Rabphilin 3A (Q28560922)

Rabphilin-3A

1 reference

Zinc finger, RING/FYVE/PHD-type

1 reference

C2 domain superfamily

1 reference

membrane protein

1 reference

inferred from GOA cell component → membrane

C2 domain, protein family

1 reference

Zinc finger, FYVE-related, protein family

1 reference

Synaptotagmin

1 reference

Rab-binding domain, protein family

1 reference

Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C

1 reference

17 November 2021

1 reference

17 November 2021

3 references

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

The C2A-C2B linker defines the high affinity Ca(2+) binding mode of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

7 references

9 May 2019

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Identification of a rabphilin-3A-interacting protein as GTP cyclohydrolase I in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Rabphilin regulates SNARE-dependent re-priming of synaptic vesicles for fusion

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

calcium-dependent phospholipid binding

TAS

1 reference

9 May 2019

The C2A-C2B linker defines the high affinity Ca(2+) binding mode of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

phosphatidylinositol-4,5-bisphosphate binding

1 reference

9 May 2019

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

Characterization of rabphilin phosphorylation using phospho-specific antibodies

phosphate ion binding

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

protein-containing complex binding

1 reference

9 May 2019

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

inositol 1,4,5 trisphosphate binding

IEA

1 reference

9 May 2019

Structural determinants for Ca2+ and phosphatidylinositol 4,5-bisphosphate binding by the C2A domain of rabphilin-3A

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Novel localization of Rab3D in rat intestinal goblet cells and Brunner's gland acinar cells suggests a role in early Golgi trafficking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

The Rab27 effector Rabphilin, unlike Granuphilin and Noc2, rapidly exchanges between secretory granules and cytosol in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

3 references

9 May 2019

Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

9 May 2019

Developmental regulation and specific brain distribution of phosphorabphilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

extrinsic component of membrane

1 reference

9 May 2019

Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

The Rab27 effector Rabphilin, unlike Granuphilin and Noc2, rapidly exchanges between secretory granules and cytosol in PC12 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

synaptic vesicle membrane

1 reference

8 April 2019

Synaptic targeting of rabphilin-3A, a synaptic vesicle Ca2+/phospholipid-binding protein, depends on rab3A/3C

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

Localization of Rabphilin-3A on the synaptic vesicle

neuromuscular junction

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

protein-containing complex

1 reference

9 May 2019

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Identification of a novel protein complex containing annexin A4, rabphilin and synaptotagmin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

extrinsic component of synaptic vesicle membrane

3 references

1 reference

9 May 2019

Localization of Rabphilin-3A on the synaptic vesicle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

8 April 2019

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex

postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

intracellular protein transport

IEA

biological process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

Developmental regulation and specific brain distribution of phosphorabphilin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

dendritic spine organization

IEA

1 reference

9 May 2019

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709

regulation of NMDA receptor activity

IMP

1 reference

9 May 2019

Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P47709