Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells (Q28574877)

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object named as

Chantal Mathieu

1 reference

31 January 2017

Joanne Rasschaert

1

1 reference

31 January 2017

Laurence Ladrière

2

1 reference

31 January 2017

Maryse Urbain

3

1 reference

31 January 2017

Zeynep Dogusan

4

1 reference

31 January 2017

Bitty Katabua

5

1 reference

31 January 2017

Shintaro Sato

6

1 reference

31 January 2017

Conny Gysemans

8

1 reference

31 January 2017

Decio L. Eizirik

Journal of Biological Chemistry

10

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31 January 2017

language of work or name

English

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publication date

7 October 2005

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31 January 2017

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31 January 2017

280

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31 January 2017

40

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31 January 2017

33984–33991

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31 January 2017

The role of viruses in human diabetes.

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Enteroviruses and type 1 diabetes mellitus.

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Noncytolytic control of viral infections by the innate and adaptive immune response

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Enterovirus infection in human pancreatic islet cells, islet tropism in vivo and receptor involvement in cultured islet beta cells

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A new look at viruses in type 1 diabetes.

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The role of viruses in type I diabetes: two distinct cellular and molecular pathogenic mechanisms of virus-induced diabetes in animals

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Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis

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When two strands are better than one: the mediators and modulators of the cellular responses to double-stranded RNA.

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PKR; a sentinel kinase for cellular stress

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A double-stranded RNA-activated protein kinase-dependent pathway mediating stress-induced apoptosis

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Effect of interferon and double-stranded RNA on B-cell function in mouse islets of Langerhans

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Inferences, questions and possibilities in Toll-like receptor signalling

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IRF3 mediates a TLR3/TLR4-specific antiviral gene program

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Toll-like receptor signalling

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Recognition of double-stranded RNA and activation of NF-kappaB by Toll-like receptor 3

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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Toll-like receptor 3: a link between toll-like receptor, interferon and viruses

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Toll-like receptor 3 mediates a more potent antiviral response than Toll-like receptor 4

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Analysis of double-stranded RNA-induced apoptosis pathways using interferon-response noninducible small interfering RNA expression vector library

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Evidence of expression of endotoxin receptors CD14, toll-like receptors TLR4 and TLR2 and associated molecule MD-2 and of sensitivity to endotoxin (LPS) in islet beta cells

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The effect of innate immunity on autoimmune diabetes and the expression of Toll-like receptors on pancreatic islets.

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Coxsackievirus B4-induced cytokine production in pancreatic cells is mediated through toll-like receptor 4.

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Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

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Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

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Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

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Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

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Expression of adiponectin receptors in pancreatic beta cells

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IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

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A single amino acid substitution in the v-Eyk intracellular domain results in activation of Stat3 and enhances cellular transformation.

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The Toll-IL-1 receptor adaptor family grows to five members.

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Transcriptional signaling by double-stranded RNA: role of TLR3.

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Signaling of apoptosis through TLRs critically involves toll/IL-1 receptor domain-containing adapter inducing IFN-beta, but not MyD88, in bacteria-infected murine macrophages

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Mechanisms of the TRIF-induced interferon-stimulated response element and NF-kappaB activation and apoptosis pathways

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Expression of a novel murine type I IFN in the pancreatic islets induces diabetes in mice

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STAT-1: a novel regulator of apoptosis

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The interferon in TLR signaling: more than just antiviral

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Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease

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IFN beta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.

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TLR4, but not TLR2, signals autoregulatory apoptosis of cultured microglia: a critical role of IFN-beta as a decision maker

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