern

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12 December 2020

Ischemia-induced slowly progressive neuronal damage in the rat brain

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12 December 2020

10.1523/JNEUROSCI.20-17-06478.2000

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10964954%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10964954%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

2 references

31 January 2017