Knocking down HMGB1 using dendrimer-delivered siRNA unveils its key role in NMDA-induced autophagy in rat cortical neurons (Q28575459)

ORCID Public Data File 2021

author name string

María D. Pérez-Carrión

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1

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31 January 2017

1 October 2013

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31 January 2017

Pharmaceutical Research

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31 January 2017

30

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31 January 2017

10

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31 January 2017

2584–2595

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31 January 2017

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Autophagy for tissue homeostasis and neuroprotection

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Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons.

21 January 2018

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Autophagy gone awry in neurodegenerative diseases

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Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

21 January 2018

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Assays for cytochrome c release from mitochondria during apoptosis

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The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.

21 January 2018

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An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

21 January 2018

1 reference

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Receptor for advanced glycation end products (RAGE) signaling induces CREB-dependent chromogranin expression during neuronal differentiation

21 January 2018

1 reference

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High-mobility group box 1 (HMGB1) protein: friend and foe.

21 January 2018

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New EMBO members' review: the double life of HMGB1 chromatin protein: architectural factor and extracellular signal

21 January 2018

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HMG chromosomal proteins in development and disease

21 January 2018

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High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes

21 January 2018

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Hydrogen peroxide stimulates macrophages and monocytes to actively release HMGB1

21 January 2018

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Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

21 January 2018

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Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

21 January 2018

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High-mobility group box 1, oxidative stress, and disease

21 January 2018

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Gene silencing through RNA interference (RNAi) in vivo: strategies based on the direct application of siRNAs

21 January 2018

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Barriers to non-viral vector-mediated gene delivery in the nervous system

21 January 2018

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Nonviral vectors for the delivery of small interfering RNAs to the CNS.

21 January 2018

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Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death

21 January 2018

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HIF-1α is neuroprotective during the early phases of mild hypoxia in rat cortical neurons.

21 January 2018

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Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line.

21 January 2018

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Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1alpha in early chemical hypoxia-mediated neurotoxicity

21 January 2018

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Enhanced docetaxel-mediated cytotoxicity in human prostate cancer cells through knockdown of cofilin-1 by carbon nanohorn delivered siRNA.

21 January 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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How to interpret LC3 immunoblotting

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Excitotoxicity and the NMDA receptor--still lethal after eight years

21 January 2018

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Excitatory amino acids as a final common pathway for neurologic disorders.

21 January 2018

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Calcium and neurodegeneration

21 January 2018

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Antibodies against chromosomal HMG proteins stain the cytoplasm of mammalian cells

21 January 2018

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The nuclear protein HMGB1 is secreted by monocytes via a non-classical, vesicle-mediated secretory pathway

21 January 2018

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HMGB1, a novel cytokine-like mediator linking acute neuronal death and delayed neuroinflammation in the postischemic brain.

21 January 2018

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Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

21 January 2018

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RNAi therapeutics: principles, prospects and challenges

21 January 2018

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Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice

21 January 2018

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

21 January 2018

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Mitochondrial depolarization in glutamate-stimulated neurons: an early signal specific to excitotoxin exposure

21 January 2018

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12 December 2020

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice

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A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation.

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Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation

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Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

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Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment

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Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

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Denaturation studies on bovine pancreatic ribonuclease. Effect of trichloroacetic acid

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Efficient, non-toxic hybrid PPV-PAMAM dendrimer as a gene carrier for neuronal cells

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