Wnt4 is required for proper male as well as female sexual development (Q28513410)

Evidence that Sry is expressed in pre-Sertoli cells and Sertoli and granulosa cells have a common precursor.

GOA release 2020-03-11

author name string

Katherine Jeays-Ward

series ordinal

1

1 reference

25 January 2017

Mathieu Dandonneau

series ordinal

2

1 reference

25 January 2017

Amanda Swain

series ordinal

3

1 reference

25 January 2017

language of work or name

English

0 references

publication date

15 December 2004

1 reference

25 January 2017

Developmental Biology

1 reference

25 January 2017

276

1 reference

25 January 2017

431–440

1 reference

25 January 2017

2

1 reference

25 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Targeted mutagenesis of the endogenous mouse Mis gene promoter: in vivo definition of genetic pathways of vertebrate sexual development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Sertoli cell signaling by Desert hedgehog regulates the male germline

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Spatially dynamic expression ofSry in mouse genital ridges

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Circular transcripts of the testis-determining gene Sry in adult mouse testis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Müllerian hormone gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Mus poschiavinus Y chromosome in the C57BL/6J murine genome causes sex reversal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Endothelial and steroidogenic cell migration are regulated by WNT4 in the developing mammalian gonad.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Dax1 is required for testis determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Dax-1 (dosage-sensitive sex reversal-adrenal hypoplasia congenita critical region on the X chromosome, gene 1) gene transcription is regulated by wnt4 in the female developing gonad

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Disturbed expression of Sox9 in pre-sertoli cells underlies sex-reversal in mice b6.Ytir.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Dax1 antagonizes Sry action in mammalian sex determination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Female development in mammals is regulated by Wnt-4 signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Desert Hedgehog/Patched 1 signaling specifies fetal Leydig cell fate in testis organogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049

Role of Ahch in gonadal development and gametogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2004.08.049