Deficiency of the metalloproteinase-disintegrin ADAM8 is associated with thymic hyper-cellularity (Q28512812)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0072681

extracellular matrix-dependent thymocyte migration

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0072680

A disintegrin and metallopeptidase domain 8

1 reference

GOA release 2020-03-11

author name string

Klaus Gossens

1

1 reference

25 January 2017

Silvia Naus

2

1 reference

25 January 2017

Georg A. Holländer

3

1 reference

25 January 2017

Hermann J. Ziltener

Creative Commons Attribution 4.0 International

4

1 reference

25 January 2017

language of work or name

English

0 references

publication date

15 September 2010

1 reference

25 January 2017

1 reference

25 January 2017

5

1 reference

25 January 2017

e12766

1 reference

25 January 2017

9

1 reference

25 January 2017

start time

15 September 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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ADAM8 expression is associated with increased invasiveness and reduced patient survival in pancreatic cancer

19 March 2017

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Expression and regulation of the metalloproteinase ADAM-8 during human neutrophil pathophysiological activation and its catalytic activity on L-selectin shedding

19 March 2017

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Non-cell autonomous expression of TNF-alpha-converting enzyme ADAM17 is required for normal lymphocyte development

19 March 2017

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Alpha9beta1: a novel osteoclast integrin that regulates osteoclast formation and function

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ADAM8 as a novel serological and histochemical marker for lung cancer

19 March 2017

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Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes

19 March 2017

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Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death

19 March 2017

1 reference

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The metalloprotease disintegrin ADAM8. Processing by autocatalysis is required for proteolytic activity and cell adhesion

19 March 2017

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CD156 (human ADAM8): expression, primary amino acid sequence, and gene location

19 March 2017

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Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

19 March 2017

1 reference

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Spatial mapping of thymic stromal microenvironments reveals unique features influencing T lymphoid differentiation.

7 April 2017

1 reference

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Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25

29 September 2017

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Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration

29 September 2017

1 reference

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Clonal deletion of thymocytes can occur in the cortex with no involvement of the medulla

29 September 2017

1 reference

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Zoned out: functional mapping of stromal signaling microenvironments in the thymus

29 September 2017

1 reference

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Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness

29 September 2017

1 reference

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NCAM140 stimulates integrin-dependent cell migration by ectodomain shedding

29 September 2017

1 reference

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Metalloprotease-disintegrin ADAM8: expression analysis and targeted deletion in mice.

29 September 2017

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Regulation of matrix biology by matrix metalloproteinases

29 September 2017

1 reference

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Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

29 September 2017

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Mapping precursor movement through the postnatal thymus reveals specific microenvironments supporting defined stages of early lymphoid development

29 September 2017

1 reference

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The importation of hematogenous precursors by the thymus is a gated phenomenon in normal adult mice

29 September 2017

1 reference

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Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice

29 September 2017

1 reference

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Epitope analysis of antibodies recognising the cell proliferation associated nuclear antigen previously defined by the antibody Ki-67 (Ki-67 protein).

29 September 2017

1 reference

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Molecular cloning of cDNA encoding MS2 antigen, a novel cell surface antigen strongly expressed in murine monocytic lineage

29 September 2017

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Differential contribution of chemotaxis and substrate restriction to segregation of immature and mature thymocytes

29 September 2017

1 reference

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An ADAM family member with expression in thymic epithelial cells and related tissues

2 June 2018

1 reference

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Impairment of thymocyte development by dominant-negative Kuzbanian (ADAM-10) is rescued by the Notch ligand, delta-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012766

ADAM10 is essential for proteolytic activation of Notch during thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012766

Regulation of thymus size by competition for stromal niches among early T cell progenitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012766

Xenopus ADAM 13 is a metalloprotease required for cranial neural crest-cell migration.

21 January 2018

1 reference

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ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271).

21 January 2018

1 reference

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The cytokine RANKL produced by positively selected thymocytes fosters medullary thymic epithelial cells that express autoimmune regulator.

21 January 2018

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Heterogeneity among DN1 prothymocytes reveals multiple progenitors with different capacities to generate T cell and non-T cell lineages

21 January 2018

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12 December 2020

Thymus cell migration. Quantitative aspects of cellular traffic from the thymus to the periphery in mice

1 reference

12 December 2020

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell

1 reference

12 December 2020

Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1

1 reference

12 December 2020

Metalloproteinase-dependent control of thymocyte differentiation and proliferation

1 reference

12 December 2020

The detection of ADAM8 protein on cells of the human immune system and the demonstration of its expression on peripheral blood B cells, dendritic cells and monocyte subsets

1 reference

12 December 2020

Unbiased analysis, enrichment and purification of thymic stromal cells

1 reference

12 December 2020

Autoantigen-Specific Interactions with CD4+ Thymocytes Control Mature Medullary Thymic Epithelial Cell Cellularity

1 reference

12 December 2020