Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding (Q28547736)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

author name string

Leidamarie Tirado-Lee

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

Megumi Yamashita

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

language of work or name

English

0 references

publication date

2015

0 references

published in

PLOS One

1 reference

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12 June 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

issue

6

1 reference

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12 June 2020

page(s)

e0128622

1 reference

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Creative Commons Attribution 4.0 International

12 June 2020

copyright license

start time

2 June 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4452722/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Crystal Structure of the Calcium Release-Activated Calcium Channel Orai

19 March 2017

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STIM1 gates the store-operated calcium channel ORAI1 in vitro

19 March 2017

1 reference

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STIM1 clusters and activates CRAC channels via direct binding of a cytosolic domain to Orai1

19 March 2017

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19 March 2017

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STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membrane

19 March 2017

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Expression of ORAII, a plasma membrane resident subunit of the CRAC channel, in rodent and non-rodent species

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Single-molecule analysis of diffusion and trapping of STIM1 and Orai1 at endoplasmic reticulum-plasma membrane junctions

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Orai channel pore properties and gating by STIM: implications from the Orai crystal structure

29 September 2017

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Emerging roles of store-operated Ca²⁺ entry through STIM and ORAI proteins in immunity, hemostasis and cancer

29 September 2017

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Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation

29 September 2017

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29 September 2017

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Stoichiometric requirements for trapping and gating of Ca2+ release-activated Ca2+ (CRAC) channels by stromal interaction molecule 1 (STIM1).

29 September 2017

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STIM1 and Orai1: novel targets for vascular diseases?

29 September 2017

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Competitive modulation of Ca2+ release-activated Ca2+ channel gating by STIM1 and 2-aminoethyldiphenyl borate

29 September 2017

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A single lysine in the N-terminal region of store-operated channels is critical for STIM1-mediated gating

29 September 2017

1 reference

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Activation of STIM1-Orai1 involves an intramolecular switching mechanism.

29 September 2017

1 reference

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Graded activation of CRAC channel by binding of different numbers of STIM1 to Orai1 subunits

29 September 2017

1 reference

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29 September 2017

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A basic sequence in STIM1 promotes Ca2+ influx by interacting with the C-terminal acidic coiled coil of Orai1.

29 September 2017

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Structural determinants of ion permeation in CRAC channels

29 September 2017

1 reference

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Molecular determinants of the coupling between STIM1 and Orai channels: differential activation of Orai1-3 channels by a STIM1 coiled-coil mutant

29 September 2017

1 reference

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A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels

29 September 2017

1 reference

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Increased hydrophobicity at the N terminus/membrane interface impairs gating of the severe combined immunodeficiency-related ORAI1 mutant

29 September 2017

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SOAR and the polybasic STIM1 domains gate and regulate Orai channels

29 September 2017

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Molecular clustering of STIM1 with Orai1/CRACM1 at the plasma membrane depends dynamically on depletion of Ca2+ stores and on electrostatic interactions.

29 September 2017

1 reference

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STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy

29 September 2017

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Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

29 September 2017

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Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation.

29 September 2017

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Orai1 mutations alter ion permeation and Ca2+-dependent fast inactivation of CRAC channels: evidence for coupling of permeation and gating

29 September 2017

1 reference

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The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER-plasma membrane junctions

29 September 2017

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Photobleaching-corrected FRET efficiency imaging of live cells

29 September 2017

1 reference

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Store-operated calcium entry modulates neuronal network activity in a model of chronic epilepsy.

29 September 2017

1 reference

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The C- and N-terminal STIM1 binding sites on Orai1 are required for both trapping and gating CRAC channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0128622

The extended transmembrane Orai1 N-terminal (ETON) region combines binding interface and gate for Orai1 activation by STIM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0128622

Aggregation of STIM1 underneath the plasma membrane induces clustering of Orai1

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0128622

Intramolecular shielding maintains the ER Ca²⁺ sensor STIM1 in an inactive conformation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26035642

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0128622

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

ADS bibcode

2015PLoSO..1028622T

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json

12 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26035642%20AND%20SRC:MED&resulttype=core&format=json