Comprehensive analyses of ventricular myocyte models identify targets exhibiting favorable rate dependence (Q28541597)

4

1 reference

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11 June 2020

5

Eric A Sobie

1 reference

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11 June 2020

author name string

Megan A Cummins

1

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11 June 2020

Pavan J Dalal

2

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11 June 2020

Marco Bugana

3

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PLOS Computational Biology

11 June 2020

language of work or name

English

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publication date

March 2014

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published in

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11 June 2020

volume

10

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11 June 2020

page(s)

e1003543

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11 June 2020

issue

3

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Creative Commons Attribution 4.0 International

11 June 2020

copyright license

start time

27 March 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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Role of action potential configuration and the contribution of C²⁺a and K⁺ currents to isoprenaline-induced changes in canine ventricular cells

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Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis

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Early afterdepolarizations and cardiac arrhythmias

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29 September 2017

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A tale of two dogs: analyzing two models of canine ventricular electrophysiology

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A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction

3 June 2018

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Phase 2 early afterdepolarization as a trigger of polymorphic ventricular tachycardia in acquired long-QT syndrome : direct evidence from intracellular recordings in the intact left ventricular wall

3 June 2018

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Reverse rate dependency is an intrinsic property of canine cardiac preparations.

21 January 2018

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Reverse rate-dependent changes are determined by baseline action potential duration in mammalian and human ventricular preparations.

21 January 2018

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Mechanism of reverse rate-dependent action of cardioactive agents.

21 January 2018

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A model for human ventricular tissue.

21 January 2018

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Yoga for the sinoatrial node: sarcoplasmic reticulum calcium release confers flexibility.

21 January 2018

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A meta-analysis of cardiac electrophysiology computational models.

21 January 2018

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Systematic characterization of the ionic basis of rabbit cellular electrophysiology using two ventricular models

21 January 2018

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Accumulation of slowly activating delayed rectifier potassium current (IKs) in canine ventricular myocytes.

21 January 2018

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Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle.

21 January 2018

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Proarrhythmic consequences of a KCNQ1 AKAP-binding domain mutation: computational models of whole cells and heterogeneous tissue.

21 January 2018

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Autonomic control of cardiac action potentials: role of potassium channel kinetics in response to sympathetic stimulation.

21 January 2018

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Mechanisms of ventricular rate adaptation as a predictor of arrhythmic risk

21 January 2018

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Regional differences in the delayed rectifier current (IKr and IKs) contribute to the differences in action potential duration in basal left ventricular myocytes in guinea-pig

21 January 2018

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Transmural heterogeneity of action potentials and Ito1 in myocytes isolated from the human right ventricle.

21 January 2018

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Ionic mechanism of electrical alternans

27 November 2018

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12 December 2020

Class III antiarrhythmic agents have a lot of potential but a long way to go. Reduced effectiveness and dangers of reverse use dependence

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12 December 2020

Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent. Specific block of rapidly activating delayed rectifier K+ current by dofetilide

1 reference

12 December 2020

Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle

1 reference

12 December 2020

Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells

1 reference

12 December 2020

Two components of delayed rectifier current in canine atrium and ventricle. Does IKs play a role in the reverse rate dependence of class III agents?

1 reference

12 December 2020

Amiodarone reduces transmural heterogeneity of repolarization in the human heart

1 reference

12 December 2020

Alternans and spiral breakup in a human ventricular tissue model

1 reference

12 December 2020

Relative contributions of TRIaD and QT to proarrhythmia

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12 December 2020

10.1371/JOURNAL.PCBI.1003543

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675446%20AND%20SRC:MED&resulttype=core&format=json

journals/ploscb/CumminsDBSS14

11 June 2020

DBLP publication ID

1 reference

DBLP Dataset 2021-01-02

release_vcb62i3j2vaz5kketxne7yf75y

28 January 2021

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/vcb62i3j2vaz5kketxne7yf75y

24 November 2022

mapped directly with Wikidata item

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2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675446%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675446%20AND%20SRC:MED&resulttype=core&format=json