Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists (Q28575016)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16540562%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16540562%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

0 references

1 reference

Alokesh Ghosal

2

2 references

31 January 2017

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18 January 2020

Mark L Mayer

series ordinal

1

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18 January 2020

Nigel P Dolman

series ordinal

3

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18 January 2020

David E Jane

series ordinal

4

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18 January 2020

language of work or name

English

0 references

publication date

1 March 2006

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18 January 2020

published in

Journal of Neuroscience

2 references

31 January 2017

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18 January 2020

volume

26

2 references

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18 January 2020

issue

11

2 references

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18 January 2020

page(s)

2852-2861

1 reference

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The glutamate receptor ion channels

18 January 2020

cites work

1 reference

12 December 2020

Automated MAD and MIR structure solution

1 reference

12 December 2020

Functional characterization of a potassium-selective prokaryotic glutamate receptor

1 reference

12 December 2020

Ligands for glutamate receptors: design and therapeutic prospects

1 reference

12 December 2020

Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core

1 reference

12 December 2020

Use of TLS parameters to model anisotropic displacements in macromolecular refinement

1 reference

12 December 2020

Subunit composition of kainate receptors in hippocampal interneurons

1 reference

12 December 2020

Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state

1 reference

12 December 2020

Mechanism of glutamate receptor desensitization

1 reference

12 December 2020

Structural mobility of the extracellular ligand-binding core of an ionotropic glutamate receptor. Analysis of NMR relaxation dynamics

1 reference

12 December 2020

Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate

1 reference

12 December 2020

Competitive antagonism of AMPA receptors by ligands of different classes: crystal structure of ATPO bound to the GluR2 ligand-binding core, in comparison with DNQX

1 reference

12 December 2020

Structural Model of the N-Methyl-D-aspartate Receptor Glycine Site Probed by Site-directed Chemical Coupling

1 reference

12 December 2020

Tuning activation of the AMPA-sensitive GluR2 ion channel by genetic adjustment of agonist-induced conformational changes

1 reference

12 December 2020

Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core

1 reference

12 December 2020

Structural basis for partial agonist action at ionotropic glutamate receptors

1 reference

12 December 2020

Selective agonist binding of (S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) and 2S-(2alpha,3beta,4beta)-2-carboxy-4-(1-methylethenyl)-3-pyrrolidineacetic acid (kainate) receptors: a molecular modeling study

1 reference

12 December 2020

Regulation of AMPA receptor gating by ligand binding core dimers

1 reference

12 December 2020

Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands

1 reference

12 December 2020

Structure and function of glutamate receptor ion channels

1 reference

12 December 2020

Characterisation of UBP296: a novel, potent and selective kainate receptor antagonist

1 reference

12 December 2020

Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

1 reference

12 December 2020

Crystal structure of the kainate receptor GluR5 ligand-binding core in complex with (S)-glutamate

1 reference

12 December 2020

Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity

1 reference

12 December 2020

Microsecond-to-millisecond conformational dynamics demarcate the GluR2 glutamate receptor bound to agonists glutamate, quisqualate, and AMPA.

1 reference

12 December 2020

Likelihood-enhanced fast translation functions

1 reference

12 December 2020

A molecular viewer for the analysis of TLS rigid-body motion in macromolecules

1 reference

12 December 2020

Glutamate receptor ion channels

1 reference

12 December 2020

Mechanism of partial agonist action at the NR1 subunit of NMDA receptors

1 reference

12 December 2020

Mechanism of positive allosteric modulators acting on AMPA receptors

1 reference

12 December 2020

Binding site flexibility: molecular simulation of partial and full agonists within a glutamate receptor.

1 reference

12 December 2020

Protein flexibility using constraints from molecular dynamics simulations.

1 reference

12 December 2020

Subunit arrangement and function in NMDA receptors

1 reference

12 December 2020

Synthesis and pharmacology of willardiine derivatives acting as antagonists of kainate receptors.

1 reference

12 December 2020

Electron-density map interpretation

1 reference

12 December 2020

Raster3D: photorealistic molecular graphics

1 reference

12 December 2020

Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists.

1 reference

12 December 2020

Atomic structure and specificity of bacterial periplasmic receptors for active transport and chemotaxis: variation of common themes

1 reference

12 December 2020

An extensively modified version of MolScript that includes greatly enhanced coloring capabilities

1 reference

12 December 2020

The tetrameric structure of a glutamate receptor channel

1 reference

12 December 2020

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

12 December 2020

10.1523/JNEUROSCI.0123-06.2005

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4485347

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16540562%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

4485347

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16540562%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

2 references

Consolidated OpenCitations Corpus – April 2017

4485347