A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme (Q28566987)

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English	A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme	scientific journal article

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scholarly article

1 reference

31 January 2017

A single amino acid change (substitution of the conserved Glu-590 with alanine) in the C-terminal domain of rat liver carnitine palmitoyltransferase I increases its malonyl-CoA sensitivity close to that observed with the muscle isoform of the enzyme (English)

1 reference

31 January 2017

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author name string

Laura Napal

1

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31 January 2017

Jia Dai

2

1 reference

31 January 2017

Michelle Treber

3

1 reference

31 January 2017

Diego Haro

4

1 reference

31 January 2017

Pedro F. Marrero

5

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31 January 2017

Gebre Woldegiorgis

6

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31 January 2017

language of work or name

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publication date

5 September 2003

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31 January 2017

Journal of Biological Chemistry

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31 January 2017

278

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31 January 2017

36

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31 January 2017

34084–34089

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31 January 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Are the beta-cell signaling molecules malonyl-CoA and cystolic long-chain acyl-CoA implicated in multiple tissue defects of obesity and NIDDM?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Functional characterization of mitochondrial carnitine palmitoyltransferases I and II expressed in the yeast Pichia pastoris

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Deletion of the conserved first 18 N-terminal amino acid residues in rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA sensitivity and binding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high-affinity binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Substitution of glutamate-3, valine-19, leucine-23, and serine-24 with alanine in the N-terminal region of human heart muscle carnitine palmitoyltransferase I abolishes malonyl CoA inhibition and binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Carnitine palmitoyltransferase. Activation by palmitoyl-CoA and inactivation by malonyl-CoA.

1 reference

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Identification of lipid-accessible sites on the nephrops 16-kDa proteolipid incorporated into a hybrid vacuolar H(+)-ATPase: site-directed labeling with N-(1-Pyrenyl)cyclohexylcarbodiimide and fluorescence quenching analysis.

1 reference

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21 January 2018

Identification by mutagenesis of conserved arginine and glutamate residues in the C-terminal domain of rat liver carnitine palmitoyltransferase I that are important for catalytic activity and malonyl-CoA sensitivity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Identification by mutagenesis of a conserved glutamate (Glu487) residue important for catalytic activity in rat liver carnitine palmitoyltransferase II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Crystal structure of carnitine acetyltransferase and implications for the catalytic mechanism and fatty acid transport

1 reference

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21 January 2018

Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Expression and possible role of muscle-type carnitine palmitoyltransferase I during sperm development in the rat.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Mitochondrial carnitine palmitoyltransferase I isoform switching in the developing rat heart

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Reconstitution of highly expressed human heart muscle carnitine palmitoyltransferase I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

A single amino acid change (substitution of glutamate 3 with alanine) in the N-terminal region of rat liver carnitine palmitoyltransferase I abolishes malonyl-CoA inhibition and high affinity binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Identification by mutagenesis of conserved arginine and tryptophan residues in rat liver carnitine palmitoyltransferase I important for catalytic activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Identification of positive and negative determinants of malonyl-CoA sensitivity and carnitine affinity within the amino termini of rat liver- and muscle-type carnitine palmitoyltransferase I

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305826200

21 January 2018

Identifiers

10.1074/JBC.M305826200

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31 January 2017

1 reference

31 January 2017

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