Angiotensinogen (Q28563283)

http://www.ebi.ac.uk/interpro/protein/P01015

angiotensinogen

1 reference

stated in

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P01015

Serpin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

serine-type endopeptidase inhibitor activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

type 1 angiotensin receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

type 2 angiotensin receptor binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

5 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

14 February 2019

Characterisation of a thymic renin-angiotensin system in the transgenic m(Ren-2)27 rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

14 February 2019

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

Characterisation of a thymic renin-angiotensin system in the transgenic m(Ren-2)27 rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

No evidence for a local renin-angiotensin system in liver mitochondria

Parkinsons Disease Gene Ontology Initiative

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

renin-angiotensin regulation of aldosterone production

1 reference

14 February 2019

Mechanism of Ang II involvement in activation of NF-κB through phosphorylation of p65 during aging

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

Posttranscriptional control of BNP gene expression in angiotensin II-induced hypertension

regulation of heart rate

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

angiotensin-mediated drinking behavior

regulation of systemic arterial blood pressure by renin-angiotensin

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of extracellular matrix constituent secretion

1 reference

14 February 2019

Effects of Chinese herbal medicine Xuefu Zhuyu Decoction on angiotensin II-induced proliferation and extracellular matrix synthesis of rat cardiac fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

protein import into nucleus

1 reference

14 February 2019

Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

cellular sodium ion homeostasis

1 reference

14 February 2019

Renal angiotensin type 2 receptors mediate natriuresis via angiotensin III in the angiotensin II type 1 receptor-blocked rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

cell surface receptor signaling pathway

1 reference

14 February 2019

High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

activation of phospholipase C activity

1 reference

14 February 2019

AT-1 receptor and phospholipase C are involved in angiotensin III modulation of hypothalamic noradrenergic transmission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of cytosolic calcium ion concentration

1 reference

14 February 2019

Upregulation of a local renin-angiotensin system in the rat carotid body during chronic intermittent hypoxia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

ACE2 and ANG-(1-7) in the rat uterus during early and late gestation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

Mechanism of Ang II involvement in activation of NF-κB through phosphorylation of p65 during aging

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of blood pressure

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of cell population proliferation

1 reference

14 February 2019

Counteraction between angiotensin II and angiotensin-(1-7) via activating angiotensin type I and Mas receptor on rat renal mesangial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

Involvement of D1 dopamine receptors in the cognitive effects of angiotensin IV and des-Phe6 angiotensin IV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of signaling receptor activity

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of activation of Janus kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of endothelial cell migration

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of cardiac muscle hypertrophy

1 reference

14 February 2019

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of cardiac muscle cell apoptotic process

1 reference

14 February 2019

Mechanisms of Ghrelin anti-heart failure: inhibition of Ang II-induced cardiomyocyte apoptosis by down-regulating AT1R expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of cholesterol esterification

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

negative regulation of endopeptidase activity

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of neuron projection development

IBA

1 reference

14 February 2019

Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of norepinephrine secretion

1 reference

14 February 2019

AT-1 receptor and phospholipase C are involved in angiotensin III modulation of hypothalamic noradrenergic transmission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of phosphatidylinositol 3-kinase signaling

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

artery smooth muscle contraction

1 reference

14 February 2019

Methylglyoxal augments angiotensin II-induced contraction in rat isolated carotid artery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

response to muscle activity involved in regulation of muscle adaptation

1 reference

14 February 2019

Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

negative regulation of angiogenesis

1 reference

14 February 2019

Pregnancy protects against antiangiogenic and fibrogenic effects of angiotensin II in rat hearts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

negative regulation of cell growth

1 reference

14 February 2019

Angiotensin-(1-7) inhibits growth of cardiac myocytes through activation of the mas receptor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of protein metabolic process

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

Estrogen elicits dorsal root ganglion axon sprouting via a renin-angiotensin system.

response to estradiol

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of superoxide anion generation

1 reference

14 February 2019

Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

negative regulation of tissue remodeling

1 reference

14 February 2019

Impairment of cardiac function and remodeling induced by myocardial infarction in rats are attenuated by the nonpeptide angiotensin-(1-7) analog AVE 0991.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

14 February 2019

Involvement of D1 dopamine receptors in the cognitive effects of angiotensin IV and des-Phe6 angiotensin IV

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of renal sodium excretion

1 reference

14 February 2019

A role for the angiotensin IV/AT4 system in mediating natriuresis in the rat

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of renal sodium excretion

1 reference

14 February 2019

Casein-derived tripeptide Ile-Pro-Pro improves angiotensin-(1-7)- and bradykinin-induced rat mesenteric artery relaxation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of apoptotic process

1 reference

14 February 2019

Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis protects against lung fibrosis by inhibiting the MAPK/NF-κB pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of catalytic activity

1 reference

14 February 2019

AT-1 receptor and phospholipase C are involved in angiotensin III modulation of hypothalamic noradrenergic transmission

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of nitric oxide biosynthetic process

1 reference

14 February 2019

Evidence that the vasodilator angiotensin-(1-7)-Mas axis plays an important role in erectile function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of epidermal growth factor receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of insulin receptor signaling pathway

1 reference

14 February 2019

Angiotensin 1-7 improves insulin sensitivity by increasing skeletal muscle glucose uptake in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

Effects of Chinese herbal medicine Xuefu Zhuyu Decoction on angiotensin II-induced proliferation and extracellular matrix synthesis of rat cardiac fibroblasts

fibroblast proliferation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of fibroblast proliferation

1 reference

14 February 2019

Molecular characterization of angiotensin II--induced hypertrophy of cardiac myocytes and hyperplasia of cardiac fibroblasts. Critical role of the AT1 receptor subtype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of long-term neuronal synaptic plasticity

1 reference

14 February 2019

The effects of angiotensin IV analogs on long-term potentiation within the CA1 region of the hippocampus in vitro

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

smooth muscle cell proliferation

1 reference

14 February 2019

Involvement of vascular peroxidase 1 in angiotensin II-induced vascular smooth muscle cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of peptidyl-tyrosine phosphorylation

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

negative regulation of neurotrophin TRK receptor signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

stress-activated MAPK cascade

1 reference

14 February 2019

Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of calcium ion transport

1 reference

14 February 2019

Regulation of L-type inward calcium channel activity by captopril and angiotensin II via the phosphatidyl inositol 3-kinase pathway in cardiomyocytes from volume-overload hypertrophied rat hearts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of transmission of nerve impulse

1 reference

14 February 2019

Angiotensin-(1-7) attenuates the chronotropic response to angiotensin II via stimulation of PTEN in the spontaneously hypertensive rat neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

cell growth involved in cardiac muscle cell development

1 reference

14 February 2019

Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of protein tyrosine kinase activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

Angiotensin II increases periostin expression via Ras/p38 MAPK/CREB and ERK1/2/TGF-β1 pathways in cardiac fibroblasts

ERK1 and ERK2 cascade

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

uterine smooth muscle contraction

1 reference

14 February 2019

Assessment of biological activity of novel peptide analogues of angiotensin IV.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

cellular response to mechanical stimulus

1 reference

14 February 2019

Rac1 and RhoA differentially regulate angiotensinogen gene expression in stretched cardiac fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of branching involved in ureteric bud morphogenesis

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of extracellular matrix assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of gap junction assembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

regulation of cardiac conduction

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

cellular response to angiotensin

1 reference

14 February 2019

ROCK/NF-κB axis-dependent augmentation of angiotensinogen by angiotensin II in primary-cultured preglomerular vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of vascular associated smooth muscle cell proliferation

1 reference

14 February 2019

Cardamonin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and migration by downregulating p38 MAPK, Akt, and ERK phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of vascular associated smooth muscle cell migration

1 reference

14 February 2019

Cardamonin inhibits angiotensin II-induced vascular smooth muscle cell proliferation and migration by downregulating p38 MAPK, Akt, and ERK phosphorylation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of L-lysine import across plasma membrane

1 reference

14 February 2019

Angiotensin II stimulates system y+ and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of L-arginine import across plasma membrane

1 reference

14 February 2019

Angiotensin II stimulates system y+ and cationic amino acid transporter gene expression in cultured vascular smooth muscle cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

positive regulation of extrinsic apoptotic signaling pathway

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01015

1 reference

InterPro Release 71.0