FGF21 is an endocrine signal of protein restriction (Q28572009)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25133427%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Christopher D Morrison

11

1 reference

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4 June 2020

7

Heike Münzberg

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25133427%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

4

Leanne M Redman

1 reference

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4 June 2020

author name string

Tara M Henagan

2

1 reference

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4 June 2020

Diana C Albarado

3

1 reference

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4 June 2020

George A Bray

5

1 reference

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4 June 2020

Robert C Noland

6

1 reference

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4 June 2020

Susan M Hutson

8

1 reference

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4 June 2020

Thomas W Gettys

9

1 reference

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4 June 2020

Michael W Schwartz

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25133427%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

4 June 2020

language of work or name

English

0 references

publication date

1 September 2014

1 reference

31 January 2017

2 references

31 January 2017

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4 June 2020

volume

124

2 references

31 January 2017

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4 June 2020

issue

9

2 references

31 January 2017

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4 June 2020

page(s)

3913-3922

1 reference

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describes a project that uses

4 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4153701/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice

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Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.

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Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine

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Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation

29 September 2017

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FGF21 regulates metabolism and circadian behavior by acting on the nervous system

29 September 2017

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FGF21 contributes to neuroendocrine control of female reproduction

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Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice

29 September 2017

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Genome-wide meta-analysis of observational studies shows common genetic variants associated with macronutrient intake

29 September 2017

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Novel locus including FGF21 is associated with dietary macronutrient intake

29 September 2017

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Circulating fibroblast growth factors as metabolic regulators--a critical appraisal

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The starvation hormone, fibroblast growth factor-21, extends lifespan in mice.

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FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis

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Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis

29 September 2017

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29 September 2017

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

29 September 2017

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29 September 2017

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Circulating fibroblast growth factor-21 is elevated in impaired glucose tolerance and type 2 diabetes and correlates with muscle and hepatic insulin resistance.

3 June 2018

1 reference

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Geometric analysis of macronutrient selection in the rat.

3 June 2018

1 reference

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The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes

3 June 2018

1 reference

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Growth hormone stimulates transcription of the fibroblast growth factor 21 gene in the liver through the signal transducer and activator of transcription 5.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Circulating fibroblast growth factor 21 is induced by peroxisome proliferator-activated receptor agonists but not ketosis in man.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARalpha activation in man.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

27 November 2018

1 reference

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Protein-leverage in mice: the geometry of macronutrient balancing and consequences for fat deposition.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Preservation of liver protein synthesis during dietary leucine deprivation occurs at the expense of skeletal muscle mass in mice deleted for eIF2 kinase GCN2.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4153701

Effects of age on the feeding response to moderately low dietary protein in rats

27 November 2018

1 reference

12 December 2020

Protein selection, food intake, and body composition in response to the amount of dietary protein

1 reference

12 December 2020

Mechanisms of thermogenesis induced by low protein diets

1 reference

12 December 2020

Influence of carbohydrate and fat intake on diet-induced thermogenesis and brown fat activity in rats fed low protein diets

1 reference

12 December 2020

Free and protein-bound amino acids in sow's colostrum and milk

1 reference

12 December 2020

Low protein diets increase neuropeptide Y gene expression in the basomedial hypothalamus of rats

1 reference

12 December 2020

Essential amino acids regulate fatty acid synthase expression through an uncharged transfer RNA-dependent mechanism

1 reference

12 December 2020

Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice

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12 December 2020

Identifiers

DOI

10.1172/JCI74915

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25133427%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25133427%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

2 references