ERBB receptor feedback inhibitor 1 (Q28560421)

IPI

protein kinase binding

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

1 reference

14 February 2019

Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

extrinsic component of cytoplasmic side of plasma membrane

IEA

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of epidermal growth factor-activated receptor activity

IBA

biological process

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of interleukin-1 beta production

IDA

1 reference

14 February 2019

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

cellular response to insulin stimulus

IMP

1 reference

14 February 2019

Regulation of Gene33 expression by insulin requires MEK-ERK activation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of collagen biosynthetic process

1 reference

14 February 2019

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

cellular response to platelet-derived growth factor stimulus

IMP

1 reference

14 February 2019

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of epidermal growth factor receptor signaling pathway

3 references

14 February 2019

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

2 references

regulation of keratinocyte differentiation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

lung alveolus development

IBA

negative regulation of peptidyl-tyrosine phosphorylation

IEA

ISS

2 references

1 reference

14 February 2019

The evolutionarily conserved EBR module of RALT/MIG6 mediates suppression of the EGFR catalytic activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

regulation of type B pancreatic cell proliferation

IDA

1 reference

14 February 2019

Glucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of ERK1 and ERK2 cascade

IMP

1 reference

14 February 2019

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

cellular response to epidermal growth factor stimulus

IDA

1 reference

14 February 2019

Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

cellular hyperosmotic response

1 reference

14 February 2019

Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditions, such as diabetic nephropathy. Possible role in the response to persistent stre

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

cellular response to dexamethasone stimulus

1 reference

14 February 2019

Glucocorticoid-induced suppression of β-cell proliferation is mediated by Mig6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

negative regulation of cardiac muscle hypertrophy in response to stress

1 reference

14 February 2019

Targeted expression of receptor-associated late transducer inhibits maladaptive hypertrophy via blocking epidermal growth factor receptor signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05432

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P05432

Cdc42 binding domain-like

1 reference

stated in

InterPro Release 71.0