Myelin-associated glycoprotein (Q28560018)

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mammalian protein found in Rattus norvegicus

siglec-4a
myelin-associated glycoprotein
S-MAG (C-term.)
sialic acid-binding Ig-like lectin 4a
Mag
brain neuron cytoplasmic protein 3

Language	Label	Description	Also known as
English	Myelin-associated glycoprotein	mammalian protein found in Rattus norvegicus	siglec-4a myelin-associated glycoprotein S-MAG (C-term.) sialic acid-binding Ig-like lectin 4a Mag brain neuron cytoplasmic protein 3

Statements

1 reference

25 May 2022

UniProt protein ID

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07722

Immunoglobulin-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P07722

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Immunoglobulin subtype, protein family

1 reference

based on heuristic

inferred from protein domain or family

CD80-like, immunoglobulin C2-set, protein family

1 reference

based on heuristic

inferred from protein domain or family

Immunoglobulin subtype 2, protein family

1 reference

based on heuristic

inferred from protein domain or family

immunoglobulin-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

signaling receptor binding

determination method

1 reference

14 February 2019

LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

protein binding

determination method

3 references

14 February 2019

The Nogo-66 receptor homolog NgR2 is a sialic acid-dependent receptor selective for myelin-associated glycoprotein

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Microtubule-associated protein 1B: a neuronal binding partner for myelin-associated glycoprotein

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

protein kinase binding

determination method

1 reference

14 February 2019

Opioid addiction and pregnancy: perinatal exposure to buprenorphine affects myelination in the developing brain

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

carbohydrate binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

sialic acid binding

determination method

4 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Molecular basis of the interactions of the Nogo-66 receptor and its homolog NgR2 with myelin-associated glycoprotein: development of NgROMNI-Fc, a novel antagonist of CNS myelin inhibition

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Sialic acid specificity of myelin-associated glycoprotein binding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

protein homodimerization activity

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

ganglioside GT1b binding

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Sialic acid specificity of myelin-associated glycoprotein binding

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

Myelin-associated glycoprotein demonstrated immunocytochemically in myelin and myelin-forming cells of developing rat

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

plasma membrane

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Expression of recombinant myelin-associated glycoprotein in primary Schwann cells promotes the initial investment of axons by myelinating Schwann cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

integral component of plasma membrane

determination method

3 references

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

integral component of membrane

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

paranode region of axon

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

determination method

1 reference

14 February 2019

Secreted glycoprotein myocilin is a component of the myelin sheath in peripheral nerves

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

biological process

nervous system development

determination method

1 reference

14 February 2019

Differential splicing of MAG transcripts during CNS and PNS development

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

negative regulation of neuron projection development

determination method

5 references

14 February 2019

Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Gangliosides and Nogo receptors independently mediate myelin-associated glycoprotein inhibition of neurite outgrowth in different nerve cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

LDL receptor-related protein-1 is a sialic-acid-independent receptor for myelin-associated glycoprotein that functions in neurite outgrowth inhibition by MAG and CNS myelin.

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

14 February 2019

Promotion of axon regeneration by myelin-associated glycoprotein and Nogo through divergent signals downstream of Gi/G

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

transmission of nerve impulse

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

central nervous system myelination

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

negative regulation of axon extension

determination method

1 reference

14 February 2019

Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

axon regeneration

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

positive regulation of myelination

determination method

1 reference

14 February 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

negative regulation of neuron differentiation

determination method

1 reference

14 February 2019

Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

positive regulation of astrocyte differentiation

determination method

1 reference

14 February 2019

Myelin-associated glycoprotein inhibits the neuronal differentiation of neural progenitors

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

cellular response to mechanical stimulus

determination method

1 reference

14 February 2019

Shear stress alters the expression of myelin-associated glycoprotein (MAG) and myelin basic protein (MBP) in Schwann cells

Rat genome database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

cell-cell adhesion via plasma-membrane adhesion molecules

determination method

1 reference

14 February 2019

Myelin-associated glycoprotein interacts with neurons via a sialic acid binding site at ARG118 and a distinct neurite inhibition site

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P07722

determination method

Identifiers

RefSeq protein ID

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSRNOP00000028544

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000028544

ENSRNOP00000041373

1 reference

ensembl Release 106

Ensembl protein ID

ENSRNOP00000041373

Sitelinks

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Wiktionary(0 entries)

Multilingual sites(0 entries)

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