Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiency (Q28509844)

GOA release 2020-03-11

author

David Westaway

8

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author name string

Nathalie Daude

1

1 reference

24 January 2017

Serene Wohlgemuth

2

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24 January 2017

Rebecca Brown

3

1 reference

24 January 2017

Rose Pitstick

4

1 reference

24 January 2017

Hristina Gapeshina

5

1 reference

24 January 2017

Jing Yang

6

1 reference

24 January 2017

George A. Carlson

Proceedings of the National Academy of Sciences of the United States of America

7

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24 January 2017

language of work or name

English

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publication date

5 June 2012

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24 January 2017

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24 January 2017

109

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24 January 2017

23

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24 January 2017

9035–9040

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24 January 2017

Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Evolutionary descent of prion genes from the ZIP family of metal ion transporters

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Regulation of embryonic cell adhesion by the prion protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Mice devoid of PrP are resistant to scrapie

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Expression profiling reveals off-target gene regulation by RNAi

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Protease-resistant prions selectively decrease Shadoo protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Unexpected tolerance of alpha-cleavage of the prion protein to sequence variations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Agent-specific Shadoo responses in transmissible encephalopathies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Axonal prion protein is required for peripheral myelin maintenance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Olfactory behavior and physiology are disrupted in prion protein knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Association of a null allele of SPRN with variant Creutzfeldt-Jakob disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Cellular prion protein modulates defensive attention and innate fear-induced behaviour evoked in transgenic mice submitted to an agonistic encounter with the tropical coral snake Oxyrhopus guibei

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

New molecular insights into cellular survival and stress responses: neuroprotective role of cellular prion protein (PrPC).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

The role of PrP in health and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Post-natal knockout of prion protein alters hippocampal CA1 properties, but does not result in neurodegeneration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

The alpha-secretase-derived N-terminal product of cellular prion, N1, displays neuroprotective function in vitro and in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Cellular prion protein ablation impairs behavior as a function of age.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Changes in drinking and feeding habits of mice with experimental scrapie

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Scrapie-induced obesity in mice.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Distinct prion proteins in short and long scrapie incubation period mice

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Linkage of the scrapie-associated fibril protein (PrP) gene and Sinc using congenic mice and restriction fragment length polymorphism analysis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Pathologic conformations of prion proteins

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Imbalance of antioxidant defense in mice lacking cellular prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Enhanced susceptibility of Prnp-deficient mice to kainate-induced seizures, neuronal apoptosis, and death: Role of AMPA/kainate receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

The prion or the related Shadoo protein is required for early mouse embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Truncated forms of the human prion protein in normal brain and in prion diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

The C-terminal products of cellular prion protein processing, C1 and C2, exert distinct influence on p53-dependent staurosporine-induced caspase-3 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Neonatal lethality in transgenic mice expressing prion protein with a deletion of residues 105-125.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3384183

Altered circadian activity rhythms and sleep in mice devoid of prion protein

27 November 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202130109

Increased Sensitivity to Seizures in Mice Lacking Cellular Prion Protein

21 January 2018

1 reference

12 December 2020

Linkage of prion protein and scrapie incubation time genes

1 reference

12 December 2020

Sleep and sleep regulation in normal and prion protein-deficient mice

1 reference

12 December 2020

Overexpression of Shadoo protein in transgenic mice does not impact the pathogenesis of scrapie

1 reference

12 December 2020