SCLIP, a microtubule-destabilizing factor, interacts with RasGRF1 and inhibits its ability to promote Rac activation and neurite outgrowth (Q28564467)

GOA release 2020-03-11

Stathmin-like 3

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GOA release 2020-03-11

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Simona Baldassa

1

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31 January 2017

Nerina Gnesutta

2

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31 January 2017

Umberto Fascio

3

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31 January 2017

Emmapaola Sturani

4

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31 January 2017

Renata Zippel

Journal of Biological Chemistry

5

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31 January 2017

language of work or name

English

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publication date

26 January 2007

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31 January 2017

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31 January 2017

282

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31 January 2017

2333–2345

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31 January 2017

4

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31 January 2017

The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Ras-GRF, the activator of Ras, is expressed preferentially in mature neurons of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

A role for the Ras signalling pathway in synaptic transmission and long-term memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

ERK-dependent modulation of cerebellar synaptic plasticity after chronic Delta9-tetrahydrocannabinol exposure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Modulation of extracellular signal-regulated kinases cascade by chronic delta 9-tetrahydrocannabinol treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Ras/ERK signalling in cannabinoid tolerance: from behaviour to cellular aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Age-dependent participation of Ras-GRF proteins in coupling calcium-permeable AMPA glutamate receptors to Ras/Erk signaling in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Neurotrophin-dependent tyrosine phosphorylation of Ras guanine-releasing factor 1 and associated neurite outgrowth is dependent on the HIKE domain of TrkA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Activity-dependent interaction of the intracellular domain of rat trkA with intermediate filament proteins, the beta-6 proteasomal subunit, Ras-GRF1, and the p162 subunit of eIF3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

A novel SCG10-related gene uniquely expressed in the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Expression of stathmin family genes in human tissues: non-neural-restricted expression for SCLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The stathmin family -- molecular and biological characterization of novel mammalian proteins expressed in the nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Stathmin: a tubulin-sequestering protein which forms a ternary T2S complex with two tubulin molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Stathmin family proteins display specific molecular and tubulin binding properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Dissociation of the tubulin-sequestering and microtubule catastrophe-promoting activities of oncoprotein 18/stathmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Targeting of SCG10 to the area of the Golgi complex is mediated by its NH2-terminal region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Two separate motifs cooperate to target stathmin-related proteins to the Golgi complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Regulation and subcellular localization of the microtubule-destabilizing stathmin family phosphoproteins in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

SCG10 expresses growth-associated manner in developing rat brain, but shows a different pattern to p19/stathmin or GAP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The phosphoprotein stathmin is essential for nerve growth factor-stimulated differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Regulation of microtubule dynamics by the neuronal growth-associated protein SCG10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

RGS6 interacts with SCG10 and promotes neuronal differentiation. Role of the G gamma subunit-like (GGL) domain of RGS6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Role of the microtubule destabilizing proteins SCG10 and stathmin in neuronal growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Expression of Ras-GRF in the SK-N-BE neuroblastoma accelerates retinoic-acid-induced neuronal differentiation and increases the functional expression of the IRK1 potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

CDC25(Mm)/Ras-GRF1 regulates both Ras and Rac signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Depolarization-induced signaling to Ras, Rap1 and MAPKs in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Identification of in vitro phosphorylation sites in the growth cone protein SCG10. Effect Of phosphorylation site mutants on microtubule-destabilizing activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Differential phosphoprotein labeling (DIPPL), a method for comparing live cell phosphoproteomes using simultaneous analysis of (33)P- and (32)P-labeled proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Expression of two different products of CDC25Mm, a mammalian Ras activator, during development of mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Conserved microtubule-actin interactions in cell movement and morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Regulation of leading edge microtubule and actin dynamics downstream of Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The Ras-GRF1 exchange factor coordinates activation of H-Ras and Rac1 to control neuronal morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The role of the Rho GTPases in neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Clusterin interacts with SCLIP (SCG10-like protein) and promotes neurite outgrowth of PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

JNK1 phosphorylation of SCG10 determines microtubule dynamics and axodendritic length

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

The guanine nucleotide exchange factor RasGRF1 directly binds microtubules via DHPH2-mediated interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Characterization of STEF, a guanine nucleotide exchange factor for Rac1, required for neurite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Critical role for Kalirin in nerve growth factor signaling through TrkA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

Neurofibrillary tangle-associated alteration of stathmin in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200

SCG10, a neuron-specific growth-associated protein in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M604495200