Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'? (Q28567222)

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18 January 2020

title

Prenatal programming of hepatocyte nuclear factor 4alpha in the rat: A key mechanism in the 'foetal origins of hyperglycaemia'? (English)

2 references

31 January 2017

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18 January 2020

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4

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18 January 2020

author name string

M J Nyirenda

1

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18 January 2020

S Dean

2

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18 January 2020

V Lyons

3

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18 January 2020

J R Seckl

5

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18 January 2020

publication date

29 March 2006

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18 January 2020

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31 January 2017

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18 January 2020

volume

49

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18 January 2020

page(s)

1412-1420

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issue

6

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https://scigraph.springernature.com/pub.10.1007/s00125-006-0188-5

18 January 2020

exact match

0 references

cites work

Phosphoenolpyruvate carboxykinase and pyruvate carboxylase in developing rat liver

1 reference

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The development of gluconeogenesis in rat liver. Effects of glucagon and ether

21 January 2018

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Tissue-specific regulation of mouse hepatocyte nuclear factor 4 expression

21 January 2018

1 reference

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Human hepatocyte nuclear factor 4 isoforms are encoded by distinct and differentially expressed genes

21 January 2018

1 reference

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Hormonal regulation of hepatic P-enolpyruvate carboxykinase (GTP) during development

21 January 2018

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12 December 2020

A transcriptional hierarchy involved in mammalian cell-type specification

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12 December 2020

Glucocorticoid exposure in late gestation permanently programs rat hepatic phosphoenolpyruvate carboxykinase and glucocorticoid receptor expression and causes glucose intolerance in adult offspring.

1 reference

12 December 2020

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

12 December 2020

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

1 reference

12 December 2020

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)

1 reference

12 December 2020

Zonal distribution of transcripts of four hepatic transcription factors in the mature rat liver

1 reference

12 December 2020

Fuels, Hormones, and Liver Metabolism at Term and during the Early Postnatal Period in the Rat

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12 December 2020

Analysis of gene expression profile induced by hepatocyte nuclear factor 4alpha in hepatoma cells using an oligonucleotide microarray

1 reference

12 December 2020

Prenatal glucocorticoid exposure leads to offspring hyperglycaemia in the rat: studies with the 11 beta-hydroxysteroid dehydrogenase inhibitor carbenoxolone.

1 reference

12 December 2020

Vitamin A depletion is associated with low phosphoenolpyruvate carboxykinase mRNA levels during late fetal development and at birth in mice

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12 December 2020

Role of accessory factors and steroid receptor coactivator 1 in the regulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

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Regulators of fetal liver differentiation in vitro

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Gene regulation in rodent hepatocytes during development, differentiation and disease

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In utero programming of chronic disease

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Regulation of a transcription factor network required for differentiation and metabolism.

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12 December 2020

Control of pancreas and liver gene expression by HNF transcription factors

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12 December 2020

A common polymorphism in the upstream promoter region of the hepatocyte nuclear factor-4 alpha gene on chromosome 20q is associated with type 2 diabetes and appears to contribute to the evidence for linkage in an ashkenazi jewish population.

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12 December 2020

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

1 reference

12 December 2020

Programming hyperglycaemia in the rat through prenatal exposure to glucocorticoids-fetal effect or maternal influence?

1 reference

12 December 2020

Hepatic expression of CCAAT/enhancer binding protein alpha: hormonal and metabolic regulation in rats.

1 reference

12 December 2020

Glucocorticoids regulate transcription of the gene for phosphoenolpyruvate carboxykinase in the liver via an extended glucocorticoid regulatory unit

1 reference

12 December 2020

Contribution of gluconeogenesis to overall glucose output in diabetic and nondiabetic men.

1 reference

12 December 2020

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

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12 December 2020

Dexamethasone in the last week of pregnancy attenuates hippocampal glucocorticoid receptor gene expression and elevates blood pressure in the adult offspring in the rat.

1 reference

12 December 2020

Transgenic mice overexpressing phosphoenolpyruvate carboxykinase develop non-insulin-dependent diabetes mellitus.

1 reference

12 December 2020

Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4

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12 December 2020

An alternative splice variant of the tissue specific transcription factor HNF4alpha predominates in undifferentiated murine cell types

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12 December 2020

T130I mutation in HNF-4alpha gene is a loss-of-function mutation in hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjects

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12 December 2020

Genotype/phenotype relationships in HNF-4alpha/MODY1: haploinsufficiency is associated with reduced apolipoprotein (AII), apolipoprotein (CIII), lipoprotein(a), and triglyceride levels

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12 December 2020

Central 5,7-dihydroxytryptamine lesions decrease hippocampal glucocorticoid and mineralocorticoid receptor messenger ribonucleic Acid expression

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12 December 2020

An enhancer element 6 kb upstream of the mouse HNF4alpha1 promoter is activated by glucocorticoids and liver-enriched transcription factors

1 reference

12 December 2020

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

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12 December 2020

Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing

1 reference

12 December 2020

Developmental plasticity and human health.

1 reference

12 December 2020

10.1007/S00125-006-0188-5

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16570165%20AND%20SRC:MED&resulttype=core&format=json

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18 January 2020

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2 references

31 January 2017